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Entry version 108 (08 May 2019)
Sequence version 2 (02 Nov 2010)
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Protein

NUT family member 1

Gene

NUTM1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Plays a role in the regulation of proliferation. Regulates TERT expression by modulating SP1 binding to TERT promoter binding sites.1 Publication

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
NUT family member 1Curated
Alternative name(s):
Nuclear protein in testis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:NUTM1Imported
Synonyms:C15orf55, NUT
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 15

Organism-specific databases

Human Gene Nomenclature Database

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HGNCi
HGNC:29919 NUTM1

Online Mendelian Inheritance in Man (OMIM)

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MIMi
608963 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q86Y26

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cytoplasm, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the ‘Pathology and Biotech’ section provides information on the disease(s) associated with genetic variations in a given protein. The information is extracted from the scientific literature and diseases that are also described in the <a href="http://www.ncbi.nlm.nih.gov/sites/entrez?db=omim">OMIM</a> database are represented with a <a href="http://www.uniprot.org/diseases">controlled vocabulary</a> in the following way:<p><a href='/help/involvement_in_disease' target='_top'>More...</a></p>Involvement in diseasei

A chromosomal aberration involving NUTM1 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with BRD4 which produces a BRD4-NUTM1 fusion protein.1 Publication
A chromosomal aberration involving NUTM1 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;9)(q14;q34) with BRD3 which produces a BRD3-NUTM1 fusion protein.1 Publication

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi1046Q → R: Abolishes methylation by N6AMT1. 1 Publication1

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection describes interesting single amino acid sites on the sequence that are not defined in any other subsection. This subsection can be displayed in different sections (‘Function’, ‘PTM / Processing’, ‘Pathology and Biotech’) according to its content.<p><a href='/help/site' target='_top'>More...</a></p>Sitei5 – 6Breakpoint for translocation to form BRD4-NUTM1 and BRD3-NUTM1 fusion proteins2

Organism-specific databases

DisGeNET

More...
DisGeNETi
256646

MalaCards human disease database

More...
MalaCardsi
NUTM1

Open Targets

More...
OpenTargetsi
ENSG00000184507

Orphanet; a database dedicated to information on rare diseases and orphan drugs

More...
Orphaneti
443167 NUT midline carcinoma

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162378206

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
NUTM1

Domain mapping of disease mutations (DMDM)

More...
DMDMi
311033405

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003113941 – 1132NUT family member 1Add BLAST1132

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1026Phosphoserine1 Publication1
Modified residuei1029Phosphoserine1 Publication1
Modified residuei1031Phosphoserine1 Publication1
Modified residuei1046N5-methylglutamine1 Publication1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Methylated at Gln-1046 by N6AMT1.1 Publication
Phosphorylation on Ser-1026, Ser-1029 or Ser-1031 is important for cytoplasmic export.1 Publication

Keywords - PTMi

Methylation, Phosphoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

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jPOSTi
Q86Y26

PaxDb, a database of protein abundance averages across all three domains of life

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PaxDbi
Q86Y26

PeptideAtlas

More...
PeptideAtlasi
Q86Y26

PRoteomics IDEntifications database

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PRIDEi
Q86Y26

ProteomicsDB human proteome resource

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ProteomicsDBi
70355
70356 [Q86Y26-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

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iPTMneti
Q86Y26

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

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PhosphoSitePlusi
Q86Y26

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Specifically expressed in testis.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

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Bgeei
ENSG00000184507 Expressed in 83 organ(s), highest expression level in right testis

Genevisible search portal to normalized and curated expression data from Genevestigator

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Genevisiblei
Q86Y26 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA040421

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

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BioGridi
129174, 24 interactors

Protein interaction database and analysis system

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IntActi
Q86Y26, 24 interactors

Molecular INTeraction database

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MINTi
Q86Y26

STRING: functional protein association networks

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STRINGi
9606.ENSP00000444896

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi10 – 182Pro-richAdd BLAST173

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the NUT family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
ENOG410IJ5E Eukaryota
ENOG4111830 LUCA

