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Entry version 150 (18 Sep 2019)
Sequence version 1 (01 Dec 2001)
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Protein

Constitutive coactivator of peroxisome proliferator-activated receptor gamma

Gene

FAM120B

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Functions as a transactivator of PPARG and ESR1. Functions in adipogenesis through PPARG activation (By similarity).By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionActivator
Biological processDifferentiation, Transcription, Transcription regulation

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-1989781 PPARA activates gene expression
R-HSA-381340 Transcriptional regulation of white adipocyte differentiation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Constitutive coactivator of peroxisome proliferator-activated receptor gamma
Short name:
Constitutive coactivator of PPAR-gamma
Short name:
Constitutive coactivator of PPARG
Alternative name(s):
PPARG constitutive coactivator 1
Short name:
PGCC1
Protein FAM120B
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:FAM120B
Synonyms:CCPG, KIAA1838
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:21109 FAM120B

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
612266 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q96EK7

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
84498

Open Targets

More...
OpenTargetsi
ENSG00000112584

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134920525

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q96EK7

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
FAM120B

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74751843

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003329901 – 910Constitutive coactivator of peroxisome proliferator-activated receptor gammaAdd BLAST910

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei885Omega-N-methylarginineCombined sources1

Keywords - PTMi

Methylation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q96EK7

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q96EK7

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q96EK7

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q96EK7

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q96EK7

PeptideAtlas

More...
PeptideAtlasi
Q96EK7

PRoteomics IDEntifications database

More...
PRIDEi
Q96EK7

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
4505
76419 [Q96EK7-1]
76420 [Q96EK7-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q96EK7

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q96EK7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Widely expressed.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000112584 Expressed in 192 organ(s), highest expression level in testis

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q96EK7 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q96EK7 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA037518
HPA037519

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with ESR1 and RXRA.

Interacts with PPARG; in a ligand-independent manner (By similarity).

By similarity

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

WithEntry#Exp.IntActNotes
TRAF2Q129333EBI-739883,EBI-355744

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
124101, 12 interactors

Protein interaction database and analysis system

More...
IntActi
Q96EK7, 12 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000440125

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IGHB Eukaryota
ENOG410ZBE9 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00530000063168

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q96EK7

Database of Orthologous Groups

More...
OrthoDBi
203269at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q96EK7

TreeFam database of animal gene trees

More...
TreeFami
TF331093

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR026784 Coact_PPARg
IPR029060 PIN-like_dom_sf

