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1 to 25 of 36  Show
  1. 11
    "Glutamate carboxypeptidase II gene expression in the human frontal and temporal lobe in schizophrenia."
    Ghose S., Weickert C.S., Colvin S.M., Coyle J.T., Herman M.M., Hyde T.M., Kleinman J.E.
    Neuropsychopharmacology 29:117-125(2004) [PubMed] [Europe PMC] [Abstract]
    Category: Expression, Sequences.
    Annotation: GCP II mRNA was detected in glial cells. Glial-rich regions specifically the DLPFC and ERC white matter and the molecular and polymorphic layers in the hippocampus express high levels of GCP II mRNA.
    Source: GeneRIF:84735.

    This publication is mapped to 2 other entries.

  2. 12
    "Allelic variation in the CNDP1 gene and its lack of association with longevity and coronary heart disease."
    Zschocke J., Nebel A., Wicks K., Peters V., El Mokhtari N.E., Krawczak M., van der Woude F., Janssen B., Schreiber S.
    Mech. Ageing Dev. 127:817-820(2006) [PubMed] [Europe PMC] [Abstract]
    Category: Pathology & Biotech, Sequences.
    Annotation: Observational study of gene-disease association. (HuGE Navigator); no difference in allele or genotype frequency between centenarians & controls or between cardiovascular patients & controls; the recently identified functional carnosinase variant does not contribute to longevity or protect against coronary heart disease. [GeneRIF:84735]. Not Associated with CARDIOVASCULAR: atherosclerosis, coronary longevity. [GAD:145600].
    Source: GAD:145600, GeneRIF:84735.

    This publication is mapped to 2 other entries.

  3. 13
    "Identification of carboxypeptidase of glutamate like-B as a candidate suppressor in cell growth and metastasis in human hepatocellular carcinoma."
    Zhang P., Chan D.W., Zhu Y., Li J.J., Ng I.-O., Wan D., Gu J.
    Clin. Cancer Res. 12:6617-6625(2006) [PubMed] [Europe PMC] [Abstract]
    Category: Expression, Sequences.
    Annotation: CPGL-B may be associated with cell growth and metastasis of HCC.
    Source: GeneRIF:84735.

    This publication is mapped to 2 other entries.

  4. 14
    "A leucine repeat in the carnosinase gene CNDP1 is associated with diabetic end-stage renal disease in European Americans."
    Freedman B.I., Hicks P.J., Sale M.M., Pierson E.D., Langefeld C.D., Rich S.S., Xu J., McDonough C., Janssen B., Yard B.A., van der Woude F.J., Bowden D.W.
    Nephrol. Dial. Transplant. 22:1131-1135(2007) [PubMed] [Europe PMC] [Abstract]
    Category: Pathology & Biotech, Sequences.
    Annotation: This replicates the CNDP1 gene association with diabetic nephropathy (DN) that was initially detected in European Caucasians and in Arabs and further demonstrates that the CNDP1 gene and carnosine pathway appear to play a role in susceptibility to DN; Observational study of gene-disease association. (HuGE Navigator). [GeneRIF:84735]. Associated with METABOLIC: diabetes, type 2 kidney failure, chronic. [GAD:145601].
    Source: GAD:145601, GeneRIF:84735.

    This publication is mapped to 2 other entries.

  5. 15
    "A CTG polymorphism in the CNDP1 gene determines the secretion of serum carnosinase in Cos-7 transfected cells."
    Riedl E., Koeppel H., Brinkkoetter P., Sternik P., Steinbeisser H., Sauerhoefer S., Janssen B., van der Woude F.J., Yard B.A.
    Diabetes 56:2410-2413(2007) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Annotation: Diabetic patients homozygous for CNDP1 are protected against diabetic nephropathy.
    Source: GeneRIF:84735.

    This publication is mapped to 2 other entries.

  6. 16
    Category: Pathology & Biotech, Sequences.
    Annotation: CN1-dependent susceptibility to diabetic nephropathy may at least in part be mediated by altered glucose metabolism in type 2 diabetic patients.
    Source: GeneRIF:84735.

    This publication is mapped to 8 other entries.

  7. 17
    "Exclusion of polymorphisms in carnosinase genes (CNDP1 and CNDP2) as a cause of diabetic nephropathy in type 1 diabetes: results of large case-control and follow-up studies."
    Wanic K., Placha G., Dunn J., Smiles A., Warram J.H., Krolewski A.S.
    Diabetes 57:2547-2551(2008) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Annotation: Our large comprehensive study did not find an association between the D18S880 microsatellite or any other polymorphisms in the CNDP2-CNDP1 genomic region and susceptibility for diabetic nephropathy in type 1 diabetes; Observational study of gene-disease association. (HuGE Navigator).
    Source: GeneRIF:84735.

    This publication is mapped to 10 other entries.

