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Entry version 135 (03 Jul 2019)
Sequence version 2 (15 Jan 2008)
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Protein

Transcriptional adapter 2-beta

Gene

TADA2B

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Coactivates PAX5-dependent transcription together with either SMARCA4 or GCN5L2.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri3 – 49ZZ-typePROSITE-ProRule annotationAdd BLAST47

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-3214847 HATs acetylate histones
R-HSA-5689880 Ub-specific processing proteases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Transcriptional adapter 2-beta
Alternative name(s):
ADA2-like protein beta
Short name:
ADA2-beta
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TADA2B
Synonyms:ADA2B
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:30781 TADA2B

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
608790 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q86TJ2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
93624

Open Targets

More...
OpenTargetsi
ENSG00000173011

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA165664556

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
TADA2B

Domain mapping of disease mutations (DMDM)

More...
DMDMi
166225686

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003137111 – 420Transcriptional adapter 2-betaAdd BLAST420

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q86TJ2

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q86TJ2

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q86TJ2

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q86TJ2

PeptideAtlas

More...
PeptideAtlasi
Q86TJ2

PRoteomics IDEntifications database

More...
PRIDEi
Q86TJ2

ProteomicsDB human proteome resource

More...
ProteomicsDBi
69705
69706 [Q86TJ2-2]
69707 [Q86TJ2-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q86TJ2

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q86TJ2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000173011 Expressed in 204 organ(s), highest expression level in amniotic fluid

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q86TJ2 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q86TJ2 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA035770

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with GCN5L2, SMARCA4, SMARCE1 and PAX5.

Component of the TFTC-HAT complex.

2 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

WithEntry#Exp.IntActNotes
AATFQ9NY614EBI-2512219,EBI-372428

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
125041, 26 interactors

ComplexPortal: manually curated resource of macromolecular complexes

More...
ComplexPortali
CPX-900 SAGA complex

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
Q86TJ2

Protein interaction database and analysis system

More...
IntActi
Q86TJ2, 7 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000308022

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q86TJ2

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini65 – 118SANTPROSITE-ProRule annotationAdd BLAST54

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri3 – 49ZZ-typePROSITE-ProRule annotationAdd BLAST47

Keywords - Domaini

Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0457 Eukaryota
COG5114 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000157318

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000007843

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q86TJ2

KEGG Orthology (KO)

More...
KOi
K15127

Identification of Orthologs from Complete Genome Data

More...
OMAi
FFENMHK

Database of Orthologous Groups

More...
OrthoDBi
812864at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q86TJ2

TreeFam database of animal gene trees

More...
TreeFami
TF313975

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00167 SANT, 1 hit
cd02335 ZZ_ADA2, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR041983 ADA2-like_ZZ
IPR016827 Ada2/TADA2
IPR009057 Homeobox-like_sf
IPR001005 SANT/Myb
IPR017884 SANT_dom
IPR000433 Znf_ZZ

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00249 Myb_DNA-binding, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF025024 Transcriptional_adaptor_2, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00717 SANT, 1 hit
SM00291 ZnF_ZZ, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF46689 SSF46689, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51293 SANT, 1 hit
PS01357 ZF_ZZ_1, 1 hit
PS50135 ZF_ZZ_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q86TJ2-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MAELGKKYCV YCLAEVSPLR FRCTECQDIE LCPECFSAGA EIGHHRRYHG
60 70 80 90 100
YQLVDGGRFT LWGPEAEGGW TSREEQLLLD AIEQFGFGNW EDMAAHVGAS
110 120 130 140 150
RTPQEVMEHY VSMYIHGNLG KACIPDTIPN RVTDHTCPSG GPLSPSLTTP
160 170 180 190 200
LPPLDISVAE QQQLGYMPLR DDYEIEYDQD AETLISGLSV NYDDDDVEIE
210 220 230 240 250
LKRAHVDMYV RKLKERQRRK NIARDYNLVP AFLGKDKKEK EKALKRKITK
260 270 280 290 300
EEKELRLKLR PLYQFMSCKE FDDLFENMHK EKMLRAKIRE LQRYRRNGIT
310 320 330 340 350
KMEESAEYEA ARHKREKRKE NKNLAGSKRG KEDGKDSEFA AIENLPGFEL
360 370 380 390 400
LSDREKVLCS SLNLSPARYV TVKTIIIKDH LQKRQGIPSK SRLPSYLDKV
410 420
LKKRILNFLT ESGWISRDAS
Length:420
Mass (Da):48,470
Last modified:January 15, 2008 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i89C3365128DF5EBC
GO
Isoform 2 (identifier: Q86TJ2-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     16-90: Missing.

Note: No experimental confirmation available.
Show »
Length:345
Mass (Da):39,914
Checksum:iB4171B04BBBB32C9
GO
Isoform 3 (identifier: Q86TJ2-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-92: Missing.

