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Entry version 131 (18 Sep 2019)
Sequence version 1 (01 Mar 2003)
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Protein

WAP four-disulfide core domain protein 3

Gene

WFDC3

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionProtease inhibitor, Serine protease inhibitor

Protein family/group databases

MEROPS protease database

More...
MEROPSi
I17.001

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
WAP four-disulfide core domain protein 3
Alternative name(s):
Putative protease inhibitor WAP14
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:WFDC3
Synonyms:WAP14
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 20

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:15957 WFDC3

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q8IUB2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
140686

Open Targets

More...
OpenTargetsi
ENSG00000124116

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA38067

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
WFDC3

Domain mapping of disease mutations (DMDM)

More...
DMDMi
32363334

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 24Sequence analysisAdd BLAST24
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000004138125 – 231WAP four-disulfide core domain protein 3Add BLAST207

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi33 ↔ 57PROSITE-ProRule annotation
Disulfide bondi40 ↔ 61PROSITE-ProRule annotation
Disulfide bondi44 ↔ 56PROSITE-ProRule annotation
Disulfide bondi50 ↔ 65PROSITE-ProRule annotation
Disulfide bondi76 ↔ 102PROSITE-ProRule annotation
Disulfide bondi85 ↔ 106PROSITE-ProRule annotation
Disulfide bondi89 ↔ 101PROSITE-ProRule annotation
Disulfide bondi95 ↔ 110PROSITE-ProRule annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi107N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi126 ↔ 150PROSITE-ProRule annotation
Disulfide bondi133 ↔ 154PROSITE-ProRule annotation
Disulfide bondi137 ↔ 149PROSITE-ProRule annotation
Disulfide bondi143 ↔ 158PROSITE-ProRule annotation
Disulfide bondi170 ↔ 195PROSITE-ProRule annotation
Disulfide bondi178 ↔ 199PROSITE-ProRule annotation
Disulfide bondi182 ↔ 194PROSITE-ProRule annotation
Disulfide bondi188 ↔ 203PROSITE-ProRule annotation
Glycosylationi217N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q8IUB2

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8IUB2

PeptideAtlas

More...
PeptideAtlasi
Q8IUB2

PRoteomics IDEntifications database

More...
PRIDEi
Q8IUB2

ProteomicsDB human proteome resource

More...
ProteomicsDBi
70534

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Ubiquitously expressed.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000124116 Expressed in 106 organ(s), highest expression level in right testis

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8IUB2 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8IUB2 HS

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
Q8IUB2, 3 interactors

Molecular INTeraction database

More...
MINTi
Q8IUB2

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000243938

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8IUB2

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini26 – 68WAP 1PROSITE-ProRule annotationAdd BLAST43
Domaini69 – 114WAP 2PROSITE-ProRule annotationAdd BLAST46
Domaini119 – 162WAP 3PROSITE-ProRule annotationAdd BLAST44
Domaini163 – 207WAP 4PROSITE-ProRule annotationAdd BLAST45

Keywords - Domaini

Repeat, Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410J2JX Eukaryota
ENOG41123U9 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00730000111454

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8IUB2

Identification of Orthologs from Complete Genome Data

More...
OMAi
RCITDET

Database of Orthologous Groups

More...
OrthoDBi
1631923at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8IUB2

TreeFam database of animal gene trees

More...
TreeFami
TF338375

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
4.10.75.10, 4 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR036645 Elafin-like_sf
IPR008197 WAP_dom
IPR029726 Wfdc3

The PANTHER Classification System

More...
PANTHERi
PTHR19441:SF46 PTHR19441:SF46, 2 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00095 WAP, 4 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00003 4DISULPHCORE

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00217 WAP, 4 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF57256 SSF57256, 4 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51390 WAP, 4 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

