@base <http://purl.uniprot.org/uniprot/> .
@prefix annotation: <http://purl.uniprot.org/annotation/> .
@prefix citation: <http://purl.uniprot.org/citations/> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix disease: <http://purl.uniprot.org/diseases/> .
@prefix ECO: <http://purl.obolibrary.org/obo/ECO_> .
@prefix enzyme: <http://purl.uniprot.org/enzyme/> .
@prefix faldo: <http://biohackathon.org/resource/faldo#> .
@prefix foaf: <http://xmlns.com/foaf/0.1/> .
@prefix go: <http://purl.obolibrary.org/obo/GO_> .
@prefix isoform: <http://purl.uniprot.org/isoforms/> .
@prefix keyword: <http://purl.uniprot.org/keywords/> .
@prefix location: <http://purl.uniprot.org/locations/> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix position: <http://purl.uniprot.org/position/> .
@prefix pubmed: <http://purl.uniprot.org/pubmed/> .
@prefix range: <http://purl.uniprot.org/range/> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix taxon: <http://purl.uniprot.org/taxonomy/> .
@prefix tissue: <http://purl.uniprot.org/tissues/> .
@prefix up: <http://purl.uniprot.org/core/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
<Q9FKW3> rdf:type up:Protein ;
  up:reviewed true ;
  up:created "2007-09-11"^^xsd:date ;
  up:modified "2024-03-27"^^xsd:date ;
  up:version 119 ;
  up:mnemonic "CFI2_ARATH" ;
  up:replaces <Q1PDF7> ;
  up:citation citation:9679202 ,
    citation:27862469 ,
    citation:17147637 ;
  rdfs:seeAlso <http://purl.uniprot.org/embl-cds/BAB10427.1> ,
    <http://purl.uniprot.org/embl-cds/AED98184.1> ,
    <http://purl.uniprot.org/embl-cds/ABE66278.1> ,
    <http://purl.uniprot.org/refseq/NP_201423.2> ,
    <http://purl.uniprot.org/alphafolddb/Q9FKW3> ,
    <http://purl.uniprot.org/smr/Q9FKW3> ,
    <http://purl.uniprot.org/string/3702.Q9FKW3> ,
    <http://purl.uniprot.org/paxdb/3702-AT5G66230-2> ,
    <http://purl.uniprot.org/peptideatlas/Q9FKW3> ,
    <http://rdf.ebi.ac.uk/resource/ensembl.transcript/AT5G66220.1> ,
    <http://purl.uniprot.org/geneid/836754> ,
    <http://purl.uniprot.org/gramene/AT5G66220.1> ,
    <http://purl.uniprot.org/kegg/ath:AT5G66220> ,
    <http://purl.uniprot.org/araport/AT5G66220> ,
    <http://purl.uniprot.org/tair/AT5G66220> ,
    <http://purl.uniprot.org/eggnog/ENOG502QR7K> ,
    <http://purl.uniprot.org/inparanoid/Q9FKW3> ,
    <http://purl.uniprot.org/oma/VEFLHFP> ,
    <http://purl.uniprot.org/phylomedb/Q9FKW3> ,
    <http://purl.uniprot.org/biocyc/ARA:AT5G66220-MONOMER> ,
    <http://purl.obolibrary.org/obo/PR_Q9FKW3> ,
    <http://purl.uniprot.org/expressionatlas/Q9FKW3> ,
    <http://purl.uniprot.org/gene3d/1.10.890.20> ,
    <http://purl.uniprot.org/gene3d/3.50.70.10> ,
    <http://purl.uniprot.org/interpro/IPR044164> ,
    <http://purl.uniprot.org/interpro/IPR016087> ,
    <http://purl.uniprot.org/interpro/IPR016088> ,
    <http://purl.uniprot.org/interpro/IPR016089> ,
    <http://purl.uniprot.org/interpro/IPR036298> ,
    <http://purl.uniprot.org/panther/PTHR28039:SF8> ,
