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Entry version 139 (13 Nov 2019)
Sequence version 2 (18 May 2010)
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Protein

TIMELESS-interacting protein

Gene

TIPIN

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Important for cell survival after DNA damage or replication stress. May be specifically required for the ATR-CHEK1 pathway in the replication checkpoint induced by hydroxyurea or ultraviolet light. Forms a complex with TIMELESS and this complex regulates DNA replication processes under both normal and stress conditions, stabilizes replication forks and influences both CHEK1 phosphorylation and the intra-S phase checkpoint in response to genotoxic stress.3 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • DNA binding Source: GO_Central

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processCell cycle, Cell division, DNA damage, Mitosis

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-5693607 Processing of DNA double-strand break ends

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
TIMELESS-interacting protein
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TIPIN
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 15

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:30750 TIPIN

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
610716 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9BVW5

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
54962

Open Targets

More...
OpenTargetsi
ENSG00000075131

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA147357269

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9BVW5

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
TIPIN

Domain mapping of disease mutations (DMDM)

More...
DMDMi
296452932

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003052531 – 301TIMELESS-interacting proteinAdd BLAST301

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei194PhosphoserineCombined sources1
Modified residuei222PhosphoserineCombined sources1
Modified residuei233PhosphothreonineCombined sources1
Modified residuei244PhosphothreonineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9BVW5

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9BVW5

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9BVW5

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9BVW5

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9BVW5

PeptideAtlas

More...
PeptideAtlasi
Q9BVW5

PRoteomics IDEntifications database

More...
PRIDEi
Q9BVW5

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
79240

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9BVW5

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9BVW5

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000075131 Expressed in 187 organ(s), highest expression level in testis

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9BVW5 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9BVW5 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA039704
HPA058799

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with TIMELESS, which impairs TIMELESS self-association.

Interacts with RPA2, PRDX2, MCM6 and MCM7.

4 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
120300, 36 interactors

Database of interacting proteins

More...
DIPi
DIP-53658N

The Eukaryotic Linear Motif resource for Functional Sites in Proteins

More...
ELMi
Q9BVW5

Protein interaction database and analysis system

More...
IntActi
Q9BVW5, 27 interactors

Molecular INTeraction database

More...
MINTi
Q9BVW5

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000261881

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9BVW5

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni67 – 143Interaction with TIMELESSAdd BLAST77

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the CSM3 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3004 Eukaryota
ENOG4111VXN LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000005764

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000154594

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9BVW5

KEGG Orthology (KO)

More...
KOi
K10904

Identification of Orthologs from Complete Genome Data

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OMAi
NTPRAHT

Database of Orthologous Groups

More...
OrthoDBi
1505397at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9BVW5

TreeFam database of animal gene trees

More...
TreeFami
TF313290

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR012923 Csm3
IPR040038 TIPIN/Csm3/Swi3

The PANTHER Classification System

More...
PANTHERi
PTHR13220 PTHR13220, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF07962 Swi3, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

Q9BVW5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLEPQENGVI DLPDYEHVED ETFPPFPPPA SPERQDGEGT EPDEESGNGA
60 70 80 90 100
PVRVPPKRTV KRNIPKLDAQ RLISERGLPA LRHVFDKAKF KGKGHEAEDL
110 120 130 140 150
KMLIRHMEHW AHRLFPKLQF EDFIDRVEYL GSKKEVQTCL KRIRLDLPIL
160 170 180 190 200
HEDFVSNNDE VAENNEHDVT STELDPFLTN LSESEMFASE LSRSLTEEQQ
210 220 230 240 250
QRIERNKQLA LERRQAKLLS NSQTLGNDML MNTPRAHTVE EVNTDEDQKE
260 270 280 290 300
ESNGLNEDIL DNPCNDAIAN TLNEEETLLD QSFKNVQQQL DATSRNITEA

R
Length:301
Mass (Da):34,555
Last modified:May 18, 2010 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB0C69117A636CE3A
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H3BU04H3BU04_HUMAN
TIMELESS-interacting protein
TIPIN
294Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H3BTH1H3BTH1_HUMAN
TIMELESS-interacting protein
TIPIN
141Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H3BVG9H3BVG9_HUMAN
TIMELESS-interacting protein
TIPIN
116Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H3BQ83H3BQ83_HUMAN
TIMELESS-interacting protein
TIPIN
74Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti201Q → R in BAA91229 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_03519453R → P4 PublicationsCorresponds to variant dbSNP:rs9806123Ensembl.1
Natural variantiVAR_035195111A → G1 PublicationCorresponds to variant dbSNP:rs2063690Ensembl.1
Natural variantiVAR_053952260L → P. Corresponds to variant dbSNP:rs3759787Ensembl.1
Natural variantiVAR_035196267A → S1 PublicationCorresponds to variant dbSNP:rs3759786Ensembl.1
Natural variantiVAR_062207270N → D. Corresponds to variant dbSNP:rs34848112Ensembl.1
Natural variantiVAR_054483270N → S1 PublicationCorresponds to variant dbSNP:rs780014564Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK000523 mRNA Translation: BAA91229.1
EU551725 Genomic DNA Translation: ACB21044.1
AC055855 Genomic DNA No translation available.
CH471082 Genomic DNA Translation: EAW77762.1
BC000870 mRNA Translation: AAH00870.1
BK001386 mRNA Translation: DAA01365.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS10215.1

