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Entry version 143 (18 Sep 2019)
Sequence version 1 (01 Dec 2001)
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Protein

Protein phosphatase 1 regulatory subunit 14A

Gene

PPP1R14A

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Inhibitor of PPP1CA. Has over 1000-fold higher inhibitory activity when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionProtein phosphatase inhibitor

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-5625740 RHO GTPases activate PKNs

SIGNOR Signaling Network Open Resource

More...
SIGNORi
Q96A00

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein phosphatase 1 regulatory subunit 14A
Alternative name(s):
17 kDa PKC-potentiated inhibitory protein of PP1
Protein kinase C-potentiated inhibitor protein of 17 kDa
Short name:
CPI-17
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PPP1R14A
Synonyms:CPI17, PPP1INL
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:14871 PPP1R14A

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
608153 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q96A00

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
94274

Open Targets

More...
OpenTargetsi
ENSG00000167641

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA33623

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q96A00

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
PPP1R14A

Domain mapping of disease mutations (DMDM)

More...
DMDMi
55583974

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000714861 – 147Protein phosphatase 1 regulatory subunit 14AAdd BLAST147

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei26PhosphoserineCombined sources1
Modified residuei38Phosphothreonine; by PKC1 Publication1
Modified residuei128PhosphoserineCombined sources1
Modified residuei134PhosphoserineCombined sources1
Modified residuei136PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q96A00

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q96A00

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q96A00

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q96A00

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q96A00

PeptideAtlas

More...
PeptideAtlasi
Q96A00

PRoteomics IDEntifications database

More...
PRIDEi
Q96A00

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
75885 [Q96A00-1]
75886 [Q96A00-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q96A00

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q96A00

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Isoform 1 is detected in aorta and testis. Isoform 2 is detected in aorta.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000167641 Expressed in 173 organ(s), highest expression level in popliteal artery

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q96A00 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q96A00 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
CAB005044
CAB009803
HPA042097
HPA054534

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
125153, 19 interactors

Protein interaction database and analysis system

More...
IntActi
Q96A00, 2 interactors

Molecular INTeraction database

More...
MINTi
Q96A00

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000301242

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q96A00

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni35 – 120InhibitoryAdd BLAST86

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the PP1 inhibitor family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IZE6 Eukaryota
ENOG4111Q1J LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000182985

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000231993

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q96A00

KEGG Orthology (KO)

More...
KOi
K12328

Identification of Orthologs from Complete Genome Data

More...
OMAi
VEKWIDC

Database of Orthologous Groups

More...
OrthoDBi
1492626at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q96A00

TreeFam database of animal gene trees

More...
TreeFami
TF105546

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.150.220, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR008025 CPI-17
IPR036658 CPI-17_sf

The PANTHER Classification System

More...
PANTHERi
PTHR16188 PTHR16188, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF05361 PP1_inhibitor, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF81790 SSF81790, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 3 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q96A00-1) [UniParc]FASTAAdd to basket
Also known as: CPI-17alpha

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MAAQRLGKRV LSKLQSPSRA RGPGGSPGGL QKRHARVTVK YDRRELQRRL
60 70 80 90 100
DVEKWIDGRL EELYRGMEAD MPDEINIDEL LELESEEERS RKIQGLLKSC
110 120 130 140
GKPVEDFIQE LLAKLQGLHR QPGLRQPSPS HDGSLSPLQD RARTAHP
Length:147
Mass (Da):16,693
Last modified:December 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i470EE2C082FF7319
GO
Isoform 2 (identifier: Q96A00-2) [UniParc]FASTAAdd to basket
Also known as: CPI-17beta

The sequence of this isoform differs from the canonical sequence as follows:
     68-94: Missing.