    <http://purl.uniprot.org/panther/PTHR28039> ,
    <http://purl.uniprot.org/pfam/PF02431> ,
    <http://purl.uniprot.org/supfam/SSF54626> ;
  up:recommendedName <Q9FKW3#SIP0427E226F4A7C754> ;
  up:enzyme enzyme:5.5.1.6 ;
  up:organism taxon:3702 ;
  up:encodedBy <Q9FKW3#gene-MD5C0D9614672BDAE0121D541A6E99EEFDD> ;
  up:annotation <Q9FKW3#SIPC6AFB18DD7A6D89B> ,
    <Q9FKW3#SIPA478D205CE8ED106> ,
    <Q9FKW3#SIPE2A8E6420B0D952C> ,
    <Q9FKW3#SIP234C4E94B461BF02> ,
    <Q9FKW3#SIPE5DB3F0F10C9DB55> ,
    <Q9FKW3#SIP09B776BAF5B53D7C> ,
    <Q9FKW3#SIPF16C2DFD2806A0CA> ,
    annotation:PRO_0000300831 ,
    <Q9FKW3#SIP5ED1F45BC1D22145> ,
    <Q9FKW3#SIP1D6E3BEB59244440> ,
    <Q9FKW3#SIPDFD78481DEF4207B> ,
    <Q9FKW3#SIP0A9553B49191165A> ,
    annotation:VSP_035545 ;
  up:existence up:Evidence_at_Transcript_Level_Existence ;
  up:classifiedWith keyword:25 ,
    keyword:284 ,
    keyword:413 ,
    keyword:1185 ,
    go:0045430 ,
    go:0009813 ;
  up:sequence isoform:Q9FKW3-1 ,
    isoform:Q9FKW3-2 ;
  up:attribution <Q9FKW3#attribution-59A7FCF25B58F62737E153EE799737E1> ,
    <Q9FKW3#attribution-29E984218F13346DF40D40BA4D897447> ,
    <Q9FKW3#attribution-21C63663A29AD55EE5E6908CFE1889D1> ,
    <Q9FKW3#attribution-3FDB23E504CE487C874384ADBF99229B> ,
    <Q9FKW3#attribution-1F1D235CEE6E9F517881B603655DF439> ;
  up:proteome <http://purl.uniprot.org/proteomes/UP000006548#Chromosome%205> .
citation:9679202 rdf:type up:Journal_Citation ;
  up:title "Structural analysis of Arabidopsis thaliana chromosome 5. V. Sequence features of the regions of 1,381,565 bp covered by twenty one physically assigned P1 and TAC clones." ;
  up:author "Kaneko T." ,
    "Kotani H." ,
    "Nakamura Y." ,
    "Sato S." ,
    "Asamizu E." ,
    "Miyajima N." ,
    "Tabata S." ;
  skos:exactMatch pubmed:9679202 ;
  foaf:primaryTopicOf <https://pubmed.ncbi.nlm.nih.gov/9679202> ;
  dcterms:identifier "doi:10.1093/dnares/5.2.131" ;
  up:date "1998"^^xsd:gYear ;
  up:name "DNA Res." ;
  up:volume "5" ;
  up:pages "131-145" .
<#_Q9FKW3-citation-9679202> rdf:type rdf:Statement ;
  rdf:subject <Q9FKW3> ;
  rdf:predicate up:citation ;
  rdf:object citation:9679202 ;
  rdf:type up:Citation_Statement ;
  up:scope "NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]" ;
  up:context <Q9FKW3#context-MD5ADB883A978082314F29DF549586CFC77> .
<Q9FKW3#context-MD5ADB883A978082314F29DF549586CFC77> rdf:type up:Strain ;
  rdfs:label "cv. Columbia" .
citation:27862469 rdf:type up:Journal_Citation ;
  up:title "Araport11: a complete reannotation of the Arabidopsis thaliana reference genome." ;
  up:author "Cheng C.Y." ,
    "Krishnakumar V." ,
    "Chan A.P." ,
    "Thibaud-Nissen F." ,
    "Schobel S." ,
    "Town C.D." ;
  skos:exactMatch pubmed:27862469 ;
  foaf:primaryTopicOf <https://pubmed.ncbi.nlm.nih.gov/27862469> ;
  dcterms:identifier "doi:10.1111/tpj.13415" ;
  up:date "2017"^^xsd:gYear ;
  up:name "Plant J." ;
  up:volume "89" ;
  up:pages "789-804" .