NCBI Reference Sequences

More...
RefSeqi
NP_001276915.1, NM_001289986.1
NP_060328.2, NM_017858.2
XP_005254578.1, XM_005254521.2
XP_005254579.1, XM_005254522.4
XP_006720657.1, XM_006720594.3
XP_011520045.1, XM_011521743.1
XP_016877879.1, XM_017022390.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000261881; ENSP00000261881; ENSG00000075131

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
54962

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:54962

UCSC genome browser

More...
UCSCi
uc002apr.3 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

<p>This subsection of the <a href="http://www.uniprot.org/manual/cross_references_section">Cross-references</a> section provides links to various web resources that are relevant for a specific protein.<p><a href='/help/web_resource' target='_top'>More...</a></p>Web resourcesi

NIEHS-SNPs

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK000523 mRNA Translation: BAA91229.1
EU551725 Genomic DNA Translation: ACB21044.1
AC055855 Genomic DNA No translation available.
CH471082 Genomic DNA Translation: EAW77762.1
BC000870 mRNA Translation: AAH00870.1
BK001386 mRNA Translation: DAA01365.1
CCDSiCCDS10215.1
RefSeqiNP_001276915.1, NM_001289986.1
NP_060328.2, NM_017858.2
XP_005254578.1, XM_005254521.2
XP_005254579.1, XM_005254522.4
XP_006720657.1, XM_006720594.3
XP_011520045.1, XM_011521743.1
XP_016877879.1, XM_017022390.1

3D structure databases

SMRiQ9BVW5
ModBaseiSearch...

Protein-protein interaction databases

BioGridi120300, 36 interactors
DIPiDIP-53658N
ELMiQ9BVW5
IntActiQ9BVW5, 27 interactors
MINTiQ9BVW5
STRINGi9606.ENSP00000261881

PTM databases

iPTMnetiQ9BVW5
PhosphoSitePlusiQ9BVW5

Polymorphism and mutation databases

BioMutaiTIPIN
DMDMi296452932

Proteomic databases

EPDiQ9BVW5
jPOSTiQ9BVW5
MassIVEiQ9BVW5
MaxQBiQ9BVW5
PaxDbiQ9BVW5
PeptideAtlasiQ9BVW5
PRIDEiQ9BVW5
ProteomicsDBi79240

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
54962

Genome annotation databases

EnsembliENST00000261881; ENSP00000261881; ENSG00000075131
GeneIDi54962
KEGGihsa:54962
UCSCiuc002apr.3 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
54962
DisGeNETi54962

GeneCards: human genes, protein and diseases

More...
GeneCardsi
TIPIN
HGNCiHGNC:30750 TIPIN
HPAiHPA039704
HPA058799
MIMi610716 gene
neXtProtiNX_Q9BVW5
OpenTargetsiENSG00000075131
PharmGKBiPA147357269

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG3004 Eukaryota
ENOG4111VXN LUCA
GeneTreeiENSGT00390000005764
HOGENOMiHOG000154594
InParanoidiQ9BVW5
KOiK10904
OMAiNTPRAHT
OrthoDBi1505397at2759
PhylomeDBiQ9BVW5
TreeFamiTF313290

Enzyme and pathway databases

ReactomeiR-HSA-5693607 Processing of DNA double-strand break ends

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
TIPIN human

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
TIPIN

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
54962
PharosiQ9BVW5

Protein Ontology

More...
PROi
PR:Q9BVW5

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000075131 Expressed in 187 organ(s), highest expression level in testis
ExpressionAtlasiQ9BVW5 baseline and differential
GenevisibleiQ9BVW5 HS

Family and domain databases

InterProiView protein in InterPro
IPR012923 Csm3
IPR040038 TIPIN/Csm3/Swi3
PANTHERiPTHR13220 PTHR13220, 1 hit
PfamiView protein in Pfam
PF07962 Swi3, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTIPIN_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9BVW5
Secondary accession number(s): B2CW64, Q9NWZ6
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 2, 2007
Last sequence update: May 18, 2010
Last modified: November 13, 2019
This is version 139 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 15
    Human chromosome 15: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. SIMILARITY comments
    Index of protein domains and families
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  5. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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