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Entry version 74 (31 Jul 2019)
Sequence version 1 (01 Mar 2002)
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Protein
Submitted name:

PFTAIRE-interacting factor 1B

Gene

Pif1B

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
PFTAIRE-interacting factor 1BImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Pif1BImported
Synonyms:PIF-1Imported
ORF Names:CG33720Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora

Organism-specific databases

Drosophila genome database

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FlyBasei
FBgn0046874 Pif1B

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
Q8WTI7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0046874 Expressed in 7 organ(s), highest expression level in adult organism

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

WithEntry#Exp.IntActNotes
Q7KM035EBI-448819,EBI-448799

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
Q8WTI7, 1 interactor

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 95DisorderedSequence analysisAdd BLAST95
Regioni107 – 131DisorderedSequence analysisAdd BLAST25
Regioni183 – 219DisorderedSequence analysisAdd BLAST37
Regioni243 – 296DisorderedSequence analysisAdd BLAST54
Regioni585 – 609DisorderedSequence analysisAdd BLAST25
Regioni749 – 768DisorderedSequence analysisAdd BLAST20

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili669 – 689Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1 – 31PolyampholyteSequence analysisAdd BLAST31
Compositional biasi108 – 131PolarSequence analysisAdd BLAST24
Compositional biasi197 – 219PolarSequence analysisAdd BLAST23

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410J5HD Eukaryota
ENOG410XX92 LUCA

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q8WTI7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MYMQHERHSD SDPNSRHQQT EASHMRDHWK PSKSQQSQQS DRVDPHDKPS
60 70 80 90 100
QTAVSFLQKH HTPKNPESKA NPDDGASCSC TAKRSKSADP PAVKAHTCAC
110 120 130 140 150
NTDPSPCGLG HQEKSSSRKP CSQKTSVTEP EKASSFKSAI TACTKELLDP
160 170 180 190 200
CTCGAHPPYW AGQSNLVTGP SYSRAMDPFS STLAPLHRPG ASKGSFGRSK
210 220 230 240 250
SLASLPSKSN PPTQSGVTWL SALKDPESTC CSSKEDERPA CTCNATQTNQ
260 270 280 290 300
DPSMSSLPQS HPNYRSMTSK SSNFRAPNPR NQPSFGPGDE TSATTRSQSI
310 320 330 340 350
VGQVTCLCAS EHQPTKAFVS SLADRECPNE IQIAPCPSTR IHHPSGFAQF
360 370 380 390 400
TDCQNSQGDP STSFRSRKVS VKGQEEFCDC DASDNFSELS DPIQTSLHTH
410 420 430 440 450
RSLSGGSCLC NDDADPPKEP EKATCVSKQC QCSSNDELQG MQSAQAGTGY
460 470 480 490 500
QTPEDLCGNR AMACCSRKER ILMLMEKLTS PGCDCGISRP CLTQQLFREL
510 520 530 540 550
TLLLRSEKDD AVAPADEASP PCLTFDECCT AQHAGNGEGD PVEKPPSKRE
560 570 580 590 600
LQRVECFHQL EEYLCKCFLP PAEPQIPETD IYAFELDPDF PPEPEPKSPK
610 620 630 640 650
ENDNMQPCQC PEQFFDIGNA LTCSGDGLDD DFFRDCEDDE EVKKFESKDD
660 670 680 690 700
GKATTEPDLC QSLKAFIDKE LQEILAEEAN KEGEEVEEKT PSTVLREICE
710 720 730 740 750
RPTTVASPEE EEKPEQIECP FAGMVSCPPW TTQQTDWAAF PYNLDPCAQK
760 770 780 790 800
ESPSPAPRGP RTGLLPEGPL SPDMRNLCEQ LLRKALKDCG LCGGDDVYSC
810 820 830 840 850
EDDVCEECAL NCEECPEDCP LEQCEECDDE CPPEQQGCLC CHCRALICDE
860 870 880 890 900
ECKTVANTLR SGMCDPLCEM KYFIDSIIVD MHAMDCVLGN KKAKPKHLKA
910 920 930 940 950
TDSTNRGGPG DSFPVKIKSV WPLGNTALYV QWQLEDCRAV AGYEIYLDGH
960 970 980 990 1000
LTNRFYSFRH EAGVITNADV TNPHQVVVRA VAVGQEFPGE GPGKDATQEC
1010 1020 1030 1040
GCQAVALAHP ELKAGAQRPW SPSLYYYDPN QLPPAEDVQP C
Length:1,041
Mass (Da):114,032
Last modified:March 1, 2002 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i19E2D3141A5CF2A5
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
AF273707 mRNA Translation: AAL35410.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF273707 mRNA Translation: AAL35410.1

3D structure databases

Database of comparative protein structure models

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ModBasei
Search...

SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

IntActiQ8WTI7, 1 interactor

Proteomic databases

PRIDEiQ8WTI7

Organism-specific databases

FlyBaseiFBgn0046874 Pif1B

Phylogenomic databases

eggNOGiENOG410J5HD Eukaryota
ENOG410XX92 LUCA

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Pif1B fly

Gene expression databases

BgeeiFBgn0046874 Expressed in 7 organ(s), highest expression level in adult organism

Family and domain databases

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ8WTI7_DROME
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8WTI7
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2002
Last sequence update: March 1, 2002
Last modified: July 31, 2019
This is version 74 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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