Show »
Length:328
Mass (Da):37,967
Checksum:iBD6453E0703FE736
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
D6RJ05D6RJ05_HUMAN
Transcriptional adapter 2-beta
TADA2B
129Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D6RC20D6RC20_HUMAN
Transcriptional adapter 2-beta
TADA2B
121Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH47794 differs from that shown. Contaminating sequence. Potential poly-A sequence.Curated
The sequence AAI01338 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti251E → K in CAE46064 (PubMed:17974005).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0301091 – 92Missing in isoform 3. 2 PublicationsAdd BLAST92
Alternative sequenceiVSP_03011016 – 90Missing in isoform 2. 1 PublicationAdd BLAST75

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK093974 mRNA Translation: BAG52792.1
AK096655 mRNA Translation: BAG53348.1
AC097382 Genomic DNA No translation available.
CH471131 Genomic DNA Translation: EAW82372.1
BC047794 mRNA Translation: AAH47794.1 Sequence problems.
BC101334 mRNA Translation: AAI01335.1
BC101335 mRNA Translation: AAI01336.1
BC101336 mRNA Translation: AAI01337.1
BC101337 mRNA Translation: AAI01338.1 Different initiation.
BX641147 mRNA Translation: CAE46064.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS47007.1 [Q86TJ2-1]

NCBI Reference Sequences

More...
RefSeqi
NP_689506.2, NM_152293.2 [Q86TJ2-1]
XP_011511897.1, XM_011513595.1 [Q86TJ2-3]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000310074; ENSP00000308022; ENSG00000173011 [Q86TJ2-1]
ENST00000512388; ENSP00000423947; ENSG00000173011 [Q86TJ2-2]
ENST00000515646; ENSP00000423181; ENSG00000173011 [Q86TJ2-3]

Database of genes from NCBI RefSeq genomes

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GeneIDi
93624

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:93624

UCSC genome browser

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UCSCi
uc003gjw.5 human [Q86TJ2-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK093974 mRNA Translation: BAG52792.1
AK096655 mRNA Translation: BAG53348.1
AC097382 Genomic DNA No translation available.
CH471131 Genomic DNA Translation: EAW82372.1
BC047794 mRNA Translation: AAH47794.1 Sequence problems.
BC101334 mRNA Translation: AAI01335.1
BC101335 mRNA Translation: AAI01336.1
BC101336 mRNA Translation: AAI01337.1
BC101337 mRNA Translation: AAI01338.1 Different initiation.
BX641147 mRNA Translation: CAE46064.1
CCDSiCCDS47007.1 [Q86TJ2-1]
RefSeqiNP_689506.2, NM_152293.2 [Q86TJ2-1]
XP_011511897.1, XM_011513595.1 [Q86TJ2-3]

3D structure databases

SMRiQ86TJ2
ModBaseiSearch...

Protein-protein interaction databases

BioGridi125041, 26 interactors
ComplexPortaliCPX-900 SAGA complex
CORUMiQ86TJ2
IntActiQ86TJ2, 7 interactors
STRINGi9606.ENSP00000308022

PTM databases

iPTMnetiQ86TJ2
PhosphoSitePlusiQ86TJ2

Polymorphism and mutation databases

BioMutaiTADA2B
DMDMi166225686

Proteomic databases

EPDiQ86TJ2
jPOSTiQ86TJ2
MaxQBiQ86TJ2
PaxDbiQ86TJ2
PeptideAtlasiQ86TJ2
PRIDEiQ86TJ2
ProteomicsDBi69705
69706 [Q86TJ2-2]
69707 [Q86TJ2-3]

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000310074; ENSP00000308022; ENSG00000173011 [Q86TJ2-1]
ENST00000512388; ENSP00000423947; ENSG00000173011 [Q86TJ2-2]
ENST00000515646; ENSP00000423181; ENSG00000173011 [Q86TJ2-3]
GeneIDi93624
KEGGihsa:93624
UCSCiuc003gjw.5 human [Q86TJ2-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
93624
DisGeNETi93624

GeneCards: human genes, protein and diseases

More...
GeneCardsi
TADA2B
HGNCiHGNC:30781 TADA2B
HPAiHPA035770
MIMi608790 gene
neXtProtiNX_Q86TJ2
OpenTargetsiENSG00000173011
PharmGKBiPA165664556

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG0457 Eukaryota
COG5114 LUCA
GeneTreeiENSGT00940000157318
HOGENOMiHOG000007843
InParanoidiQ86TJ2
KOiK15127
OMAiFFENMHK
OrthoDBi812864at2759
PhylomeDBiQ86TJ2
TreeFamiTF313975

Enzyme and pathway databases

ReactomeiR-HSA-3214847 HATs acetylate histones
R-HSA-5689880 Ub-specific processing proteases

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
TADA2B human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
93624

Protein Ontology

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PROi
PR:Q86TJ2

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
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Gene expression databases

BgeeiENSG00000173011 Expressed in 204 organ(s), highest expression level in amniotic fluid
ExpressionAtlasiQ86TJ2 baseline and differential
GenevisibleiQ86TJ2 HS

Family and domain databases

CDDicd00167 SANT, 1 hit
cd02335 ZZ_ADA2, 1 hit
InterProiView protein in InterPro
IPR041983 ADA2-like_ZZ
IPR016827 Ada2/TADA2
IPR009057 Homeobox-like_sf
IPR001005 SANT/Myb
IPR017884 SANT_dom
IPR000433 Znf_ZZ
PfamiView protein in Pfam
PF00249 Myb_DNA-binding, 1 hit
PIRSFiPIRSF025024 Transcriptional_adaptor_2, 1 hit
SMARTiView protein in SMART
SM00717 SANT, 1 hit
SM00291 ZnF_ZZ, 1 hit
SUPFAMiSSF46689 SSF46689, 2 hits
PROSITEiView protein in PROSITE
PS51293 SANT, 1 hit
PS01357 ZF_ZZ_1, 1 hit
PS50135 ZF_ZZ_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTAD2B_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q86TJ2
Secondary accession number(s): A0AUJ8
, A4QMR7, B3KSN0, B3KU86, Q6MZG9
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: January 15, 2008
Last modified: July 3, 2019
This is version 135 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 4
    Human chromosome 4: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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