The PANTHER Classification System

More...
PANTHERi
PTHR15976 PTHR15976, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF88723 SSF88723, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q96EK7-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MGVRGLQGFV GSTCPHICTV VNFKELAEHH RSKYPGCTPT IVVDAMCCLR
60 70 80 90 100
YWYTPESWIC GGQWREYFSA LRDFVKTFTA AGIKLIFFFD GMVEQDKRDE
110 120 130 140 150
WVKRRLKNNR EISRIFHYIK SHKEQPGRNM FFIPSGLAVF TRFALKTLGQ
160 170 180 190 200
ETLCSLQEAD YEVASYGLQH NCLGILGEDT DYLIYDTCPY FSISELCLES
210 220 230 240 250
LDTVMLCREK LCESLGLCVA DLPLLACLLG NDIIPEGMFE SFRYKCLSSY
260 270 280 290 300
TSVKENFDKK GNIILAVSDH ISKVLYLYQG EKKLEEILPL GPNKALFYKG
310 320 330 340 350
MASYLLPGQK SPWFFQKPKG VITLDKQVIS TSSDAESREE VPMCSDAESR
360 370 380 390 400
QEVPMCTGPE SRREVPVYTD SEPRQEVPMC SDPEPRQEVP TCTGPESRRE
410 420 430 440 450
VPMCSDPEPR QEVPMCTGPE ARQEVPMYTD SEPRQEVPMY TDSEPRQEVP
460 470 480 490 500
MYTGSEPRQE VPMYTGPESR QEVPMYTGPE SRQEVLIRTD PESRQEIMCT
510 520 530 540 550
GHESKQEVPI CTDPISKQED SMCTHAEINQ KLPVATDFEF KLEALMCTNP
560 570 580 590 600
EIKQEDPTNV GPEVKQQVTM VSDTEILKVA RTHHVQAESY LVYNIMSSGE
610 620 630 640 650
IECSNTLEDE LDQALPSQAF IYRPIRQRVY SLLLEDCQDV TSTCLAVKEW
660 670 680 690 700
FVYPGNPLRH PDLVRPLQMT IPGGTPSLKI LWLNQEPEIQ VRRLDTLLAC
710 720 730 740 750
FNLSSSREEL QAVESPFQAL CCLLIYLFVQ VDTLCLEDLH AFIAQALCLQ
760 770 780 790 800
GKSTSQLVNL QPDYINPRAV QLGSLLVRGL TTLVLVNSAC GFPWKTSDFM
810 820 830 840 850
PWNVFDGKLF HQKYLQSEKG YAVEVLLEQN RSRLTKFHNL KAVVCKACMK
860 870 880 890 900
ENRRITGRAH WGSHHAGRWG RQGSSYHRTG SGYSRSSQGQ PWRDQGPGSR
910
QYEHDQWRRY
Length:910
Mass (Da):103,783
Last modified:December 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i079F9385733B5FAC
GO
Isoform 2 (identifier: Q96EK7-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     762-764: PDY → VQT
     765-910: Missing.

Show »
Length:764
Mass (Da):86,878
Checksum:i3C059F20148DC432
GO
Isoform 3 (identifier: Q96EK7-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-668: Missing.

Note: No experimental confirmation available.
Show »
Length:242
Mass (Da):27,627
Checksum:i81DA1455D369ADCB
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F5GY05F5GY05_HUMAN
Constitutive coactivator of peroxis...
FAM120B
933Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0D9SEJ5A0A0D9SEJ5_HUMAN
Constitutive coactivator of peroxis...
FAM120B
922Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAB47467 differs from that shown. Reason: Erroneous initiation.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_043021370D → Y. Corresponds to variant dbSNP:rs6917485Ensembl.1
Natural variantiVAR_043022379M → T. Corresponds to variant dbSNP:rs6905356Ensembl.1
Natural variantiVAR_043023428Y → C. Corresponds to variant dbSNP:rs6900199Ensembl.1
Natural variantiVAR_043024430D → G. Corresponds to variant dbSNP:rs6900202Ensembl.1
Natural variantiVAR_043025431S → P. Corresponds to variant dbSNP:rs6905610Ensembl.1
Natural variantiVAR_043026433P → A. Corresponds to variant dbSNP:rs6934830Ensembl.1
Natural variantiVAR_043027440Y → C. Corresponds to variant dbSNP:rs9366138Ensembl.1
Natural variantiVAR_043028511C → G. Corresponds to variant dbSNP:rs9348266Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0552671 – 668Missing in isoform 3. 1 PublicationAdd BLAST668
Alternative sequenceiVSP_033415762 – 764PDY → VQT in isoform 2. 1 Publication3
Alternative sequenceiVSP_033416765 – 910Missing in isoform 2. 1 PublicationAdd BLAST146

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
DQ873695 mRNA Translation: ABH09086.1
AB058741 mRNA Translation: BAB47467.1 Different initiation.
AK296825 mRNA Translation: BAG59396.1
AL008628 Genomic DNA No translation available.
AL078605 Genomic DNA No translation available.
CH471051 Genomic DNA Translation: EAW47424.1
BC012177 mRNA Translation: AAH12177.1
AY266458 mRNA Translation: AAP31032.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS5314.1 [Q96EK7-1]
CCDS69243.1 [Q96EK7-3]

