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Entry version 130 (16 Oct 2019)
Sequence version 2 (06 Feb 2007)
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Protein

IQ and ubiquitin-like domain-containing protein

Gene

IQUB

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May play roles in cilia formation and/or maintenance.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processCilium biogenesis/degradation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
IQ and ubiquitin-like domain-containing protein
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:IQUB
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:21995 IQUB

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q8NA54

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
154865

Open Targets

More...
OpenTargetsi
ENSG00000164675

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162392258

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q8NA54

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
IQUB

Domain mapping of disease mutations (DMDM)

More...
DMDMi
125950212

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002746011 – 791IQ and ubiquitin-like domain-containing proteinAdd BLAST791

Proteomic databases

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q8NA54

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8NA54

PeptideAtlas

More...
PeptideAtlasi
Q8NA54

PRoteomics IDEntifications database

More...
PRIDEi
Q8NA54

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
72638 [Q8NA54-1]
72639 [Q8NA54-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8NA54

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8NA54

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000164675 Expressed in 95 organ(s), highest expression level in sperm

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8NA54 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8NA54 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA049626

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with ZMYND10.

1 Publication

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
127562, 22 interactors

Protein interaction database and analysis system

More...
IntActi
Q8NA54, 50 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000417769

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1791
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8NA54

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
Q8NA54

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini131 – 207Ubiquitin-likePROSITE-ProRule annotationAdd BLAST77
Domaini338 – 367IQAdd BLAST30

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IEKT Eukaryota
ENOG4111FX1 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000014326

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8NA54

Identification of Orthologs from Complete Genome Data

More...
OMAi
NWRRWIL

Database of Orthologous Groups

More...
OrthoDBi
508546at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8NA54

TreeFam database of animal gene trees

More...
TreeFami
TF323180

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR037695 IQUB
IPR029071 Ubiquitin-like_domsf
IPR000626 Ubiquitin_dom

The PANTHER Classification System

More...
PANTHERi
PTHR21074 PTHR21074, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00240 ubiquitin, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF54236 SSF54236, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50053 UBIQUITIN_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8NA54-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSNQQEKYEA QNIVNSTEES DDAFDTVTIP VPSEEPQESD QTEEHESGIE
60 70 80 90 100
QFSESHAIHV EEQSDQSFSS LEPDNEQLME EVISPRQVSY TPQHHEKQYA
110 120 130 140 150
MQRPNDDSLA FLDKIKSVKE SLQESVEDSL ATVKVVLIPV GQEIVIPFKV
160 170 180 190 200
DTILKYLKDH FSHLLGIPHS VLQIRYSGKI LKNNETLVQH GVKPQEIVQV
210 220 230 240 250
EIFSTNPDLY PVRRIDGLTD VSQIITVTVQ TGLDQYQQVP VEIVKSDFHK
260 270 280 290 300
PFLGGFRHKV TGVEYHNAGT QTVPKRIPER LSIFCRDTQT VFQKKNLQQT
310 320 330 340 350
TNTTSTQMTN IGVYVSNMTD KLVTPGKYFS AAEYHAQRLK AVIVIQTYYR
360 370 380 390 400
QWHAKIFVEN LRRQKSLRLE WETQQELRKI REKEEWIKLD YHRRHNPKTN
410 420 430 440 450
EDFEFLYNAL EFWRQEELTR INQSFTGAER KAALCELLEK ETQIIASIGR
460 470 480 490 500
HRYIAYMANQ EAAIQAFLDK CSAPKIWRTP NGKTIEMDTQ FTIRARELQN
510 520 530 540 550
IYKCIMLKNI SQDERLDVLL TLKHTVKEHE CKLTQEILEL IDREVDLMMR
560 570 580 590 600
GVKHHNLEGL RKRIATLFFH YIKTPLFNPE VAKYLKVPQD PLKFYKKIYF
610 620 630 640 650
CHSCQLYLPS TEFSVSSTSR RIYRCRNCIN LQNEAQKRES FLKYKCLLQQ
660 670 680 690 700
LYYTEADYED DSKIAFLMQL QDIQYLTENI WASQSVLSAC DNLSDLVMVR
710 720 730 740 750
WNKSLEWSPW NCILLTKDEA AAHLKLTSIE EGYERSFIHK IKHKHILAKN
760 770 780 790
YFSQVPVLAS FILDDGEIDE IRWKYHSDTT PKIIESQRPP H
Length:791
Mass (Da):92,581
Last modified:February 6, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i3D16F8BF4BAED522
GO
Isoform 2 (identifier: Q8NA54-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     587-680: VPQDPLKFYK...QDIQYLTENI → MGGEYLSMAL
     681-791: Missing.