  8. 18
    "The influence of carnosinase gene polymorphisms on diabetic nephropathy risk in African-Americans."
    McDonough C.W., Hicks P.J., Lu L., Langefeld C.D., Freedman B.I., Bowden D.W.
    Hum. Genet. 126:265-275(2009) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Annotation: Observational study of gene-disease association. (HuGE Navigator).
    Source: GeneRIF:84735.

    This publication is mapped to 10 other entries.

  9. 19
    Category: Pathology & Biotech, Sequences.
    Annotation: South Asian Surinamese have a lower frequency of the 5/5 homozygous genotype which was associated with lower carnosinase activity and genetic risk for developing diabetic nephropathy.
    Source: GeneRIF:84735.

    This publication is mapped to 2 other entries.

  10. 20
    "Genome-wide SNP genotyping study using pooled DNA to identify candidate markers mediating susceptibility to end-stage renal disease attributed to Type 1 diabetes."
    Craig D.W., Millis M.P., DiStefano J.K.
    Diabet. Med. 26:1090-1098(2009) [PubMed] [Europe PMC] [Abstract]
    Category: Pathology & Biotech.
    Annotation: Observational study and genome-wide association study of gene-disease association. (HuGE Navigator).
    Source: GeneRIF:84735.

    This publication is mapped to 42 other entries.

  11. 21
    "Examination of association with candidate genes for diabetic nephropathy in a Mexican American population."
    Kim S., Abboud H.E., Pahl M.V., Tayek J., Snyder S., Tamkin J., Alcorn H. Jr., Ipp E., Nast C.C., Elston R.C., Iyengar S.K., Adler S.G.
    Clin J Am Soc Nephrol 5:1072-1078(2010) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Annotation: Observational study of gene-disease association. (HuGE Navigator).
    Source: GeneRIF:84735.

    This publication is mapped to 30 other entries.

  12. 22
    Category: Pathology & Biotech, Sequences.
    Annotation: Association between the CNDP1 gene and diabetic nephropathy is sex specific and independent of susceptibility for type 2 diabetes; Observational study of gene-disease association. (HuGE Navigator).
    Source: GeneRIF:84735.

    This publication is mapped to 2 other entries.

  13. 23
    "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score."
    Rose J.E., Behm F.M., Drgon T., Johnson C., Uhl G.R.
    Mol. Med. 16:247-253(2010) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator).
    Source: GeneRIF:84735.

    This publication is mapped to 11682 other entries.

  14. 24
    "N-glycosylation of carnosinase influences protein secretion and enzyme activity: implications for hyperglycemia."
    Riedl E., Koeppel H., Pfister F., Peters V., Sauerhoefer S., Sternik P., Brinkkoetter P., Zentgraf H., Navis G., Henning R.H., Van Den Born J., Bakker S.J., Janssen B., van der Woude F.J., Yard B.A.
    Diabetes 59:1984-1990(2010) [PubMed] [Europe PMC] [Abstract]
    Category: Pathology & Biotech, PTM / Processing.
    Annotation: Hyperglycemia enhances CNDP1 secretion and enzyme activity; data suggest that poor blood glucose control in diabetic patients might result in an increased enzyme secretion even in the presence of the (CTG)(5) allele.
    Source: GeneRIF:84735.

    This publication is mapped to 2 other entries.

  15. 25
    "A polymorphism in the gene encoding carnosinase (CNDP1) as a predictor of mortality and progression from nephropathy to end-stage renal disease in type 1 diabetes mellitus."
    Alkhalaf A., Bakker S.J., Bilo H.J., Gans R.O., Navis G.J., Postmus D., Forsblom C., Groop P.H., Vionnet N., Hadjadj S., Marre M., Parving H.H., Rossing P., Tarnow L.
    Diabetologia 53:2562-2568(2010) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Annotation: Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator); CNDP1 polymorphism predicts progression to ESRD in patients with diabetic nephropathies but only late after baseline measurements.
    Source: GeneRIF:84735.

    This publication is mapped to 2 other entries.

  16. 26
    "Is carnosinase 1 gene (CNDP1) polymorphism associated with chronic kidney disease progression in children and young adults? results of a family-based study."
    Kilis-Pstrusinska K., Zwolinska D., Grzeszczak W.
    Arch. Med. Res. 41:356-362(2010) [PubMed] [Europe PMC] [Abstract]
    Category: Pathology & Biotech, Sequences.
    Annotation: Observational study of gene-disease association. (HuGE Navigator).
    Source: GeneRIF:84735.

    This publication is mapped to 2 other entries.

  17. 27
    "Vegetarianism, female gender and increasing age, but not CNDP1 genotype, are associated with reduced muscle carnosine levels in humans."
    Everaert I., Mooyaart A., Baguet A., Zutinic A., Baelde H., Achten E., Taes Y., De Heer E., Derave W.
    Amino Acids 40:1221-1229(2011) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Pathology & Biotech.
    Annotation: Observational study of gene-disease association. (HuGE Navigator); neither CNDP1 genotype nor the normal variation in circulating testosterone levels affects the muscular carnosine content.
    Source: GeneRIF:84735.