Q8IUB2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MMLSCLFLLK ALLALGSLES WITAGEHAKE GECPPHKNPC KELCQGDELC
60 70 80 90 100
PAEQKCCTTG CGRICRDIPK GRKRDCPRVI RKQSCLKRCI TDETCPGVKK
110 120 130 140 150
CCTLGCNKSC VVPISKQKLA EFGGECPADP LPCEELCDGD ASCPQGHKCC
160 170 180 190 200
STGCGRTCLG DIEGGRGGDC PKVLVGLCIV GCVMDENCQA GEKCCKSGCG
210 220 230
RFCVPPVLPP KLTMNPNWTV RSDSELEIPV P
Length:231
Mass (Da):24,687
Last modified:March 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i886B905654751DB3
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F2Z2G4F2Z2G4_HUMAN
WAP four-disulfide core domain prot...
WFDC3
137Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F2Z2G5F2Z2G5_HUMAN
WAP four-disulfide core domain prot...
WFDC3
94Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0Y2V5H0Y2V5_HUMAN
WAP four-disulfide core domain prot...
WFDC3
225Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAI02014 differs from that shown. Reason: Erroneous initiation.Curated
The sequence AAI02015 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti8 – 10LLK → IKE in CAC39444 (Ref. 3) Curated3
Sequence conflicti26 – 28EHA → RPS in AAI02014 (PubMed:15489334).Curated3

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_05295136H → D. Corresponds to variant dbSNP:rs6032538Ensembl.1
Natural variantiVAR_059962198G → S. Corresponds to variant dbSNP:rs6073907Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF488306 mRNA Translation: AAN70993.1
AL050348 Genomic DNA No translation available.
AL591713 mRNA Translation: CAC39444.1
BC102013 mRNA Translation: AAI02014.1 Different initiation.
BC102014 mRNA Translation: AAI02015.1 Different initiation.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS33478.1

NCBI Reference Sequences

More...
RefSeqi
NP_542181.1, NM_080614.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000243938; ENSP00000243938; ENSG00000124116

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
140686

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:140686

UCSC genome browser

More...
UCSCi
uc002xpf.1 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF488306 mRNA Translation: AAN70993.1
AL050348 Genomic DNA No translation available.
AL591713 mRNA Translation: CAC39444.1
BC102013 mRNA Translation: AAI02014.1 Different initiation.
BC102014 mRNA Translation: AAI02015.1 Different initiation.
CCDSiCCDS33478.1
RefSeqiNP_542181.1, NM_080614.1

3D structure databases

SMRiQ8IUB2
ModBaseiSearch...

Protein-protein interaction databases

IntActiQ8IUB2, 3 interactors
MINTiQ8IUB2
STRINGi9606.ENSP00000243938

Protein family/group databases

MEROPSiI17.001

Polymorphism and mutation databases

BioMutaiWFDC3
DMDMi32363334

Proteomic databases

jPOSTiQ8IUB2
PaxDbiQ8IUB2
PeptideAtlasiQ8IUB2
PRIDEiQ8IUB2
ProteomicsDBi70534

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
140686
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000243938; ENSP00000243938; ENSG00000124116
GeneIDi140686
KEGGihsa:140686
UCSCiuc002xpf.1 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
140686
DisGeNETi140686

GeneCards: human genes, protein and diseases

More...
GeneCardsi
WFDC3
HGNCiHGNC:15957 WFDC3
neXtProtiNX_Q8IUB2
OpenTargetsiENSG00000124116
PharmGKBiPA38067

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410J2JX Eukaryota
ENOG41123U9 LUCA
GeneTreeiENSGT00730000111454
InParanoidiQ8IUB2
OMAiRCITDET
OrthoDBi1631923at2759
PhylomeDBiQ8IUB2
TreeFamiTF338375

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
140686

Pharos

More...
Pharosi
Q8IUB2

Protein Ontology

More...
PROi
PR:Q8IUB2

Gene expression databases

BgeeiENSG00000124116 Expressed in 106 organ(s), highest expression level in right testis
ExpressionAtlasiQ8IUB2 baseline and differential
GenevisibleiQ8IUB2 HS

Family and domain databases

Gene3Di4.10.75.10, 4 hits
InterProiView protein in InterPro
IPR036645 Elafin-like_sf
IPR008197 WAP_dom
IPR029726 Wfdc3
PANTHERiPTHR19441:SF46 PTHR19441:SF46, 2 hits
PfamiView protein in Pfam
PF00095 WAP, 4 hits
PRINTSiPR00003 4DISULPHCORE
SMARTiView protein in SMART
SM00217 WAP, 4 hits
SUPFAMiSSF57256 SSF57256, 4 hits
PROSITEiView protein in PROSITE
PS51390 WAP, 4 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiWFDC3_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8IUB2
Secondary accession number(s): A6PVF2
, Q0P6A5, Q3T1C5, Q8TC52, Q9BQP3, Q9BQP4
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 27, 2003
Last sequence update: March 1, 2003
Last modified: September 18, 2019
This is version 131 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 20
    Human chromosome 20: entries, gene names and cross-references to MIM
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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