<#_Q9FKW3-citation-27862469> rdf:type rdf:Statement ;
  rdf:subject <Q9FKW3> ;
  rdf:predicate up:citation ;
  rdf:object citation:27862469 ;
  rdf:type up:Citation_Statement ;
  up:scope "GENOME REANNOTATION" ;
  up:context <Q9FKW3#context-MD5ADB883A978082314F29DF549586CFC77> .
citation:17147637 rdf:type up:Journal_Citation ;
  up:title "Simultaneous high-throughput recombinational cloning of open reading frames in closed and open configurations." ;
  up:author "Underwood B.A." ,
    "Vanderhaeghen R." ,
    "Whitford R." ,
    "Town C.D." ,
    "Hilson P." ;
  skos:exactMatch pubmed:17147637 ;
  foaf:primaryTopicOf <https://pubmed.ncbi.nlm.nih.gov/17147637> ;
  dcterms:identifier "doi:10.1111/j.1467-7652.2006.00183.x" ;
  up:date "2006"^^xsd:gYear ;
  up:name "Plant Biotechnol. J." ;
  up:volume "4" ;
  up:pages "317-324" .
<#_Q9FKW3-citation-17147637> rdf:type rdf:Statement ;
  rdf:subject <Q9FKW3> ;
  rdf:predicate up:citation ;
  rdf:object citation:17147637 ;
  rdf:type up:Citation_Statement ;
  up:scope "NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)" ;
  up:context <Q9FKW3#context-MD5ADB883A978082314F29DF549586CFC77> .
<http://purl.uniprot.org/embl-cds/BAB10427.1> rdf:type up:Nucleotide_Resource ;
  up:database <http://purl.uniprot.org/database/EMBL> ;
  up:locatedOn <http://purl.uniprot.org/embl/AB011474> .
<http://purl.uniprot.org/embl/AB011474> rdf:type up:Genomic_DNA .
<http://purl.uniprot.org/embl-cds/AED98184.1> rdf:type up:Nucleotide_Resource ;
  up:database <http://purl.uniprot.org/database/EMBL> ;
  up:locatedOn <http://purl.uniprot.org/embl/CP002688> .
<http://purl.uniprot.org/embl/CP002688> rdf:type up:Genomic_DNA .
<http://purl.uniprot.org/embl-cds/ABE66278.1> rdf:type up:Nucleotide_Resource ;
  up:database <http://purl.uniprot.org/database/EMBL> ;
  up:locatedOn <http://purl.uniprot.org/embl/DQ447111> .
<http://purl.uniprot.org/embl/DQ447111> rdf:type up:MRNA .
<http://purl.uniprot.org/refseq/NP_201423.2> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/RefSeq> ;
  up:translatedFrom <http://purl.uniprot.org/refseq/NM_126020.2#NP_201423.2_CDS> ;
  rdfs:seeAlso isoform:Q9FKW3-2 .
<http://purl.uniprot.org/refseq/NM_126020.2#NP_201423.2_CDS> up:locatedOn <http://purl.uniprot.org/refseq/NM_126020.2> .
<http://purl.uniprot.org/alphafolddb/Q9FKW3> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/AlphaFoldDB> .
<http://purl.uniprot.org/smr/Q9FKW3> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/SMR> .
<http://purl.uniprot.org/string/3702.Q9FKW3> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/STRING> .
<http://purl.uniprot.org/paxdb/3702-AT5G66230-2> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/PaxDb> .
<http://purl.uniprot.org/peptideatlas/Q9FKW3> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/PeptideAtlas> .
<http://rdf.ebi.ac.uk/resource/ensembl.transcript/AT5G66220.1> rdf:type up:Transcript_Resource ;
  up:database <http://purl.uniprot.org/database/EnsemblPlants> ;
  up:translatedTo <http://rdf.ebi.ac.uk/resource/ensembl.protein/AT5G66220.1> ;
  up:transcribedFrom <http://rdf.ebi.ac.uk/resource/ensembl/AT5G66220> ;
  rdfs:seeAlso isoform:Q9FKW3-2 .
<http://purl.uniprot.org/geneid/836754> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/GeneID> .
