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Entry version 150 (31 Jul 2019)
Sequence version 1 (01 Mar 2001)
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Protein

ESF1 homolog

Gene

ESF1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May constitute a novel regulatory system for basal transcription. Negatively regulates ABT1 (By similarity).By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

  • rRNA processing Source: GO_Central

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processTranscription, Transcription regulation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
ESF1 homolog
Alternative name(s):
ABT1-associated protein
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ESF1
Synonyms:ABTAP, C20orf6
ORF Names:HDCMC28P
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 20

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:15898 ESF1

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9H501

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
51575

Open Targets

More...
OpenTargetsi
ENSG00000089048

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162385420

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ESF1

Domain mapping of disease mutations (DMDM)

More...
DMDMi
25452905

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemovedCombined sources
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000794102 – 851ESF1 homologAdd BLAST850

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei2N-acetylserineCombined sources1
Modified residuei75PhosphoserineCombined sources1
Modified residuei77PhosphoserineCombined sources1
Modified residuei79PhosphoserineCombined sources1
Modified residuei82PhosphoserineCombined sources1
Modified residuei134PhosphoserineCombined sources1
Modified residuei153PhosphoserineCombined sources1
Modified residuei179PhosphoserineCombined sources1
Modified residuei180PhosphoserineCombined sources1
Modified residuei198PhosphoserineCombined sources1
Modified residuei296PhosphoserineCombined sources1
Modified residuei298PhosphoserineCombined sources1
Modified residuei311PhosphothreonineCombined sources1
Modified residuei312PhosphoserineCombined sources1
Modified residuei313PhosphoserineCombined sources1
Modified residuei614PhosphoserineCombined sources1
Modified residuei657PhosphoserineCombined sources1
Modified residuei663PhosphoserineCombined sources1
Modified residuei693PhosphothreonineCombined sources1
Modified residuei694PhosphoserineCombined sources1
Modified residuei735PhosphoserineCombined sources1
Modified residuei823PhosphoserineCombined sources1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

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EPDi
Q9H501

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9H501

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9H501

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9H501

PeptideAtlas

More...
PeptideAtlasi
Q9H501

PRoteomics IDEntifications database

More...
PRIDEi
Q9H501

ProteomicsDB human proteome resource

More...
ProteomicsDBi
80886

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9H501

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9H501

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000089048 Expressed in 235 organ(s), highest expression level in secondary oocyte

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9H501 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9H501 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA047083
HPA050396

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with ABT1.

Forms a complex with ABT1 and suppresses the ABT1-induced activation of polymerase II-directed transcription in mammalian cells (By similarity).

By similarity

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
119620, 35 interactors

Protein interaction database and analysis system

More...
IntActi
Q9H501, 23 interactors

Molecular INTeraction database

More...
MINTi
Q9H501

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000202816

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9H501

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili730 – 824Sequence analysisAdd BLAST95

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi87 – 170Lys-richAdd BLAST84
Compositional biasi268 – 321Asp-richAdd BLAST54
Compositional biasi567 – 851Lys-richAdd BLAST285

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the ESF1 family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2318 Eukaryota
COG5638 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000004881

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000182523

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9H501

Identification of Orthologs from Complete Genome Data

More...
OMAi
LTWDETA

Database of Orthologous Groups

More...
OrthoDBi
1300279at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9H501

TreeFam database of animal gene trees

More...
TreeFami
TF105822

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR039754 Esf1
IPR012580 NUC153

The PANTHER Classification System

More...
PANTHERi
PTHR12202 PTHR12202, 2 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF08159 NUC153, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q9H501-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSSKQEIMSD QRFRRVAKDP RFWEMPEKDR KVKIDKRFRA MFHDKKFKLN
60 70 80 90 100
YAVDKRGRPI SHSTTEDLKR FYDLSDSDSN LSGEDSKALS QKKIKKKKTQ
110 120 130 140 150
TKKEIDSKNL VEKKKETKKA NHKGSENKTD LDNSIGIKKM KTSCKFKIDS
160 170 180 190 200
NISPKKDSKE FTQKNKKEKK NIVQHTTDSS LEEKQRTLDS GTSEIVKSPR
210 220 230 240 250
IECSKTRREM QSVVQLIMTR DSDGYENSTD GEMCDKDALE EDSESVSEIG
260 270 280 290 300
SDEESENEIT SVGRASGDDD GSEDDEEEDE DEEEDEDEDS EDDDKSDSGP
310 320 330 340 350
DLARGKGNIE TSSEDEDDTA DLFPEESGFE HAWRELDKDA PRADEITRRL
360 370 380 390 400
AVCNMDWDRL KAKDLLALFN SFKPKGGVIF SVKIYPSEFG KERMKEEQVQ
410 420 430 440 450
GPVELLSIPE DAPEKDWTSR EKLRDYQFKR LKYYYAVVDC DSPETASKIY
460 470 480 490 500
EDCDGLEFES SCSFIDLRFI PDDITFDDEP KDVASEVNLT AYKPKYFTSA
510 520 530 540 550
AMGTSTVEIT WDETDHERIT MLNRKFKKEE LLDMDFQAYL ASSSEDEEEI
560 570 580 590 600
EEELQGDDGV NVEEDGKTKK SQKDDEEQIA KYRQLLQVIQ EKEKKGKEND
610 620 630 640 650
MEMEIKWVPG LKESAEEMVK NKLEGKDKLT PWEQFLEKKK EKKRLKRKQK
660 670 680 690 700
ALAEEASEEE LPSDVDLNDP YFAEEVKQIG INKKSVKSAK DGTSPEEEIE
710 720 730 740 750
IERQKAEMAL LMMDEDEDSK KHFNYNKIVE HQNLSKKKKK QLMKKKELIE
760 770 780 790 800
DDFEVNVNDA RFQAMYTSHL FNLDPSDPNF KKTKAMEKIL EEKARQRERK
810 820 830 840 850
EQELTQAIKK KESEIEKESQ RKSIDPALSM LIKSIKTKTE QFQARKKQKV

