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Entry version 149 (16 Oct 2019)
Sequence version 1 (01 Oct 2000)
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Protein

Tuftelin

Gene

TUFT1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Involved in the mineralization and structural organization of enamel.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processBiomineralization

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Tuftelin
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TUFT1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:12422 TUFT1

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
600087 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9NNX1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
7286

Open Targets

More...
OpenTargetsi
ENSG00000143367

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA37084

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9NNX1

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
TUFT1

Domain mapping of disease mutations (DMDM)

More...
DMDMi
22096213

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001831861 – 390TuftelinAdd BLAST390

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9NNX1

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9NNX1

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9NNX1

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9NNX1

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9NNX1

PeptideAtlas

More...
PeptideAtlasi
Q9NNX1

PRoteomics IDEntifications database

More...
PRIDEi
Q9NNX1

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
81861 [Q9NNX1-1]
81862 [Q9NNX1-2]
81863 [Q9NNX1-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9NNX1

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9NNX1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Present in the extracellular enamel and is mainly associated with the crystal component.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000143367 Expressed in 204 organ(s), highest expression level in amniotic fluid

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9NNX1 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9NNX1 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA028112
HPA054301

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with TFIP11.

By similarity

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
113137, 54 interactors

Protein interaction database and analysis system

More...
IntActi
Q9NNX1, 16 interactors

Molecular INTeraction database

More...
MINTi
Q9NNX1

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000357842

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9NNX1

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili88 – 126Sequence analysisAdd BLAST39
Coiled coili162 – 351Sequence analysisAdd BLAST190

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the tuftelin family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IGQQ Eukaryota
ENOG4111JYX LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000183065

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9NNX1

Identification of Orthologs from Complete Genome Data

More...
OMAi
HSNFSTQ

Database of Orthologous Groups

More...
OrthoDBi
1003198at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9NNX1

TreeFam database of animal gene trees

More...
TreeFami
TF331627

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR024846 Tuftelin

The PANTHER Classification System

More...
PANTHERi
PTHR23171:SF4 PTHR23171:SF4, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9NNX1-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MNGTRNWCTL VDVHPEDQAA GSVDILRLTL QGELTGDELE HIAQKAGRKT
60 70 80 90 100
YAMVSSHSAG HSLASELVES HDGHEEIIKV YLKGRSGDKM IHEKNINQLK
110 120 130 140 150
SEVQYIQEAR NCLQKLREDI SSKLDRNLGD SLHRQEIQVV LEKPNGFSQS
160 170 180 190 200
PTALYSSPPE VDTCINEDVE SLRKTVQDLL AKLQEAKRQH QSDCVAFEVT
210 220 230 240 250
LSRYQREAEQ SNVALQREED RVEQKEAEVG ELQRRLLGME TEHQALLAKV
260 270 280 290 300
REGEVALEEL RSNNADCQAE REKAATLEKE VAGLREKIHH LDDMLKSQQR
310 320 330 340 350
KVRQMIEQLQ NSKAVIQSKD ATIQELKEKI AYLEAENLEM HDRMEHLIEK
360 370 380 390
QISHGNFSTQ ARAKTENPGS IRISKPPSPK PMPVIRVVET
Length:390
Mass (Da):44,264
Last modified:October 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i332AF3C06665E8D0
GO
Isoform 2 (identifier: Q9NNX1-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     21-45: Missing.

Show »
Length:365
Mass (Da):41,546
Checksum:i3A12985BF4AC3033
GO
Isoform 3 (identifier: Q9NNX1-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     21-79: Missing.

Show »
Length:331
Mass (Da):37,929
Checksum:i9F858A5CE5FBB30A
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A6PVU8A6PVU8_HUMAN
Tuftelin
TUFT1
335Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q6UWW7Q6UWW7_HUMAN
TUFT1
TUFT1 UNQ865
199Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAB15615 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti244Q → R in BAB15615 (PubMed:14702039).Curated1
Sequence conflicti329K → T in BAB15615 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_05242418Q → R. Corresponds to variant dbSNP:rs3828054Ensembl.1
Natural variantiVAR_034574296K → R. Corresponds to variant dbSNP:rs16833395Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_00668621 – 79Missing in isoform 3. 1 PublicationAdd BLAST59
Alternative sequenceiVSP_00668521 – 45Missing in isoform 2. 3 PublicationsAdd BLAST25

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF254860
, AF254850, AF254851, AF254852, AF254854, AF254855, AF254856, AF254857, AF254858, AF254859 Genomic DNA Translation: AAF78914.1
AF254260 mRNA Translation: AAF78913.1
AL136917 mRNA Translation: CAB66851.1
AK026989 mRNA Translation: BAB15615.1 Different initiation.
AK075001 mRNA Translation: BAC11346.1
AK315414 mRNA Translation: BAG37804.1
AL365436 Genomic DNA No translation available.
CH471121 Genomic DNA Translation: EAW53429.1
CH471121 Genomic DNA Translation: EAW53430.1
CH471121 Genomic DNA Translation: EAW53431.1
CH471121 Genomic DNA Translation: EAW53433.1
BC002933 mRNA Translation: AAH02933.1
BC008301 mRNA Translation: AAH08301.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS1000.1 [Q9NNX1-1]
CCDS44223.1 [Q9NNX1-2]