Note: No experimental confirmation available.
Show »
Length:596
Mass (Da):69,382
Checksum:i0F99A639616E100E
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A1A4Z1A1A4Z1_HUMAN
IQ and ubiquitin-like domain-contai...
IQUB
421Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti4Q → R in BAC04074 (PubMed:14702039).Curated1
Sequence conflicti252F → S in BAC04074 (PubMed:14702039).Curated1
Sequence conflicti343I → T in BAC04074 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_030332126V → M1 PublicationCorresponds to variant dbSNP:rs10255061Ensembl.1
Natural variantiVAR_030333691D → N. Corresponds to variant dbSNP:rs17146009Ensembl.1
Natural variantiVAR_036291735R → H in a colorectal cancer sample; somatic mutation. 1 PublicationCorresponds to variant dbSNP:rs1525626Ensembl.1
Natural variantiVAR_030334735R → P. Corresponds to variant dbSNP:rs1525626Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_022830587 – 680VPQDP…LTENI → MGGEYLSMAL in isoform 2. 1 PublicationAdd BLAST94
Alternative sequenceiVSP_022831681 – 791Missing in isoform 2. 1 PublicationAdd BLAST111

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK093153 mRNA Translation: BAC04074.1
AK093393 mRNA Translation: BAC04153.1
CH236947 Genomic DNA Translation: EAL24336.1
BC026173 mRNA Translation: AAH26173.1
BC036121 mRNA Translation: AAH36121.1
BC091520 mRNA Translation: AAH91520.1
BC128181 mRNA Translation: AAI28182.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS5787.1 [Q8NA54-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001269784.1, NM_001282855.1 [Q8NA54-1]
NP_001308222.1, NM_001321293.1 [Q8NA54-1]
NP_849149.3, NM_178827.4 [Q8NA54-1]
XP_005250218.1, XM_005250161.3 [Q8NA54-1]
XP_011514135.1, XM_011515833.2 [Q8NA54-1]
XP_011514136.1, XM_011515834.2 [Q8NA54-1]
XP_016867260.1, XM_017011771.1 [Q8NA54-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000324698; ENSP00000324882; ENSG00000164675 [Q8NA54-1]
ENST00000466202; ENSP00000417769; ENSG00000164675 [Q8NA54-1]
ENST00000484508; ENSP00000417285; ENSG00000164675 [Q8NA54-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
154865

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:154865

UCSC genome browser

More...
UCSCi
uc003vkn.4 human [Q8NA54-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK093153 mRNA Translation: BAC04074.1
AK093393 mRNA Translation: BAC04153.1
CH236947 Genomic DNA Translation: EAL24336.1
BC026173 mRNA Translation: AAH26173.1
BC036121 mRNA Translation: AAH36121.1
BC091520 mRNA Translation: AAH91520.1
BC128181 mRNA Translation: AAI28182.1
CCDSiCCDS5787.1 [Q8NA54-1]
RefSeqiNP_001269784.1, NM_001282855.1 [Q8NA54-1]
NP_001308222.1, NM_001321293.1 [Q8NA54-1]
NP_849149.3, NM_178827.4 [Q8NA54-1]
XP_005250218.1, XM_005250161.3 [Q8NA54-1]
XP_011514135.1, XM_011515833.2 [Q8NA54-1]
XP_011514136.1, XM_011515834.2 [Q8NA54-1]
XP_016867260.1, XM_017011771.1 [Q8NA54-1]

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2DAFNMR-A123-227[»]
SMRiQ8NA54
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGridi127562, 22 interactors
IntActiQ8NA54, 50 interactors
STRINGi9606.ENSP00000417769

PTM databases

iPTMnetiQ8NA54
PhosphoSitePlusiQ8NA54

Polymorphism and mutation databases

BioMutaiIQUB
DMDMi125950212

Proteomic databases

MassIVEiQ8NA54
PaxDbiQ8NA54
PeptideAtlasiQ8NA54
PRIDEiQ8NA54
ProteomicsDBi72638 [Q8NA54-1]
72639 [Q8NA54-2]

Genome annotation databases

EnsembliENST00000324698; ENSP00000324882; ENSG00000164675 [Q8NA54-1]
ENST00000466202; ENSP00000417769; ENSG00000164675 [Q8NA54-1]
ENST00000484508; ENSP00000417285; ENSG00000164675 [Q8NA54-2]
GeneIDi154865
KEGGihsa:154865
UCSCiuc003vkn.4 human [Q8NA54-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
154865
DisGeNETi154865

GeneCards: human genes, protein and diseases

More...
GeneCardsi
IQUB
HGNCiHGNC:21995 IQUB
HPAiHPA049626
neXtProtiNX_Q8NA54
OpenTargetsiENSG00000164675
PharmGKBiPA162392258

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IEKT Eukaryota
ENOG4111FX1 LUCA
GeneTreeiENSGT00390000014326
InParanoidiQ8NA54
OMAiNWRRWIL
OrthoDBi508546at2759
PhylomeDBiQ8NA54
TreeFamiTF323180

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
IQUB human
EvolutionaryTraceiQ8NA54

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
154865
PharosiQ8NA54

Protein Ontology

More...
PROi
PR:Q8NA54

Gene expression databases

BgeeiENSG00000164675 Expressed in 95 organ(s), highest expression level in sperm
ExpressionAtlasiQ8NA54 baseline and differential
GenevisibleiQ8NA54 HS

Family and domain databases

InterProiView protein in InterPro
IPR037695 IQUB
IPR029071 Ubiquitin-like_domsf
IPR000626 Ubiquitin_dom
PANTHERiPTHR21074 PTHR21074, 1 hit
PfamiView protein in Pfam
PF00240 ubiquitin, 1 hit
SUPFAMiSSF54236 SSF54236, 1 hit
PROSITEiView protein in PROSITE
PS50053 UBIQUITIN_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiIQUB_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8NA54
Secondary accession number(s): A4D0X0
, Q49AL6, Q4G189, Q5BJD9, Q6NUH6, Q8N9Y2
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 6, 2007
Last sequence update: February 6, 2007
Last modified: October 16, 2019
This is version 130 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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