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Entry version 132 (08 May 2019)
Sequence version 1 (01 Dec 2001)
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Protein

Ribonuclease P/MRP protein subunit POP5

Gene

POP5

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends (PubMed:11413139, PubMed:30454648). Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences (PubMed:28115465).3 Publications

Miscellaneous

The last C-terminal 19 amino acids are not required for complex association and RNase activity.

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolase, RNA-binding
Biological processrRNA processing, tRNA processing

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-6784531 tRNA processing in the nucleus

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Ribonuclease P/MRP protein subunit POP5 (EC:3.1.26.52 Publications)
Short name:
hPop5
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:POP5
ORF Names:AD-008, HSPC004, x0003
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 12

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:17689 POP5

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
609992 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q969H6

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
51367

Open Targets

More...
OpenTargetsi
ENSG00000167272

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA128394660

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
POP5

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74731042

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002390071 – 163Ribonuclease P/MRP protein subunit POP5Add BLAST163

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei154PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q969H6

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q969H6

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q969H6

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q969H6

PeptideAtlas

More...
PeptideAtlasi
Q969H6

PRoteomics IDEntifications database

More...
PRIDEi
Q969H6

ProteomicsDB human proteome resource

More...
ProteomicsDBi
75765
75766 [Q969H6-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q969H6

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q969H6

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000167272 Expressed in 223 organ(s), highest expression level in right adrenal gland

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q969H6 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA047598
HPA069204

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of nuclear RNase P and RNase MRP ribonucleoproteins (PubMed:11413139, PubMed:15096576, PubMed:16723659, PubMed:30454648). RNase P consists of a catalytic RNA moiety and 10 different protein chains; POP1, POP4, POP5, POP7, RPP14, RPP21, RPP25, RPP30, RPP38 and RPP40 (PubMed:11413139, PubMed:15096576, PubMed:16723659, PubMed:30454648). Within the RNase P complex, POP1, POP7 and RPP25 form the 'finger' subcomplex, POP5, RPP14, RPP40 and homodimeric RPP30 form the 'palm' subcomplex, and RPP21, POP4 and RPP38 form the 'wrist' subcomplex. All subunits of the RNase P complex interact with the catalytic RNA (PubMed:30454648). Several subunits of RNase P are also part of the RNase MRP complex. RNase MRP consists of a catalytic RNA moiety and about 8 protein subunits; POP1, POP7, RPP25, RPP30, RPP38, RPP40 and possibly also POP4 and POP5 (PubMed:11413139, PubMed:15096576, PubMed:16723659).

4 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
119502, 24 interactors

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
Q969H6

Protein interaction database and analysis system

More...
IntActi
Q969H6, 19 interactors

Molecular INTeraction database

More...
MINTi
Q969H6

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000350098

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q969H6

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4639 Eukaryota
COG1369 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000012331

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000293345

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q969H6

KEGG Orthology (KO)

More...
KOi
K03537

Identification of Orthologs from Complete Genome Data

More...
OMAi
NRYIAVQ

Database of Orthologous Groups

More...
OrthoDBi
1492689at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q969H6

TreeFam database of animal gene trees

More...
TreeFami
TF317496

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.70.3250, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR016819 RNase_P/MRP_POP5
IPR002759 RNase_P/MRP_subunit
IPR038085 Rnp2-like_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01900 RNase_P_Rpp14, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF023803 Ribonuclease_P_prd, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF160350 SSF160350, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q969H6-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MVRFKHRYLL CELVSDDPRC RLSLDDRVLS SLVRDTIARV HGTFGAAACS
60 70 80 90 100
IGFAVRYLNA YTGIVLLRCR KEFYQLVWSA LPFITYLENK GHRYPCFFNT
110 120 130 140 150
LHVGGTIRTC QKFLIQYNRR QLLILLQNCT DEGEREAIQK SVTRSCLLEE
160
EEESGEEAAE AME
Length:163
Mass (Da):18,820
Last modified:December 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iDF436E60B3DD50C1
GO
Isoform 2 (identifier: Q969H6-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     55-104: Missing.