<http://purl.uniprot.org/gramene/AT5G66220.1> rdf:type up:Transcript_Resource ;
  up:database <http://purl.uniprot.org/database/Gramene> ;
  up:translatedTo <http://purl.uniprot.org/gramene/AT5G66220.1> ;
  up:transcribedFrom <http://purl.uniprot.org/gramene/AT5G66220> ;
  rdfs:seeAlso isoform:Q9FKW3-2 .
<http://purl.uniprot.org/kegg/ath:AT5G66220> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/KEGG> .
<http://purl.uniprot.org/araport/AT5G66220> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/Araport> .
<http://purl.uniprot.org/tair/AT5G66220> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/TAIR> .
<http://purl.uniprot.org/eggnog/ENOG502QR7K> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/eggNOG> ;
  rdfs:comment "Eukaryota" .
<http://purl.uniprot.org/inparanoid/Q9FKW3> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/InParanoid> .
<http://purl.uniprot.org/oma/VEFLHFP> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/OMA> .
<http://purl.uniprot.org/phylomedb/Q9FKW3> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/PhylomeDB> .
<http://purl.uniprot.org/biocyc/ARA:AT5G66220-MONOMER> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/BioCyc> .
<http://purl.obolibrary.org/obo/PR_Q9FKW3> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/PRO> .
<http://purl.uniprot.org/expressionatlas/Q9FKW3> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/ExpressionAtlas> ;
  rdfs:comment "baseline and differential" .
<http://purl.uniprot.org/gene3d/1.10.890.20> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/Gene3D> ;
  up:signatureSequenceMatch <http://purl.uniprot.org/isoforms/Q9FKW3-1#Gene3D_1.10.890.20_match_1> .
<http://purl.uniprot.org/gene3d/3.50.70.10> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/Gene3D> ;
  up:signatureSequenceMatch <http://purl.uniprot.org/isoforms/Q9FKW3-1#Gene3D_3.50.70.10_match_1> .
<http://purl.uniprot.org/interpro/IPR044164> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/InterPro> ;
  rdfs:comment "CFI" .
<http://purl.uniprot.org/interpro/IPR016087> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/InterPro> ;
  rdfs:comment "Chalcone_isomerase" .
<http://purl.uniprot.org/interpro/IPR016088> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/InterPro> ;
  rdfs:comment "Chalcone_isomerase_3-sand" .
<http://purl.uniprot.org/interpro/IPR016089> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/InterPro> ;
  rdfs:comment "Chalcone_isomerase_bundle_sf" .
<http://purl.uniprot.org/interpro/IPR036298> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/InterPro> ;
  rdfs:comment "Chalcone_isomerase_sf" .
<http://purl.uniprot.org/panther/PTHR28039:SF8> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/PANTHER> ;
  rdfs:comment "CHALCONE--FLAVANONE ISOMERASE 1-RELATED" ;
  up:signatureSequenceMatch <http://purl.uniprot.org/isoforms/Q9FKW3-1#PANTHER_PTHR28039:SF8_match_1> .
<http://purl.uniprot.org/panther/PTHR28039> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/PANTHER> ;
  rdfs:comment "CHALCONE--FLAVONONE ISOMERASE 1-RELATED" ;
  up:signatureSequenceMatch <http://purl.uniprot.org/isoforms/Q9FKW3-1#PANTHER_PTHR28039_match_1> .
<http://purl.uniprot.org/pfam/PF02431> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/Pfam> ;
  rdfs:comment "Chalcone" ;
  up:signatureSequenceMatch <http://purl.uniprot.org/isoforms/Q9FKW3-1#Pfam_PF02431_match_1> .
<http://purl.uniprot.org/supfam/SSF54626> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/SUPFAM> ;
  rdfs:comment "Chalcone isomerase" ;
  up:signatureSequenceMatch <http://purl.uniprot.org/isoforms/Q9FKW3-1#SUPFAM_SSF54626_match_1> .
<Q9FKW3#SIP0427E226F4A7C754> rdf:type up:Structured_Name ;
  up:fullName "Chalcone--flavanone isomerase 2" ;
  up:shortName "Chalcone isomerase 2" ;
  up:ecName "5.5.1.6" .
