Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 136 (18 Sep 2019)
Sequence version 2 (25 Jul 2006)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein

Actin-related protein 5

Gene

ACTR5

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. Involved in DNA double-strand break repair and UV-damage excision repair.2 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processDNA damage, DNA recombination, DNA repair, Transcription, Transcription regulation

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-5689603 UCH proteinases
R-HSA-5696394 DNA Damage Recognition in GG-NER

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...
SignaLinki
Q9H9F9

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Actin-related protein 5
Short name:
hARP5
Alternative name(s):
Sarcoma antigen NY-SAR-16
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ACTR5
Synonyms:ARP5
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 20

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:14671 ACTR5

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9H9F9

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
79913

Open Targets

More...
OpenTargetsi
ENSG00000101442

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA24490

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ACTR5

Domain mapping of disease mutations (DMDM)

More...
DMDMi
110832751

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002478421 – 607Actin-related protein 5Add BLAST607

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki283Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources

Keywords - PTMi

Isopeptide bond, Ubl conjugation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9H9F9

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9H9F9

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9H9F9

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9H9F9

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9H9F9

PeptideAtlas

More...
PeptideAtlasi
Q9H9F9

PRoteomics IDEntifications database

More...
PRIDEi
Q9H9F9

ProteomicsDB human proteome resource

More...
ProteomicsDBi
81319

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9H9F9

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9H9F9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000101442 Expressed in 201 organ(s), highest expression level in epithelium of mammary gland

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9H9F9 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA042676

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the chromatin remodeling INO80 complex; specifically part of a complex module associated with the helicase ATP-binding and the helicase C-terminal domain of INO80.

Interacts with DDB1.

Interacts with ACTR8; the interaction is observed in asynchronous (interphase) cells but not in metaphase-arrested cells indicative for a possible dissociation of the INO80 complex in mitotic cells.

5 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
122993, 48 interactors

ComplexPortal: manually curated resource of macromolecular complexes

More...
ComplexPortali
CPX-846 INO80 chromatin remodeling complex

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
Q9H9F9

Database of interacting proteins

More...
DIPi
DIP-34297N

Protein interaction database and analysis system

More...
IntActi
Q9H9F9, 48 interactors

Molecular INTeraction database

More...
MINTi
Q9H9F9

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000243903

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9H9F9

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili288 – 327Sequence analysisAdd BLAST40
Coiled coili355 – 384Sequence analysisAdd BLAST30

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the actin family. ARP5 subfamily.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0681 Eukaryota
ENOG410XQ7K LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00720000108866

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000171615

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9H9F9

KEGG Orthology (KO)

More...
KOi
K11672

Identification of Orthologs from Complete Genome Data

More...
OMAi
NVGGYHI

Database of Orthologous Groups

More...
OrthoDBi
344271at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9H9F9

TreeFam database of animal gene trees

More...
TreeFami
TF324227

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR004000 Actin
IPR004001 Actin_CS
IPR027664 Arp5

The PANTHER Classification System

More...
PANTHERi
PTHR11937 PTHR11937, 1 hit
PTHR11937:SF16 PTHR11937:SF16, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00022 Actin, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00268 ACTIN, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00432 ACTINS_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9H9F9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAANVFPFRD ARAAPDPVLE AGPVAHGPLP VPLVLDNGSF QVRAGWACPG
60 70 80 90 100
QDPGPEPRLQ FRAVCARGRG GARGASGPQV GNALGSLEPL RWMLRSPFDR
110 120 130 140 150
NVPVNLELQE LLLDYSFQHL GVSSQGCVDH PIVLTEAVCN PLYSRQMMSE
160 170 180 190 200
LLFECYGIPK VAYGIDSLFS FYHNKPKNSM CSGLIISSGY QCTHVLPILE
210 220 230 240 250
GRLDAKNCKR INLGGSQAAG YLQRLLQLKY PGHLAAITLS RMEEILHEHS
260 270 280 290 300
YIAEDYVEEL HKWRCPDYYE NNVHKMQLPF SSKLLGSTLT SEEKQERRQQ
310 320 330 340 350
QLRRLQELNA RRREEKLQLD QERLDRLLYV QELLEDGQMD QFHKALIELN
360 370 380 390 400
MDSPEELQSY IQKLSIAVEQ AKQKILQAEV NLEVDVVDSK PETPDLEQLE
410 420 430 440 450
PSLEDVESMN DFDPLFSEET PGVEKPVTTV QPVFNLAAYH QLFVGTERIR
460 470 480 490 500
APEIIFQPSL IGEEQAGIAE TLQYILDRYP KDIQEMLVQN VFLTGGNTMY
510 520 530 540 550
PGMKARMEKE LLEMRPFRSS FQVQLASNPV LDAWYGARDW ALNHLDDNEV
560 570 580 590 600
WITRKEYEEK GGEYLKEHCA SNIYVPIRLP KQASRSSDAQ ASSKGSAAGG