NCBI Reference Sequences

More...
RefSeqi
NP_001119809.1, NM_001126337.1 [Q9NNX1-2]
NP_001288246.1, NM_001301317.1
NP_064512.1, NM_020127.2 [Q9NNX1-1]
XP_011508263.1, XM_011509961.2 [Q9NNX1-3]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000368848; ENSP00000357841; ENSG00000143367 [Q9NNX1-2]
ENST00000368849; ENSP00000357842; ENSG00000143367 [Q9NNX1-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
7286

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:7286

UCSC genome browser

More...
UCSCi
uc001eyl.3 human [Q9NNX1-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF254860
, AF254850, AF254851, AF254852, AF254854, AF254855, AF254856, AF254857, AF254858, AF254859 Genomic DNA Translation: AAF78914.1
AF254260 mRNA Translation: AAF78913.1
AL136917 mRNA Translation: CAB66851.1
AK026989 mRNA Translation: BAB15615.1 Different initiation.
AK075001 mRNA Translation: BAC11346.1
AK315414 mRNA Translation: BAG37804.1
AL365436 Genomic DNA No translation available.
CH471121 Genomic DNA Translation: EAW53429.1
CH471121 Genomic DNA Translation: EAW53430.1
CH471121 Genomic DNA Translation: EAW53431.1
CH471121 Genomic DNA Translation: EAW53433.1
BC002933 mRNA Translation: AAH02933.1
BC008301 mRNA Translation: AAH08301.1
CCDSiCCDS1000.1 [Q9NNX1-1]
CCDS44223.1 [Q9NNX1-2]
RefSeqiNP_001119809.1, NM_001126337.1 [Q9NNX1-2]
NP_001288246.1, NM_001301317.1
NP_064512.1, NM_020127.2 [Q9NNX1-1]
XP_011508263.1, XM_011509961.2 [Q9NNX1-3]

3D structure databases

SMRiQ9NNX1
ModBaseiSearch...

Protein-protein interaction databases

BioGridi113137, 54 interactors
IntActiQ9NNX1, 16 interactors
MINTiQ9NNX1
STRINGi9606.ENSP00000357842

PTM databases

iPTMnetiQ9NNX1
PhosphoSitePlusiQ9NNX1

Polymorphism and mutation databases

BioMutaiTUFT1
DMDMi22096213

Proteomic databases

EPDiQ9NNX1
jPOSTiQ9NNX1
MassIVEiQ9NNX1
MaxQBiQ9NNX1
PaxDbiQ9NNX1
PeptideAtlasiQ9NNX1
PRIDEiQ9NNX1
ProteomicsDBi81861 [Q9NNX1-1]
81862 [Q9NNX1-2]
81863 [Q9NNX1-3]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
7286

Genome annotation databases

EnsembliENST00000368848; ENSP00000357841; ENSG00000143367 [Q9NNX1-2]
ENST00000368849; ENSP00000357842; ENSG00000143367 [Q9NNX1-1]
GeneIDi7286
KEGGihsa:7286
UCSCiuc001eyl.3 human [Q9NNX1-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
7286
DisGeNETi7286

GeneCards: human genes, protein and diseases

More...
GeneCardsi
TUFT1
HGNCiHGNC:12422 TUFT1
HPAiHPA028112
HPA054301
MIMi600087 gene
neXtProtiNX_Q9NNX1
OpenTargetsiENSG00000143367
PharmGKBiPA37084

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IGQQ Eukaryota
ENOG4111JYX LUCA
GeneTreeiENSGT00950000183065
InParanoidiQ9NNX1
OMAiHSNFSTQ
OrthoDBi1003198at2759
PhylomeDBiQ9NNX1
TreeFamiTF331627

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
TUFT1 human

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
Tuftelin

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
7286
PharosiQ9NNX1

Protein Ontology

More...
PROi
PR:Q9NNX1

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000143367 Expressed in 204 organ(s), highest expression level in amniotic fluid
ExpressionAtlasiQ9NNX1 baseline and differential
GenevisibleiQ9NNX1 HS

Family and domain databases

InterProiView protein in InterPro
IPR024846 Tuftelin
PANTHERiPTHR23171:SF4 PTHR23171:SF4, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTUFT1_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9NNX1
Secondary accession number(s): B2RD57
, D3DV21, D3DV22, Q5T384, Q5T385, Q9BU28, Q9H5L1
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 2, 2002
Last sequence update: October 1, 2000
Last modified: October 16, 2019
This is version 149 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  4. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  5. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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