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Entry version 167 (16 Oct 2019)
Sequence version 3 (30 Nov 2010)
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Protein

Ubiquinone biosynthesis O-methyltransferase, mitochondrial

Gene

COQ3

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.UniRule annotation

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: ubiquinone biosynthesis

This protein is involved in the pathway ubiquinone biosynthesis, which is part of Cofactor biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway ubiquinone biosynthesis and in Cofactor biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei124S-adenosyl-L-methionineUniRule annotation1
Binding sitei154S-adenosyl-L-methionine; via carbonyl oxygenUniRule annotation1
Binding sitei175S-adenosyl-L-methionineUniRule annotation1
Binding sitei222S-adenosyl-L-methionine; via carbonyl oxygenUniRule annotation1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionMethyltransferase, Transferase
Biological processUbiquinone biosynthesis
LigandS-adenosyl-L-methionine

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
MetaCyc:HS05632-MONOMER

BRENDA Comprehensive Enzyme Information System

More...
BRENDAi
2.1.1.114 2681
2.1.1.222 2681
2.1.1.64 2681

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-2142789 Ubiquinol biosynthesis

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...
UniPathwayi
UPA00232

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Ubiquinone biosynthesis O-methyltransferase, mitochondrialUniRule annotation
Alternative name(s):
3-demethylubiquinol 3-O-methyltransferaseUniRule annotation (EC:2.1.1.64UniRule annotation)
Polyprenyldihydroxybenzoate methyltransferaseUniRule annotation (EC:2.1.1.114UniRule annotation)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:COQ3UniRule annotation
ORF Names:UG0215E05
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:18175 COQ3

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
605196 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9NZJ6

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000132423

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134934287

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9NZJ6

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
COQ3

Domain mapping of disease mutations (DMDM)

More...
DMDMi
313104241

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a transit peptide.<p><a href='/help/transit' target='_top'>More...</a></p>Transit peptidei1 – 85MitochondrionUniRule annotationAdd BLAST85
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000003592686 – 369Ubiquinone biosynthesis O-methyltransferase, mitochondrialAdd BLAST284

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei143N6-acetyllysineBy similarity1
Modified residuei149N6-acetyllysineBy similarity1
Modified residuei196N6-acetyllysineBy similarity1

Keywords - PTMi

Acetylation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9NZJ6

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9NZJ6

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9NZJ6

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9NZJ6

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9NZJ6

PeptideAtlas

More...
PeptideAtlasi
Q9NZJ6

PRoteomics IDEntifications database

More...
PRIDEi
Q9NZJ6

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
83417

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9NZJ6

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9NZJ6

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000132423 Expressed in 207 organ(s), highest expression level in biceps brachii

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9NZJ6 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9NZJ6 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA031273
HPA031274

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.

UniRule annotation

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
119731, 16 interactors

ComplexPortal: manually curated resource of macromolecular complexes

More...
ComplexPortali
CPX-3642 CoQ biosynthetic complex

Protein interaction database and analysis system

More...
IntActi
Q9NZJ6, 16 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000254759

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9NZJ6

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.UniRule annotation

Keywords - Domaini

Transit peptide

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1270 Eukaryota
COG2227 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000007284

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9NZJ6

KEGG Orthology (KO)

More...
KOi
K00591

Identification of Orthologs from Complete Genome Data

More...
OMAi
IVPRGTH

Database of Orthologous Groups

More...
OrthoDBi
1542938at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9NZJ6

TreeFam database of animal gene trees

More...
TreeFami
TF314553

Family and domain databases

HAMAP database of protein families

More...
HAMAPi
MF_00472 UbiG, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR029063 SAM-dependent_MTases
IPR010233 UbiG_MeTrfase

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF53335 SSF53335, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR01983 UbiG, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q9NZJ6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MWSGRKLGSS GGWFLRVLGP GGCNTKAARP LISSAVYVKN QLSGTLQIKP
60 70 80 90 100
GVFNEYRTIW FKSYRTIFSC LNRIKSFRYP WARLYSTSQT TVDSGEVKTF
110 120 130 140 150
LALAHKWWDE QGVYAPLHSM NDLRVPFIRD NLLKTIPNHQ PGKPLLGMKI
160 170 180 190 200
LDVGCGGGLL TEPLGRLGAS VIGIDPVDEN IKTAQCHKSF DPVLDKRIEY
210 220 230 240 250
RVCSLEEIVE ETAETFDAVV ASEVVEHVID LETFLQCCCQ VLKPGGSLFI
260 270 280 290 300
TTINKTQLSY ALGIVFSEQI ASIVPKGTHT WEKFVSPETL ESILESNGLS
310 320 330 340 350
VQTVVGMLYN PFSGYWHWSE NTSLNYAAYA VKSRVQEHPA SAEFVLKGET
360
EELQANACTN PAVHEKLKK
Length:369
Mass (Da):41,054
Last modified:November 30, 2010 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB257A099D6C06A2D
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F6WGP0F6WGP0_HUMAN
Ubiquinone biosynthesis O-methyltra...
COQ3
141Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAF66826 differs from that shown. Reason: Frameshift.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti21G → V in CAB66660 (PubMed:11230166).Curated1
Sequence conflicti180N → D in CAB66660 (PubMed:11230166).Curated1
Sequence conflicti287 – 289PET → LEP in AAN76515 (Ref. 1) Curated3
Sequence conflicti321N → D in AAN76515 (Ref. 1) Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_061925134K → E2 PublicationsCorresponds to variant dbSNP:rs11548336Ensembl.1
Natural variantiVAR_020789272S → G4 PublicationsCorresponds to variant dbSNP:rs6925344Ensembl.1
Natural variantiVAR_020790329Y → H5 PublicationsCorresponds to variant dbSNP:rs4144164Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF351615 mRNA Translation: AAN76515.1
AL136726 mRNA Translation: CAB66660.1
AK056955 mRNA Translation: BAG51832.1
AL513550 Genomic DNA No translation available.
BC015634 mRNA Translation: AAH15634.2
BC063463 mRNA Translation: AAH63463.1
AF193016 mRNA Translation: AAF66826.1 Frameshift.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS5042.1