GGAGEQA
Length:607
Mass (Da):68,297
Last modified:July 25, 2006 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iDA3E50AE37BCC363
GO

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAO65164 differs from that shown. Reason: Frameshift at positions 319, 343 and 347.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti69 – 70RG → AR in AAO65164 (PubMed:12601173).Curated2
Sequence conflicti481K → E in BAB14270 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_027158298R → L1 PublicationCorresponds to variant dbSNP:rs17853829Ensembl.1
Natural variantiVAR_048189461I → L. Corresponds to variant dbSNP:rs35805905Ensembl.1
Natural variantiVAR_027159483I → V1 PublicationCorresponds to variant dbSNP:rs2245231Ensembl.1
Natural variantiVAR_027160580P → L. Corresponds to variant dbSNP:rs3752289Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK022847 mRNA Translation: BAB14270.1
AL133519 Genomic DNA No translation available.
BC001324 mRNA Translation: AAH01324.1
BC006162 mRNA Translation: AAH06162.1
BC038402 mRNA Translation: AAH38402.1
AY211911 mRNA Translation: AAO65164.1 Frameshift.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS13308.1

NCBI Reference Sequences

More...
RefSeqi
NP_079131.3, NM_024855.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000243903; ENSP00000243903; ENSG00000101442

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
79913

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:79913

UCSC genome browser

More...
UCSCi
uc002xjd.3 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK022847 mRNA Translation: BAB14270.1
AL133519 Genomic DNA No translation available.
BC001324 mRNA Translation: AAH01324.1
BC006162 mRNA Translation: AAH06162.1
BC038402 mRNA Translation: AAH38402.1
AY211911 mRNA Translation: AAO65164.1 Frameshift.
CCDSiCCDS13308.1
RefSeqiNP_079131.3, NM_024855.3

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
6HTSelectron microscopy4.80H1-607[»]
SMRiQ9H9F9
ModBaseiSearch...

Protein-protein interaction databases

BioGridi122993, 48 interactors
ComplexPortaliCPX-846 INO80 chromatin remodeling complex
CORUMiQ9H9F9
DIPiDIP-34297N
IntActiQ9H9F9, 48 interactors
MINTiQ9H9F9
STRINGi9606.ENSP00000243903

PTM databases

iPTMnetiQ9H9F9
PhosphoSitePlusiQ9H9F9

Polymorphism and mutation databases

BioMutaiACTR5
DMDMi110832751

Proteomic databases

EPDiQ9H9F9
jPOSTiQ9H9F9
MassIVEiQ9H9F9
MaxQBiQ9H9F9
PaxDbiQ9H9F9
PeptideAtlasiQ9H9F9
PRIDEiQ9H9F9
ProteomicsDBi81319

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000243903; ENSP00000243903; ENSG00000101442
GeneIDi79913
KEGGihsa:79913
UCSCiuc002xjd.3 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
79913
DisGeNETi79913

GeneCards: human genes, protein and diseases

More...
GeneCardsi
ACTR5
HGNCiHGNC:14671 ACTR5
HPAiHPA042676
neXtProtiNX_Q9H9F9
OpenTargetsiENSG00000101442
PharmGKBiPA24490

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG0681 Eukaryota
ENOG410XQ7K LUCA
GeneTreeiENSGT00720000108866
HOGENOMiHOG000171615
InParanoidiQ9H9F9
KOiK11672
OMAiNVGGYHI
OrthoDBi344271at2759
PhylomeDBiQ9H9F9
TreeFamiTF324227

Enzyme and pathway databases

ReactomeiR-HSA-5689603 UCH proteinases
R-HSA-5696394 DNA Damage Recognition in GG-NER
SignaLinkiQ9H9F9

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
79913

Pharos

More...
Pharosi
Q9H9F9

Protein Ontology

More...
PROi
PR:Q9H9F9

Gene expression databases

BgeeiENSG00000101442 Expressed in 201 organ(s), highest expression level in epithelium of mammary gland
GenevisibleiQ9H9F9 HS

Family and domain databases

InterProiView protein in InterPro
IPR004000 Actin
IPR004001 Actin_CS
IPR027664 Arp5
PANTHERiPTHR11937 PTHR11937, 1 hit
PTHR11937:SF16 PTHR11937:SF16, 1 hit
PfamiView protein in Pfam
PF00022 Actin, 2 hits
SMARTiView protein in SMART
SM00268 ACTIN, 1 hit
PROSITEiView protein in PROSITE
PS00432 ACTINS_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiARP5_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9H9F9
Secondary accession number(s): Q86WF7
, Q8IUY5, Q8N724, Q9BRN0, Q9BVB7
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 25, 2006
Last sequence update: July 25, 2006
Last modified: September 18, 2019
This is version 136 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human chromosome 20
    Human chromosome 20: entries, gene names and cross-references to MIM
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  5. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again