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Entry version 141 (13 Nov 2019)
Sequence version 1 (01 May 2000)
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Protein

Acyl-coenzyme A thioesterase 3

Gene

Acot3

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH (PubMed:16940157). Acyl-CoA thioesterase 3/ACOT3 is mainly active on long-chain acyl-CoAs (PubMed:15007068, PubMed:16940157). May have a function in termination of beta-oxidation of fatty acids (PubMed:16940157).1 Publication2 Publications

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the ‘Function’ section describes biophysical and chemical properties, such as maximal absorption, kinetic parameters, pH dependence, redox potentials and temperature dependence.<p><a href='/help/biophysicochemical_properties' target='_top'>More...</a></p>Kineticsi

  1. KM=10.9 µM for hexanoyl-coA1 Publication
  2. KM=46.2 µM for octanoyl-coA1 Publication
  3. KM=7.7 µM for decanoyl-coA1 Publication
  4. KM=7.6 µM for dodecanoyl-coA1 Publication
  5. KM=3.8 µM for tetradecanoyl-coA1 Publication
  6. KM=4.0 µM for hexadecanoyl-coA1 Publication
  7. KM=2.8 µM for (9Z)-hexadecenoyl-coA1 Publication
  8. KM=4.2 µM for octadecanoyl-coA1 Publication
  9. KM=4.6 µM for (9Z)-octadecenoyl-coA1 Publication
  10. KM=2.6 µM for (9Z,12Z)-octadecadienoyl-coA1 Publication
  11. KM=2.2 µM for eicosanoyl-coA1 Publication
  12. KM=7.2 µM for (5Z,8Z,11Z,14Z)-eicosatetraenoyl-coA1 Publication
  13. KM=2.3 µM for docosanoyl-coA1 Publication
  14. KM=6.3 µM for tetracosanoyl-coA1 Publication
  15. KM=4.5 µM for hexacosanoyl-coA1 Publication
  1. Vmax=0.02 µmol/min/mg enzyme with hexanoyl-coA as substrate1 Publication
  2. Vmax=0.23 µmol/min/mg enzyme with octanoyl-coA as substrate1 Publication
  3. Vmax=0.87 µmol/min/mg enzyme with decanoyl-coA as substrate1 Publication
  4. Vmax=1.40 µmol/min/mg enzyme with dodecanoyl-coA as substrate1 Publication
  5. Vmax=1.60 µmol/min/mg enzyme with tetradecanoyl-coA as substrate1 Publication
  6. Vmax=1.85 µmol/min/mg enzyme with hexadecanoyl-coA as substrate1 Publication
  7. Vmax=0.93 µmol/min/mg enzyme with (9Z)-hexadecenoyl-coA as substrate1 Publication
  8. Vmax=1.43 µmol/min/mg enzyme with octadecanoyl-coA as substrate1 Publication
  9. Vmax=0.85 µmol/min/mg enzyme with (9Z)-octadecenoyl-coA as substrate1 Publication
  10. Vmax=0.63 µmol/min/mg enzyme with (9Z,12Z)-octadecadienoyl-coA as substrate1 Publication
  11. Vmax=0.71 µmol/min/mg enzyme with eicosanoyl-coA as substrate1 Publication
  12. Vmax=0.70 µmol/min/mg enzyme with (5Z,8Z,11Z,14Z)-eicosatetraenoyl-coA as substrate1 Publication
  13. Vmax=0.37 µmol/min/mg enzyme with docosanoyl-coA as substrate1 Publication
  14. Vmax=0.20 µmol/min/mg enzyme with tetracosanoyl-coA as substrate1 Publication
  15. Vmax=0.22 µmol/min/mg enzyme with hexacosanoyl-coA as substrate1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: fatty acid metabolism

This protein is involved in the pathway fatty acid metabolism, which is part of Lipid metabolism.2 Publications
View all proteins of this organism that are known to be involved in the pathway fatty acid metabolism and in Lipid metabolism.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei243Charge relay systemBy similarity1
Active sitei337Charge relay systemBy similarity1
Active sitei371Charge relay systemBy similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolase, Serine esterase
Biological processFatty acid metabolism, Lipid metabolism

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-77289 Mitochondrial Fatty Acid Beta-Oxidation
R-MMU-9033241 Peroxisomal protein import

SABIO-RK: Biochemical Reaction Kinetics Database

More...
SABIO-RKi
Q9QYR7

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...
UniPathwayi
UPA00199

Protein family/group databases

ESTHER database of the Alpha/Beta-hydrolase fold superfamily of proteins

More...
ESTHERi
mouse-acot3 Acyl-CoA_Thioesterase

MEROPS protease database

More...
MEROPSi
S09.A51

Chemistry databases

SwissLipids knowledge resource for lipid biology

More...
SwissLipidsi
SLP:000000530

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Acyl-coenzyme A thioesterase 3 (EC:3.1.2.21 Publication)
Short name:
Acyl-CoA thioesterase 3
Alternative name(s):
PTE-Ia
Peroxisomal acyl-coenzyme A thioester hydrolase 2a
Peroxisomal long-chain acyl-CoA thioesterase 2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Acot3
Synonyms:Pte1a, Pte2, Pte2a
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 12

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:2159619 Acot3

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Peroxisome

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002021481 – 432Acyl-coenzyme A thioesterase 3Add BLAST432