NCBI Reference Sequences

More...
RefSeqi
NP_059117.3, NM_017421.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000254759; ENSP00000254759; ENSG00000132423

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
51805

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:51805

UCSC genome browser

More...
UCSCi
uc003ppk.4 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF351615 mRNA Translation: AAN76515.1
AL136726 mRNA Translation: CAB66660.1
AK056955 mRNA Translation: BAG51832.1
AL513550 Genomic DNA No translation available.
BC015634 mRNA Translation: AAH15634.2
BC063463 mRNA Translation: AAH63463.1
AF193016 mRNA Translation: AAF66826.1 Frameshift.
CCDSiCCDS5042.1
RefSeqiNP_059117.3, NM_017421.3

3D structure databases

SMRiQ9NZJ6
ModBaseiSearch...

Protein-protein interaction databases

BioGridi119731, 16 interactors
ComplexPortaliCPX-3642 CoQ biosynthetic complex
IntActiQ9NZJ6, 16 interactors
STRINGi9606.ENSP00000254759

PTM databases

iPTMnetiQ9NZJ6
PhosphoSitePlusiQ9NZJ6

Polymorphism and mutation databases

BioMutaiCOQ3
DMDMi313104241

Proteomic databases

EPDiQ9NZJ6
jPOSTiQ9NZJ6
MassIVEiQ9NZJ6
MaxQBiQ9NZJ6
PaxDbiQ9NZJ6
PeptideAtlasiQ9NZJ6
PRIDEiQ9NZJ6
ProteomicsDBi83417

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
51805

Genome annotation databases

EnsembliENST00000254759; ENSP00000254759; ENSG00000132423
GeneIDi51805
KEGGihsa:51805
UCSCiuc003ppk.4 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
51805

GeneCards: human genes, protein and diseases

More...
GeneCardsi
COQ3
HGNCiHGNC:18175 COQ3
HPAiHPA031273
HPA031274
MIMi605196 gene
neXtProtiNX_Q9NZJ6
OpenTargetsiENSG00000132423
PharmGKBiPA134934287

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1270 Eukaryota
COG2227 LUCA
GeneTreeiENSGT00390000007284
InParanoidiQ9NZJ6
KOiK00591
OMAiIVPRGTH
OrthoDBi1542938at2759
PhylomeDBiQ9NZJ6
TreeFamiTF314553

Enzyme and pathway databases

UniPathwayiUPA00232
BioCyciMetaCyc:HS05632-MONOMER
BRENDAi2.1.1.114 2681
2.1.1.222 2681
2.1.1.64 2681
ReactomeiR-HSA-2142789 Ubiquinol biosynthesis

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
COQ3 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
51805
PharosiQ9NZJ6

Protein Ontology

More...
PROi
PR:Q9NZJ6

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000132423 Expressed in 207 organ(s), highest expression level in biceps brachii
ExpressionAtlasiQ9NZJ6 baseline and differential
GenevisibleiQ9NZJ6 HS

Family and domain databases

HAMAPiMF_00472 UbiG, 1 hit
InterProiView protein in InterPro
IPR029063 SAM-dependent_MTases
IPR010233 UbiG_MeTrfase
SUPFAMiSSF53335 SSF53335, 1 hit
TIGRFAMsiTIGR01983 UbiG, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCOQ3_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9NZJ6
Secondary accession number(s): B3KPX0
, Q5T061, Q6P4F0, Q8IXG6, Q96BG1, Q9H0N1
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 2, 2001
Last sequence update: November 30, 2010
Last modified: October 16, 2019
This is version 167 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 6
    Human chromosome 6: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. SIMILARITY comments
    Index of protein domains and families
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  5. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  6. PATHWAY comments
    Index of metabolic and biosynthesis pathways
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