Ensembl GeneTree

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GeneTreei
ENSGT00410000025793

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

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HOGENOMi
HOG000112470

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
Q86Y26

Identification of Orthologs from Complete Genome Data

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OMAi
TQTALNW

Database of Orthologous Groups

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OrthoDBi
425279at2759

Database for complete collections of gene phylogenies

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PhylomeDBi
Q86Y26

TreeFam database of animal gene trees

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TreeFami
TF337728

Family and domain databases

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR024310 NUT
IPR024309 NUT_N

The PANTHER Classification System

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PANTHERi
PTHR22879 PTHR22879, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12881 NUT, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 4 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q86Y26-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MASDGASALP GPDMSMKPSA APSPSPALPF LPPTSDPPDH PPREPPPQPI
60 70 80 90 100
MPSVFSPDNP LMLSAFPSSL LVTGDGGPCL SGAGAGKVIV KVKTEGGSAE
110 120 130 140 150
PSQTQNFILT QTALNSTAPG TPCGGLEGPA PPFVTASNVK TILPSKAVGV
160 170 180 190 200
SQEGPPGLPP QPPPPVAQLV PIVPLEKAWP GPHGTTGEGG PVATLSKPSL
210 220 230 240 250
GDRSKISKDV YENFRQWQRY KALARRHLSQ SPDTEALSCF LIPVLRSLAR
260 270 280 290 300
LKPTMTLEEG LPLAVQEWEH TSNFDRMIFY EMAERFMEFE AEEMQIQNTQ
310 320 330 340 350
LMNGSQGLSP ATPLKLDPLG PLASEVCQQP VYIPKKAASK TRAPRRRQRK
360 370 380 390 400
AQRPPAPEAP KEIPPEAVKE YVDIMEWLVG THLATGESDG KQEEEGQQQE
410 420 430 440 450
EEGMYPDPGL LSYINELCSQ KVFVSKVEAV IHPQFLADLL SPEKQRDPLA
460 470 480 490 500
LIEELEQEEG LTLAQLVQKR LMALEEEEDA EAPPSFSGAQ LDSSPSGSVE
510 520 530 540 550
DEDGDGRLRP SPGLQGAGGA ACLGKVSSSG KRAREVHGGQ EQALDSPRGM
560 570 580 590 600
HRDGNTLPSP SSWDLQPELA APQGTPGPLG VERRGSGKVI NQVSLHQDGH
610 620 630 640 650
LGGAGPPGHC LVADRTSEAL PLCWQGGFQP ESTPSLDAGL AELAPLQGQG
660 670 680 690 700
LEKQVLGLQK GQQTGGRGVL PQGKEPLAVP WEGSSGAMWG DDRGTPMAQS
710 720 730 740 750
YDQNPSPRAA GERDDVCLSP GVWLSSEMDA VGLELPVQIE EVIESFQVEK
760 770 780 790 800
CVTEYQEGCQ GLGSRGNISL GPGETLVPGD TESSVIPCGG TVAAAALEKR
810 820 830 840 850
NYCSLPGPLR ANSPPLRSKE NQEQSCETVG HPSDLWAEGC FPLLESGDST
860 870 880 890 900
LGSSKETLPP TCQGNLLIMG TEDASSLPEA SQEAGSRGNS FSPLLETIEP
910 920 930 940 950
VNILDVKDDC GLQLRVSEDT CPLNVHSYDP QGEGRVDPDL SKPKNLAPLQ
960 970 980 990 1000
ESQESYTTGT PKATSSHQGL GSTLPRRGTR NAIVPRETSV SKTHRSADRA
1010 1020 1030 1040 1050
KGKEKKKKEA EEEDEELSNF AYLLASKLSL SPREHPLSPH HASGGQGSQR
1060 1070 1080 1090 1100
ASHLLPAGAK GPSKLPYPVA KSGKRALAGG PAPTEKTPHS GAQLGVPREK
1110 1120 1130
PLALGVVRPS QPRKRRCDSF VTGRRKKRRR SQ
Length:1,132
Mass (Da):120,314
Last modified:November 2, 2010 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i5CB58C1B030399F4
GO
Isoform 2 (identifier: Q86Y26-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     235-365: Missing.
     565-573: LQPELAAPQ → PPTNGESQC
     574-1132: Missing.