Show »
Length:120
Mass (Da):13,480
Checksum:iB729738ABCE93AC5
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
K7EMN0K7EMN0_HUMAN
Protein phosphatase 1 regulatory su...
PPP1R14A
123Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
K7EJB8K7EJB8_HUMAN
Protein phosphatase 1 regulatory su...
PPP1R14A
121Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0B4J2A3A0A0B4J2A3_HUMAN
Protein phosphatase 1 regulatory su...
PPP1R14A
77Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti123G → R in AAP97242 (Ref. 2) Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_01184168 – 94Missing in isoform 2. 1 PublicationAdd BLAST27

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB056508 mRNA Translation: BAB62502.1
AB056509 mRNA Translation: BAB62503.1
AF123763 mRNA Translation: AAP97242.1
AY050668 Genomic DNA Translation: AAL24445.1
AY050670 mRNA Translation: AAL25828.1
BC021089 mRNA Translation: AAH21089.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS12509.1 [Q96A00-1]
CCDS58660.1 [Q96A00-2]

Protein sequence database of the Protein Information Resource

More...
PIRi
JC7719

NCBI Reference Sequences

More...
RefSeqi
NP_001230876.1, NM_001243947.1 [Q96A00-2]
NP_150281.1, NM_033256.2 [Q96A00-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000301242; ENSP00000301242; ENSG00000167641 [Q96A00-1]
ENST00000347262; ENSP00000301243; ENSG00000167641 [Q96A00-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
94274

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:94274

UCSC genome browser

More...
UCSCi
uc002ohq.3 human [Q96A00-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB056508 mRNA Translation: BAB62502.1
AB056509 mRNA Translation: BAB62503.1
AF123763 mRNA Translation: AAP97242.1
AY050668 Genomic DNA Translation: AAL24445.1
AY050670 mRNA Translation: AAL25828.1
BC021089 mRNA Translation: AAH21089.1
CCDSiCCDS12509.1 [Q96A00-1]
CCDS58660.1 [Q96A00-2]
PIRiJC7719
RefSeqiNP_001230876.1, NM_001243947.1 [Q96A00-2]
NP_150281.1, NM_033256.2 [Q96A00-1]

3D structure databases

SMRiQ96A00
ModBaseiSearch...

Protein-protein interaction databases

BioGridi125153, 19 interactors
IntActiQ96A00, 2 interactors
MINTiQ96A00
STRINGi9606.ENSP00000301242

PTM databases

iPTMnetiQ96A00
PhosphoSitePlusiQ96A00

Polymorphism and mutation databases

BioMutaiPPP1R14A
DMDMi55583974

Proteomic databases

EPDiQ96A00
jPOSTiQ96A00
MassIVEiQ96A00
MaxQBiQ96A00
PaxDbiQ96A00
PeptideAtlasiQ96A00
PRIDEiQ96A00
ProteomicsDBi75885 [Q96A00-1]
75886 [Q96A00-2]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
94274

Genome annotation databases

EnsembliENST00000301242; ENSP00000301242; ENSG00000167641 [Q96A00-1]
ENST00000347262; ENSP00000301243; ENSG00000167641 [Q96A00-2]
GeneIDi94274
KEGGihsa:94274
UCSCiuc002ohq.3 human [Q96A00-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
94274
DisGeNETi94274

GeneCards: human genes, protein and diseases

More...
GeneCardsi
PPP1R14A
HGNCiHGNC:14871 PPP1R14A
HPAiCAB005044
CAB009803
HPA042097
HPA054534
MIMi608153 gene
neXtProtiNX_Q96A00
OpenTargetsiENSG00000167641
PharmGKBiPA33623

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IZE6 Eukaryota
ENOG4111Q1J LUCA
GeneTreeiENSGT00950000182985
HOGENOMiHOG000231993
InParanoidiQ96A00
KOiK12328
OMAiVEKWIDC
OrthoDBi1492626at2759
PhylomeDBiQ96A00
TreeFamiTF105546

Enzyme and pathway databases

ReactomeiR-HSA-5625740 RHO GTPases activate PKNs
SIGNORiQ96A00

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
PPP1R14A human

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
PPP1R14A

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
94274
PharosiQ96A00

Protein Ontology

More...
PROi
PR:Q96A00

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000167641 Expressed in 173 organ(s), highest expression level in popliteal artery
ExpressionAtlasiQ96A00 baseline and differential
GenevisibleiQ96A00 HS

Family and domain databases

Gene3Di1.10.150.220, 1 hit
InterProiView protein in InterPro
IPR008025 CPI-17
IPR036658 CPI-17_sf
PANTHERiPTHR16188 PTHR16188, 1 hit
PfamiView protein in Pfam
PF05361 PP1_inhibitor, 1 hit
SUPFAMiSSF81790 SSF81790, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPP14A_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q96A00
Secondary accession number(s): Q7Z4X7, Q96S54
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 9, 2004
Last sequence update: December 1, 2001
Last modified: September 18, 2019
This is version 143 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
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