<Q9FKW3#gene-MD5C0D9614672BDAE0121D541A6E99EEFDD> rdf:type up:Gene ;
  skos:prefLabel "CHI2" ;
  up:locusName "At5g66220" ;
  up:orfName "K2A18.30" .
<Q9FKW3#SIPC6AFB18DD7A6D89B> rdf:type up:Function_Annotation ;
  rdfs:comment "Catalyzes the intramolecular cyclization of bicyclic chalcones into tricyclic (S)-flavanones. Responsible for the isomerization of 4,2',4',6'-tetrahydroxychalcone (also termed chalcone) into naringenin (By similarity)." .
<#_BA9FE8CF5597190B_rdfs.comment_551212DCEF69988C> rdf:type rdf:Statement ;
  rdf:subject <Q9FKW3#SIPC6AFB18DD7A6D89B> ;
  rdf:predicate rdfs:comment ;
  rdf:object "Catalyzes the intramolecular cyclization of bicyclic chalcones into tricyclic (S)-flavanones. Responsible for the isomerization of 4,2',4',6'-tetrahydroxychalcone (also termed chalcone) into naringenin (By similarity)." ;
  up:attribution <Q9FKW3#attribution-21C63663A29AD55EE5E6908CFE1889D1> .
<Q9FKW3#SIPA478D205CE8ED106> rdf:type up:Catalytic_Activity_Annotation ;
  up:catalyticActivity <Q9FKW3#SIP13BBB96EA8083BB0> .
<Q9FKW3#SIP13BBB96EA8083BB0> rdf:type up:Catalytic_Activity ;
  skos:closeMatch <http://purl.uniprot.org/enzyme/5.5.1.6#SIPFDF455B25211B557> ;
  up:enzymeClass enzyme:5.5.1.6 .
<Q9FKW3#SIPE2A8E6420B0D952C> rdf:type up:Pathway_Annotation ;
  rdfs:seeAlso <http://purl.uniprot.org/unipathway/464.154> .
<Q9FKW3#SIP234C4E94B461BF02> rdf:type up:Alternative_Splicing_Annotation ;
  up:sequence isoform:Q9FKW3-1 ,
    isoform:Q9FKW3-2 .
<Q9FKW3#SIPE5DB3F0F10C9DB55> rdf:type up:Annotation ;
  rdfs:comment "Part of the biosynthetic pathway for all classes of flavonoids, a large class of secondary plant metabolites, many of which are brightly colored." .
<Q9FKW3#SIP09B776BAF5B53D7C> rdf:type up:Annotation ;
  rdfs:comment "May be due to a competing acceptor splice site." ;
  up:sequence isoform:Q9FKW3-2 .
<#_43F093C1D0A5CD15_rdfs.comment_9B77F441C7460170> rdf:type rdf:Statement ;
  rdf:subject <Q9FKW3#SIP09B776BAF5B53D7C> ;
  rdf:predicate rdfs:comment ;
  rdf:object "May be due to a competing acceptor splice site." ;
  up:attribution <Q9FKW3#attribution-1F1D235CEE6E9F517881B603655DF439> .
<Q9FKW3#SIPF16C2DFD2806A0CA> rdf:type up:Similarity_Annotation ;
  rdfs:comment "Belongs to the chalcone isomerase family." .
<#_C5174A7F6852E078_rdfs.comment_7B8336F22417E29A> rdf:type rdf:Statement ;
  rdf:subject <Q9FKW3#SIPF16C2DFD2806A0CA> ;
  rdf:predicate rdfs:comment ;
  rdf:object "Belongs to the chalcone isomerase family." ;
  up:attribution <Q9FKW3#attribution-1F1D235CEE6E9F517881B603655DF439> .
annotation:PRO_0000300831 rdf:type up:Chain_Annotation ;
  rdfs:comment "Chalcone--flavanone isomerase 2" ;
  up:mass 24465 ;
  up:range range:22862447188063022tt1tt223 .
range:22862447188063022tt1tt223 rdf:type faldo:Region ;
  faldo:begin position:22862447188063022tt1 ;
  faldo:end position:22862447188063022tt223 .
position:22862447188063022tt1 rdf:type faldo:Position ,
    faldo:ExactPosition ;
  faldo:position 1 ;
  faldo:reference isoform:Q9FKW3-1 .
position:22862447188063022tt223 rdf:type faldo:Position ,
    faldo:ExactPosition ;
  faldo:position 223 ;
  faldo:reference isoform:Q9FKW3-1 .