K
Length:851
Mass (Da):98,796
Last modified:March 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i1BA283E7A0A65432
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A087WX71A0A087WX71_HUMAN
ESF1 homolog
ESF1
456Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAF65504 differs from that shown. Reason: Frameshift at position 664.Curated
The sequence BAA91123 differs from that shown. Contaminating sequence. Potential poly-A sequence.Curated
The sequence BAB14167 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti186R → K in AAF65504 (Ref. 4) Curated1
Sequence conflicti198S → T in BAB14023 (PubMed:14702039).Curated1
Sequence conflicti228S → P in BAA91123 (PubMed:14702039).Curated1
Sequence conflicti298S → G in AAF65504 (Ref. 4) Curated1
Sequence conflicti336L → S in BAA91123 (PubMed:14702039).Curated1
Sequence conflicti351A → V in AAF65504 (Ref. 4) Curated1
Sequence conflicti390G → R in AAF65504 (Ref. 4) Curated1
Sequence conflicti469F → Y in AAF65504 (Ref. 4) Curated1
Sequence conflicti474I → V in BAA91123 (PubMed:14702039).Curated1
Sequence conflicti483V → A in AAF65504 (Ref. 4) Curated1
Sequence conflicti514T → S in BAB14023 (PubMed:14702039).Curated1
Sequence conflicti593E → K in AAH46107 (PubMed:15489334).Curated1
Sequence conflicti829S → P in BAB14167 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_053082386P → L. Corresponds to variant dbSNP:rs6079171Ensembl.1
Natural variantiVAR_024331550I → T2 PublicationsCorresponds to variant dbSNP:rs3180370Ensembl.1
Natural variantiVAR_053083824I → L. Corresponds to variant dbSNP:rs34414644Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AL161659 Genomic DNA No translation available.
AK000375 mRNA Translation: BAA91123.1 Sequence problems.
AK022369 mRNA Translation: BAB14023.1
AK022670 mRNA Translation: BAB14167.1 Different initiation.
BC046107 mRNA Translation: AAH46107.1
AF068285 mRNA Translation: AAF65504.1 Frameshift.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS13117.1

NCBI Reference Sequences

More...
RefSeqi
NP_001263309.1, NM_001276380.1
NP_057733.2, NM_016649.3
XP_016883363.1, XM_017027874.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000202816; ENSP00000202816; ENSG00000089048

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
51575

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:51575

UCSC genome browser

More...
UCSCi
uc002woj.3 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL161659 Genomic DNA No translation available.
AK000375 mRNA Translation: BAA91123.1 Sequence problems.
AK022369 mRNA Translation: BAB14023.1
AK022670 mRNA Translation: BAB14167.1 Different initiation.
BC046107 mRNA Translation: AAH46107.1
AF068285 mRNA Translation: AAF65504.1 Frameshift.
CCDSiCCDS13117.1
RefSeqiNP_001263309.1, NM_001276380.1
NP_057733.2, NM_016649.3
XP_016883363.1, XM_017027874.1

3D structure databases

SMRiQ9H501
ModBaseiSearch...

Protein-protein interaction databases

BioGridi119620, 35 interactors
IntActiQ9H501, 23 interactors
MINTiQ9H501
STRINGi9606.ENSP00000202816

PTM databases

iPTMnetiQ9H501
PhosphoSitePlusiQ9H501

Polymorphism and mutation databases

BioMutaiESF1
DMDMi25452905

Proteomic databases

EPDiQ9H501
jPOSTiQ9H501
MaxQBiQ9H501
PaxDbiQ9H501
PeptideAtlasiQ9H501
PRIDEiQ9H501
ProteomicsDBi80886

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
51575
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000202816; ENSP00000202816; ENSG00000089048
GeneIDi51575
KEGGihsa:51575
UCSCiuc002woj.3 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
51575
DisGeNETi51575

GeneCards: human genes, protein and diseases

More...
GeneCardsi
ESF1
HGNCiHGNC:15898 ESF1
HPAiHPA047083
HPA050396
neXtProtiNX_Q9H501
OpenTargetsiENSG00000089048
PharmGKBiPA162385420

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG2318 Eukaryota
COG5638 LUCA
GeneTreeiENSGT00390000004881
HOGENOMiHOG000182523
InParanoidiQ9H501
OMAiLTWDETA
OrthoDBi1300279at2759
PhylomeDBiQ9H501
TreeFamiTF105822

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
ESF1 human

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
ESF1

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
51575

Protein Ontology

More...
PROi
PR:Q9H501

Gene expression databases

BgeeiENSG00000089048 Expressed in 235 organ(s), highest expression level in secondary oocyte
ExpressionAtlasiQ9H501 baseline and differential
GenevisibleiQ9H501 HS

Family and domain databases

InterProiView protein in InterPro
IPR039754 Esf1
IPR012580 NUC153
PANTHERiPTHR12202 PTHR12202, 2 hits
PfamiView protein in Pfam
PF08159 NUC153, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiESF1_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9H501
Secondary accession number(s): Q86X92
, Q9H9Q5, Q9HA35, Q9NX93, Q9P1S6
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 25, 2002
Last sequence update: March 1, 2001
Last modified: July 31, 2019
This is version 150 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 20
    Human chromosome 20: entries, gene names and cross-references to MIM
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
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