Note: No experimental confirmation available.
Show »
Length:113
Mass (Da):12,826
Checksum:i1004F004EBE8E949
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti47 – 48AA → P in AAF17213 (PubMed:10931946).Curated2
Sequence conflicti47 – 48AA → P in AAD20966 (PubMed:11042152).Curated2
Sequence conflicti99N → D in BAD96926 (Ref. 5) Curated1
Sequence conflicti102H → R in BAD96926 (Ref. 5) Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_04273355 – 104Missing in isoform 2. 1 PublicationAdd BLAST50

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AJ306296 mRNA Translation: CAC59822.1
AF117232 mRNA Translation: AAF17213.1
AF070660 mRNA Translation: AAD20966.1
AK303144 mRNA Translation: BAG64248.1
AK223206 mRNA Translation: BAD96926.1
AC063943 Genomic DNA No translation available.
CH471054 Genomic DNA Translation: EAW98206.1
BC012505 mRNA Translation: AAH12505.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS9202.1 [Q969H6-1]
CCDS9203.1 [Q969H6-2]

NCBI Reference Sequences

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RefSeqi
NP_057002.2, NM_015918.3 [Q969H6-1]
NP_937845.1, NM_198202.1 [Q969H6-2]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000341039; ENSP00000341791; ENSG00000167272 [Q969H6-2]
ENST00000357500; ENSP00000350098; ENSG00000167272 [Q969H6-1]

Database of genes from NCBI RefSeq genomes

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GeneIDi
51367

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:51367

UCSC genome browser

More...
UCSCi
uc001tys.3 human [Q969H6-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ306296 mRNA Translation: CAC59822.1
AF117232 mRNA Translation: AAF17213.1
AF070660 mRNA Translation: AAD20966.1
AK303144 mRNA Translation: BAG64248.1
AK223206 mRNA Translation: BAD96926.1
AC063943 Genomic DNA No translation available.
CH471054 Genomic DNA Translation: EAW98206.1
BC012505 mRNA Translation: AAH12505.1
CCDSiCCDS9202.1 [Q969H6-1]
CCDS9203.1 [Q969H6-2]
RefSeqiNP_057002.2, NM_015918.3 [Q969H6-1]
NP_937845.1, NM_198202.1 [Q969H6-2]

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

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RCSB PDBi

Protein Data Bank Japan

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PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
6AHRelectron microscopy3.92E1-163[»]
6AHUelectron microscopy3.66E1-163[»]
SMRiQ969H6
ModBaseiSearch...

Protein-protein interaction databases

BioGridi119502, 24 interactors
CORUMiQ969H6
IntActiQ969H6, 19 interactors
MINTiQ969H6
STRINGi9606.ENSP00000350098

PTM databases

iPTMnetiQ969H6
PhosphoSitePlusiQ969H6

Polymorphism and mutation databases

BioMutaiPOP5
DMDMi74731042

Proteomic databases

EPDiQ969H6
jPOSTiQ969H6
MaxQBiQ969H6
PaxDbiQ969H6
PeptideAtlasiQ969H6
PRIDEiQ969H6
ProteomicsDBi75765
75766 [Q969H6-2]

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000341039; ENSP00000341791; ENSG00000167272 [Q969H6-2]
ENST00000357500; ENSP00000350098; ENSG00000167272 [Q969H6-1]
GeneIDi51367
KEGGihsa:51367
UCSCiuc001tys.3 human [Q969H6-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
51367
DisGeNETi51367

GeneCards: human genes, protein and diseases

More...
GeneCardsi
POP5
HGNCiHGNC:17689 POP5
HPAiHPA047598
HPA069204
MIMi609992 gene
neXtProtiNX_Q969H6
OpenTargetsiENSG00000167272
PharmGKBiPA128394660

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG4639 Eukaryota
COG1369 LUCA
GeneTreeiENSGT00390000012331
HOGENOMiHOG000293345
InParanoidiQ969H6
KOiK03537
OMAiNRYIAVQ
OrthoDBi1492689at2759
PhylomeDBiQ969H6
TreeFamiTF317496

Enzyme and pathway databases

ReactomeiR-HSA-6784531 tRNA processing in the nucleus

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
POP5 human

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
POP5

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
51367

Protein Ontology

More...
PROi
PR:Q969H6

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000167272 Expressed in 223 organ(s), highest expression level in right adrenal gland
GenevisibleiQ969H6 HS

Family and domain databases

Gene3Di3.30.70.3250, 1 hit
InterProiView protein in InterPro
IPR016819 RNase_P/MRP_POP5
IPR002759 RNase_P/MRP_subunit
IPR038085 Rnp2-like_sf
PfamiView protein in Pfam
PF01900 RNase_P_Rpp14, 1 hit
PIRSFiPIRSF023803 Ribonuclease_P_prd, 1 hit
SUPFAMiSSF160350 SSF160350, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPOP5_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q969H6
Secondary accession number(s): A6NL80, Q53FS5, Q9Y2Q6
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2006
Last sequence update: December 1, 2001
Last modified: May 8, 2019
This is version 132 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  4. Human chromosome 12
    Human chromosome 12: entries, gene names and cross-references to MIM
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