Show »
Length:442
Mass (Da):46,352
Checksum:i95BABF1664CEE540
GO
Isoform 3 (identifier: Q86Y26-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-4: MASD → MFQRSNQDLKLGPYRKFSALSY

Note: No experimental confirmation available.
Show »
Length:1,150
Mass (Da):122,542
Checksum:i2E4F0F3BB53FC785
GO
Isoform 4 (identifier: Q86Y26-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-1: M → MVVTLGPGPDCLILEASRQPQLVPKPERM

Note: No experimental confirmation available.
Show »
Length:1,160
Mass (Da):123,341
Checksum:iD315516EBE03B8E5
GO

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAO22237 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti332Y → H in BAG63912 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_03723922P → L4 PublicationsCorresponds to variant dbSNP:rs374230Ensembl.1
Natural variantiVAR_037240781T → M. Corresponds to variant dbSNP:rs16959028Ensembl.1
Natural variantiVAR_037241785V → E. Corresponds to variant dbSNP:rs17236868Ensembl.1
Natural variantiVAR_037242973T → N. Corresponds to variant dbSNP:rs2279683Ensembl.1
Natural variantiVAR_037243985P → R. Corresponds to variant dbSNP:rs2279684Ensembl.1
Natural variantiVAR_0372441113R → H. Corresponds to variant dbSNP:rs2279685Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0556441 – 4MASD → MFQRSNQDLKLGPYRKFSAL SY in isoform 3. 1 Publication4
Alternative sequenceiVSP_0556451M → MVVTLGPGPDCLILEASRQP QLVPKPERM in isoform 4. 1 Publication1
Alternative sequenceiVSP_029559235 – 365Missing in isoform 2. 1 PublicationAdd BLAST131
Alternative sequenceiVSP_029560565 – 573LQPELAAPQ → PPTNGESQC in isoform 2. 1 Publication9
Alternative sequenceiVSP_029561574 – 1132Missing in isoform 2. 1 PublicationAdd BLAST559

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF482429 mRNA Translation: AAO39268.1
AY166680 mRNA Translation: AAO22237.1 Different initiation.
AK098568 mRNA Translation: BAC05337.1
AK302656 mRNA Translation: BAH13770.1
AK302680 mRNA Translation: BAG63912.1
AC021822 Genomic DNA No translation available.
AC025678 Genomic DNA No translation available.
CH471125 Genomic DNA Translation: EAW92304.1
BC114518 mRNA Translation: AAI14519.1
BC114567 mRNA Translation: AAI14568.1
AL137416 mRNA Translation: CAB70729.1

The Consensus CDS (CCDS) project

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CCDSi
CCDS32190.1 [Q86Y26-1]
CCDS61584.1 [Q86Y26-3]
CCDS61585.1 [Q86Y26-4]

Protein sequence database of the Protein Information Resource

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PIRi
T46461

NCBI Reference Sequences

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RefSeqi
NP_001271221.1, NM_001284292.1
NP_001271222.1, NM_001284293.1
NP_786883.1, NM_175741.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000333756; ENSP00000329448; ENSG00000184507 [Q86Y26-1]
ENST00000438749; ENSP00000407031; ENSG00000184507 [Q86Y26-3]
ENST00000537011; ENSP00000444896; ENSG00000184507 [Q86Y26-4]
ENST00000614490; ENSP00000478903; ENSG00000184507 [Q86Y26-1]

Database of genes from NCBI RefSeq genomes

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GeneIDi
256646

KEGG: Kyoto Encyclopedia of Genes and Genomes

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KEGGi
hsa:256646

UCSC genome browser

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UCSCi
uc001zif.4 human [Q86Y26-1]

Keywords - Coding sequence diversityi

Alternative splicing, Chromosomal rearrangement, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