    This publication is mapped to 2 other entries.

  18. 28
    "Anserine inhibits carnosine degradation but in human serum carnosinase (CN1) is not correlated with histidine dipeptide concentration."
    Peters V., Jansen E.E., Jakobs C., Riedl E., Janssen B., Yard B.A., Wedel J., Hoffmann G.F., Zschocke J., Gotthardt D., Fischer C., Koppel H.
    Clin. Chim. Acta 412:263-267(2011) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: Serum histidine dipeptide concentrations are not correlated to serum carnosinase activity; Observational study of gene-disease association. (HuGE Navigator).
    Source: GeneRIF:84735.

    This publication is mapped to 2 other entries.

  19. 29
    "Relationship between carnosinase gene CNDP1 leucine repeat polymorphism and the clinical outcome of Chinese PD patients."
    Poon P.Y., Szeto C.C., Kwan B.C., Chow K.M., Li P.K.
    Clin. Nephrol. 74:343-345(2010) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Annotation: Observational study of gene-disease association. (HuGE Navigator); CTG polymorphism of the CNDP1 gene does not affect survival of Chinese peritoneal dialysis subjects.
    Source: GeneRIF:84735.

    This publication is mapped to 2 other entries.

  20. 30
    "Common variants in CNDP1 and CNDP2, and risk of nephropathy in type 2 diabetes."
    Ahluwalia T.S., Lindholm E., Groop L.C.
    Diabetologia 54:2295-2302(2011) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Annotation: Common variants in CNDP1 and CNDP2 play a role in susceptibility to kidney disease in patients with type 2 diabetes.
    Source: GeneRIF:84735.

    This publication is mapped to 10 other entries.

  21. 31
    Category: Sequences.
    Annotation: In this review correlations between serum carnosine and carnosinase activity and polymorphism in CNDP1 gene are analyzed. The role of CNDP1 gene polymorphism the development of diabetic nephropathy and non-diabetic chronic kidney disease is discussed.
    Source: GeneRIF:84735.

    This publication is mapped to 2 other entries.

  22. 32
    "Proteins with altered levels in plasma from glioblastoma patients as revealed by iTRAQ-based quantitative proteomic analysis."
    Gautam P., Nair S.C., Gupta M.K., Sharma R., Polisetty R.V., Uppin M.S., Sundaram C., Puligopu A.K., Ankathi P., Purohit A.K., Chandak G.R., Harsha H.C., Sirdeshmukh R.
    PLoS ONE 7:e46153-e46153(2012) [PubMed] [Europe PMC] [Abstract]
    Category: Expression.
    Annotation: Plasma levels of FLT and S100A9 proteins are up-regulated and CNDP1 levels are down-regulated in patients with glioblastoma.
    Source: GeneRIF:84735.

    This publication is mapped to 12 other entries.

  23. 33
    "The influence of a single nucleotide polymorphism within CNDP1 on susceptibility to diabetic nephropathy in Japanese women with type 2 diabetes."
    Kurashige M., Imamura M., Araki S., Suzuki D., Babazono T., Uzu T., Umezono T., Toyoda M., Kawai K., Imanishi M., Hanaoka K., Maegawa H., Uchigata Y., Hosoya T., Maeda S.
    PLoS ONE 8:e54064-e54064(2013) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Annotation: Rs12604675-A in CNDP1 may confer susceptibility to overt proteinuria in Japanese women with type 2 diabetes.
    Source: GeneRIF:84735.

    This publication is mapped to 2 other entries.

  24. 34
    "D18S880 microsatellite polymorphism of carnosinase gene and diabetic nephropathy: a meta-analysis."
    Zhu J.M., Wang B., Li J., Chen G.M., Fan Y.G., Feng C.C., Pan H.F., Ye D.Q.
    Genet Test Mol Biomarkers 17:289-294(2013) [PubMed] [Europe PMC] [Abstract]
    Category: Pathology & Biotech, Sequences.
    Annotation: This meta-analysis confirms that the carnosinase D18S880 microsatellite polymorphism is associated with daibetic nephropathy susceptibility especially in the type 2 DM and the Caucasian population.
    Source: GeneRIF:84735.

    This publication is mapped to 2 other entries.

  25. 35
    "Carnosinases, their substrates and diseases."
    Bellia F., Vecchio G., Rizzarelli E.
    Molecules 19:2299-2329(2014) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: Alterations of serum carnosinase (CN1) activity has been associated with several pathological conditions such as neurological disorders chronic diseases and cancer.
    Source: GeneRIF:84735.

    This publication is mapped to 2 other entries.

1 to 25 of 36  Show
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