<Q9FKW3#SIP5ED1F45BC1D22145> rdf:type up:Binding_Site_Annotation ;
  up:ligand <Q9FKW3#SIP6155B73171216805> ;
  up:range range:22862447188063022tt41tt41 .
range:22862447188063022tt41tt41 rdf:type faldo:Region ;
  faldo:begin position:22862447188063022tt41 ;
  faldo:end position:22862447188063022tt41 .
position:22862447188063022tt41 rdf:type faldo:Position ,
    faldo:ExactPosition ;
  faldo:position 41 ;
  faldo:reference isoform:Q9FKW3-1 .
<#_kb.Q9FKW3_up.annotation_01231335AC6B4C63> rdf:type rdf:Statement ;
  rdf:subject <Q9FKW3> ;
  rdf:predicate up:annotation ;
  rdf:object <Q9FKW3#SIP5ED1F45BC1D22145> ;
  up:attribution <Q9FKW3#attribution-21C63663A29AD55EE5E6908CFE1889D1> .
<Q9FKW3#SIP1D6E3BEB59244440> rdf:type up:Binding_Site_Annotation ;
  up:ligand <Q9FKW3#SIP6155B73171216805> ;
  up:range range:22862447188063022tt106tt106 .
range:22862447188063022tt106tt106 rdf:type faldo:Region ;
  faldo:begin position:22862447188063022tt106 ;
  faldo:end position:22862447188063022tt106 .
position:22862447188063022tt106 rdf:type faldo:Position ,
    faldo:ExactPosition ;
  faldo:position 106 ;
  faldo:reference isoform:Q9FKW3-1 .
<#_kb.Q9FKW3_up.annotation_FF484399FE16BF5C> rdf:type rdf:Statement ;
  rdf:subject <Q9FKW3> ;
  rdf:predicate up:annotation ;
  rdf:object <Q9FKW3#SIP1D6E3BEB59244440> ;
  up:attribution <Q9FKW3#attribution-21C63663A29AD55EE5E6908CFE1889D1> .
<Q9FKW3#SIPDFD78481DEF4207B> rdf:type up:Binding_Site_Annotation ;
  up:ligand <Q9FKW3#SIP6155B73171216805> ;
  up:range range:22862447188063022tt183tt183 .
range:22862447188063022tt183tt183 rdf:type faldo:Region ;
  faldo:begin position:22862447188063022tt183 ;
  faldo:end position:22862447188063022tt183 .
position:22862447188063022tt183 rdf:type faldo:Position ,
    faldo:ExactPosition ;
  faldo:position 183 ;
  faldo:reference isoform:Q9FKW3-1 .
<#_kb.Q9FKW3_up.annotation_F6FB355FE83020C5> rdf:type rdf:Statement ;
  rdf:subject <Q9FKW3> ;
  rdf:predicate up:annotation ;
  rdf:object <Q9FKW3#SIPDFD78481DEF4207B> ;
  up:attribution <Q9FKW3#attribution-21C63663A29AD55EE5E6908CFE1889D1> .
<Q9FKW3#SIP0A9553B49191165A> rdf:type up:Site_Annotation ;
  rdfs:comment "Important for catalytic activity" ;
  up:range range:22862447188063022tt99tt99 .
range:22862447188063022tt99tt99 rdf:type faldo:Region ;
  faldo:begin position:22862447188063022tt99 ;
  faldo:end position:22862447188063022tt99 .
position:22862447188063022tt99 rdf:type faldo:Position ,
    faldo:ExactPosition ;
  faldo:position 99 ;
  faldo:reference isoform:Q9FKW3-1 .