<p>This subsection of the <a href="http://www.uniprot.org/manual/cross_references_section">Cross-references</a> section provides links to various web resources that are relevant for a specific protein.<p><a href='/help/web_resource' target='_top'>More...</a></p>Web resourcesi

Atlas of Genetics and Cytogenetics in Oncology and Haematology

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF482429 mRNA Translation: AAO39268.1
AY166680 mRNA Translation: AAO22237.1 Different initiation.
AK098568 mRNA Translation: BAC05337.1
AK302656 mRNA Translation: BAH13770.1
AK302680 mRNA Translation: BAG63912.1
AC021822 Genomic DNA No translation available.
AC025678 Genomic DNA No translation available.
CH471125 Genomic DNA Translation: EAW92304.1
BC114518 mRNA Translation: AAI14519.1
BC114567 mRNA Translation: AAI14568.1
AL137416 mRNA Translation: CAB70729.1
CCDSiCCDS32190.1 [Q86Y26-1]
CCDS61584.1 [Q86Y26-3]
CCDS61585.1 [Q86Y26-4]
PIRiT46461
RefSeqiNP_001271221.1, NM_001284292.1
NP_001271222.1, NM_001284293.1
NP_786883.1, NM_175741.2

3D structure databases

Database of comparative protein structure models

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ModBasei
Search...

SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGridi129174, 24 interactors
IntActiQ86Y26, 24 interactors
MINTiQ86Y26
STRINGi9606.ENSP00000444896

PTM databases

iPTMnetiQ86Y26
PhosphoSitePlusiQ86Y26

Polymorphism and mutation databases

BioMutaiNUTM1
DMDMi311033405

Proteomic databases

jPOSTiQ86Y26
PaxDbiQ86Y26
PeptideAtlasiQ86Y26
PRIDEiQ86Y26
ProteomicsDBi70355
70356 [Q86Y26-2]

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000333756; ENSP00000329448; ENSG00000184507 [Q86Y26-1]
ENST00000438749; ENSP00000407031; ENSG00000184507 [Q86Y26-3]
ENST00000537011; ENSP00000444896; ENSG00000184507 [Q86Y26-4]
ENST00000614490; ENSP00000478903; ENSG00000184507 [Q86Y26-1]
GeneIDi256646
KEGGihsa:256646
UCSCiuc001zif.4 human [Q86Y26-1]

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
256646
DisGeNETi256646

GeneCards: human genes, protein and diseases

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GeneCardsi
NUTM1
HGNCiHGNC:29919 NUTM1
HPAiHPA040421
MalaCardsiNUTM1
MIMi608963 gene
neXtProtiNX_Q86Y26
OpenTargetsiENSG00000184507
Orphaneti443167 NUT midline carcinoma
PharmGKBiPA162378206

GenAtlas: human gene database

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GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IJ5E Eukaryota
ENOG4111830 LUCA
GeneTreeiENSGT00410000025793
HOGENOMiHOG000112470
InParanoidiQ86Y26
OMAiTQTALNW
OrthoDBi425279at2759
PhylomeDBiQ86Y26
TreeFamiTF337728

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
NUTM1 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
256646

Protein Ontology

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PROi
PR:Q86Y26

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
Search...

Gene expression databases

BgeeiENSG00000184507 Expressed in 83 organ(s), highest expression level in right testis
GenevisibleiQ86Y26 HS

Family and domain databases

InterProiView protein in InterPro
IPR024310 NUT
IPR024309 NUT_N
PANTHERiPTHR22879 PTHR22879, 1 hit
PfamiView protein in Pfam
PF12881 NUT, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiNUTM1_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q86Y26
Secondary accession number(s): B4DZ00
, B7Z7Y4, E7EVE8, F5H4I6, Q86YS8, Q8N7F2, Q9NTB3
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 13, 2007
Last sequence update: November 2, 2010
Last modified: May 8, 2019
This is version 108 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  4. Human chromosome 15
    Human chromosome 15: entries, gene names and cross-references to MIM
  5. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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