NCBI Reference Sequences

More...
RefSeqi
NP_001273310.1, NM_001286381.1 [Q96EK7-3]
NP_115824.1, NM_032448.2 [Q96EK7-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000476287; ENSP00000417970; ENSG00000112584 [Q96EK7-1]
ENST00000616072; ENSP00000482544; ENSG00000275333 [Q96EK7-3]
ENST00000617082; ENSP00000481344; ENSG00000275333 [Q96EK7-1]
ENST00000625626; ENSP00000485793; ENSG00000112584 [Q96EK7-3]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
84498

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:84498

UCSC genome browser

More...
UCSCi
uc003qxp.5 human [Q96EK7-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ873695 mRNA Translation: ABH09086.1
AB058741 mRNA Translation: BAB47467.1 Different initiation.
AK296825 mRNA Translation: BAG59396.1
AL008628 Genomic DNA No translation available.
AL078605 Genomic DNA No translation available.
CH471051 Genomic DNA Translation: EAW47424.1
BC012177 mRNA Translation: AAH12177.1
AY266458 mRNA Translation: AAP31032.1
CCDSiCCDS5314.1 [Q96EK7-1]
CCDS69243.1 [Q96EK7-3]
RefSeqiNP_001273310.1, NM_001286381.1 [Q96EK7-3]
NP_115824.1, NM_032448.2 [Q96EK7-1]

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGridi124101, 12 interactors
IntActiQ96EK7, 12 interactors
STRINGi9606.ENSP00000440125

PTM databases

iPTMnetiQ96EK7
PhosphoSitePlusiQ96EK7

Polymorphism and mutation databases

BioMutaiFAM120B
DMDMi74751843

Proteomic databases

EPDiQ96EK7
jPOSTiQ96EK7
MassIVEiQ96EK7
MaxQBiQ96EK7
PaxDbiQ96EK7
PeptideAtlasiQ96EK7
PRIDEiQ96EK7
ProteomicsDBi4505
76419 [Q96EK7-1]
76420 [Q96EK7-2]

Genome annotation databases

EnsembliENST00000476287; ENSP00000417970; ENSG00000112584 [Q96EK7-1]
ENST00000616072; ENSP00000482544; ENSG00000275333 [Q96EK7-3]
ENST00000617082; ENSP00000481344; ENSG00000275333 [Q96EK7-1]
ENST00000625626; ENSP00000485793; ENSG00000112584 [Q96EK7-3]
GeneIDi84498
KEGGihsa:84498
UCSCiuc003qxp.5 human [Q96EK7-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
84498
DisGeNETi84498

GeneCards: human genes, protein and diseases

More...
GeneCardsi
FAM120B
HGNCiHGNC:21109 FAM120B
HPAiHPA037518
HPA037519
MIMi612266 gene
neXtProtiNX_Q96EK7
OpenTargetsiENSG00000112584
PharmGKBiPA134920525

Human Unidentified Gene-Encoded large proteins database

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HUGEi
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GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiENOG410IGHB Eukaryota
ENOG410ZBE9 LUCA
GeneTreeiENSGT00530000063168
InParanoidiQ96EK7
OrthoDBi203269at2759
PhylomeDBiQ96EK7
TreeFamiTF331093

Enzyme and pathway databases

ReactomeiR-HSA-1989781 PPARA activates gene expression
R-HSA-381340 Transcriptional regulation of white adipocyte differentiation

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
FAM120B human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
84498
PharosiQ96EK7

Protein Ontology

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PROi
PR:Q96EK7

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000112584 Expressed in 192 organ(s), highest expression level in testis
ExpressionAtlasiQ96EK7 baseline and differential
GenevisibleiQ96EK7 HS

Family and domain databases

InterProiView protein in InterPro
IPR026784 Coact_PPARg
IPR029060 PIN-like_dom_sf
PANTHERiPTHR15976 PTHR15976, 1 hit
SUPFAMiSSF88723 SSF88723, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF120B_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q96EK7
Secondary accession number(s): B4DL34, Q86V68, Q96JI9
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: December 1, 2001
Last modified: September 18, 2019
This is version 150 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 6
    Human chromosome 6: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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