<#_kb.Q9FKW3_up.annotation_ECB99BD93DD5E826> rdf:type rdf:Statement ;
  rdf:subject <Q9FKW3> ;
  rdf:predicate up:annotation ;
  rdf:object <Q9FKW3#SIP0A9553B49191165A> ;
  up:attribution <Q9FKW3#attribution-21C63663A29AD55EE5E6908CFE1889D1> .
annotation:VSP_035545 rdf:type up:Alternative_Sequence_Annotation ;
  rdfs:comment "In isoform 2." ;
  up:substitution "" ;
  up:range range:22862447188063022tt1tt49 .
range:22862447188063022tt1tt49 rdf:type faldo:Region ;
  faldo:begin position:22862447188063022tt1 ;
  faldo:end position:22862447188063022tt49 .
position:22862447188063022tt49 rdf:type faldo:Position ,
    faldo:ExactPosition ;
  faldo:position 49 ;
  faldo:reference isoform:Q9FKW3-1 .
<#_kb.Q9FKW3_up.annotation_a.VSP_035545> rdf:type rdf:Statement ;
  rdf:subject <Q9FKW3> ;
  rdf:predicate up:annotation ;
  rdf:object annotation:VSP_035545 ;
  up:attribution <Q9FKW3#attribution-3FDB23E504CE487C874384ADBF99229B> .
<Q9FKW3#molecule_substrate> rdfs:label "substrate" .
<Q9FKW3#SIP6155B73171216805> rdfs:subClassOf <Q9FKW3#molecule_substrate> .
<#_kb.Q9FKW3_up.classifiedWith_obo.GO_0045430> rdf:type rdf:Statement ;
  rdf:subject <Q9FKW3> ;
  rdf:predicate up:classifiedWith ;
  rdf:object go:0045430 ;
  up:attribution <Q9FKW3#attribution-59A7FCF25B58F62737E153EE799737E1> .
<#_kb.Q9FKW3_up.classifiedWith_obo.GO_0009813> rdf:type rdf:Statement ;
  rdf:subject <Q9FKW3> ;
  rdf:predicate up:classifiedWith ;
  rdf:object go:0009813 ;
  up:attribution <Q9FKW3#attribution-29E984218F13346DF40D40BA4D897447> .
isoform:Q9FKW3-1 rdf:type up:Simple_Sequence ;
  up:modified "2001-03-01"^^xsd:date ;
  up:version 1 ;
  up:mass 24465 ;
  up:md5Checksum "b9feb38e8c7d1618a84f7b60166bfbfb" ;
  up:name "1" ;
  rdf:value "MPLPSVTPLHVDAFTFPPAVESPASHKRLFLGGAGKFVIVTVIGVYLEAMALPSISAKWKGKNAKELTESVPFFRQLVTGEFEKLARVTMKKRLTGIQYSEKVVENCEEIMKASGKYTRSEAKAIDQFLMVFKNQDFPPGSSIIFAICPKGSLTIAFSKEERVPKTGKAVIKNKLLGEAVLESMIGKNGVSPATRKSLAERLSKLMNKKDPYNEANVNVATKN" .
isoform:Q9FKW3-2 rdf:type up:Modified_Sequence ;
  up:name "2" ;
  up:basedOn isoform:Q9FKW3-1 ;
  rdf:value "MALPSISAKWKGKNAKELTESVPFFRQLVTGEFEKLARVTMKKRLTGIQYSEKVVENCEEIMKASGKYTRSEAKAIDQFLMVFKNQDFPPGSSIIFAICPKGSLTIAFSKEERVPKTGKAVIKNKLLGEAVLESMIGKNGVSPATRKSLAERLSKLMNKKDPYNEANVNVATKN" ;
  up:modification annotation:VSP_035545 .
<Q9FKW3#attribution-59A7FCF25B58F62737E153EE799737E1> dcterms:creator <http://purl.uniprot.org/goa-projects/UniProtKB-EC> ;
  up:evidence ECO:0007669 .
<Q9FKW3#attribution-29E984218F13346DF40D40BA4D897447> dcterms:creator <http://purl.uniprot.org/goa-projects/UniProtKB-UniPathway> ;
  up:evidence ECO:0007669 .
<Q9FKW3#attribution-21C63663A29AD55EE5E6908CFE1889D1> up:manual true ;
  up:evidence ECO:0000250 .
<Q9FKW3#attribution-3FDB23E504CE487C874384ADBF99229B> up:manual true ;
  up:evidence ECO:0000303 ;
  up:source citation:17147637 .
<Q9FKW3#attribution-1F1D235CEE6E9F517881B603655DF439> up:manual true ;
  up:evidence ECO:0000305 .