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9QYR7

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9QYR7

PRoteomics IDEntifications database

More...
PRIDEi
Q9QYR7

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9QYR7

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9QYR7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Widely expressed. Highly expressed in the kidney, expressed at low level in the liver. Isoform 2 is expressed in the kidney, but not in the liver. Isoform 1 is liver-specific (PubMed:10567408). Highly expressed in kidney (at protein level) (PubMed:15007068).2 Publications

<p>This subsection of the ‘Expression’ section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

In the liver and kidney, by peroxisome proliferator (such as Clofibrate) treatment, via the peroxisome proliferator-activated receptors (PPARs) or fasting for 24 hours.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000021228 Expressed in 77 organ(s), highest expression level in liver

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9QYR7 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9QYR7 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
Q9QYR7, 4 interactors

Molecular INTeraction database

More...
MINTi
Q9QYR7

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000021653

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9QYR7

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi430 – 432Microbody targeting signalSequence analysis3

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the C/M/P thioester hydrolase family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410II3X Eukaryota
COG1073 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000182784

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000116219

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9QYR7

KEGG Orthology (KO)

More...
KOi
K01068

Database of Orthologous Groups

More...
OrthoDBi
1260385at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9QYR7

TreeFam database of animal gene trees

More...
TreeFami
TF314911

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.2240, 1 hit
3.40.50.1820, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR029058 AB_hydrolase
IPR016662 Acyl-CoA_thioEstase_long-chain
IPR014940 BAAT_C
IPR006862 Thio_Ohase/aa_AcTrfase
IPR042490 Thio_Ohase/BAAT_N

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF08840 BAAT_C, 1 hit
PF04775 Bile_Hydr_Trans, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF016521 Acyl-CoA_hydro, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF53474 SSF53474, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9QYR7-1) [UniParc]FASTAAdd to basket
Also known as: PTE-Ia 5':1

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MHAFTTQNPN RMAPTVILEP AGGCLCDQPV HIAVRGLAPE QPVTLRSVLR
60 70 80 90 100
DEKGALFRAH ARYRADSHGE LDLARTPALG GSFSGLEPMG LLWAMEPDRP
110 120 130 140 150
FWRLIKRDVQ TPFVVELEVL DGHEPDGGQR LARAVHERHF MAPGVRRVPV
160 170 180 190 200
REGRVRATLF LPPGTGPFPG IIDLFGIGSG LLEYRASLLA GKGFAVMALA
210 220 230 240 250
YNNYEDLPKD MDIIHLEYFE EAVTYLLSHP QVTGSGVGVL GISKGGELGF
260 270 280 290 300
AMASFLKNIT AAVIINGSIS NIGGNLQYKD ETVPSVGINT KRVKRTKDGL
310 320 330 340 350
KDIVDLLNNP LEGPDQKSLI PVERSDTAFL FLVGQDDHNW KSEFYAREAS
360 370 380 390 400
KRLQAHGKEK PQIICYPETG HHIEPPYFPL CKASLNSLVG GPVIWGGEPR
410 420 430
AHAMAQVDAW QQLQTFFHNH LDGKKKTIPA KL
Length:432
Mass (Da):47,490
Last modified:May 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iBF5888C59C015359
GO
Isoform 2 (identifier: Q9QYR7-2) [UniParc]FASTAAdd to basket
Also known as: PTE-Ia 5':2

The sequence of this isoform differs from the canonical sequence as follows:
     1-11: Missing.

Show »
Length:421
Mass (Da):46,191
Checksum:i4146258877CBDB88
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1Y7VMZ4A0A1Y7VMZ4_MOUSE
Acyl-coenzyme A thioesterase 3
Acot3
282Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0109941 – 11Missing in isoform 2. 1 PublicationAdd BLAST11

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF180804, AF180802, AF180803 Genomic DNA Translation: AAF13873.1
AY563098 mRNA Translation: AAS75456.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS26036.1 [Q9QYR7-1]
CCDS83985.1 [Q9QYR7-2]

NCBI Reference Sequences

More...
RefSeqi
NP_001333630.1, NM_001346701.1 [Q9QYR7-2]
NP_599007.1, NM_134246.3 [Q9QYR7-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000021653; ENSMUSP00000021653; ENSMUSG00000021228 [Q9QYR7-1]
ENSMUST00000120927; ENSMUSP00000112678; ENSMUSG00000021228 [Q9QYR7-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
171281

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:171281

UCSC genome browser

More...
UCSCi
uc007oef.1 mouse [Q9QYR7-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF180804, AF180802, AF180803 Genomic DNA Translation: AAF13873.1
AY563098 mRNA Translation: AAS75456.1
CCDSiCCDS26036.1 [Q9QYR7-1]
CCDS83985.1 [Q9QYR7-2]
RefSeqiNP_001333630.1, NM_001346701.1 [Q9QYR7-2]
NP_599007.1, NM_134246.3 [Q9QYR7-1]

3D structure databases

SMRiQ9QYR7
ModBaseiSearch...

Protein-protein interaction databases

IntActiQ9QYR7, 4 interactors
MINTiQ9QYR7
STRINGi10090.ENSMUSP00000021653

Chemistry databases

SwissLipidsiSLP:000000530

Protein family/group databases

ESTHERimouse-acot3 Acyl-CoA_Thioesterase
MEROPSiS09.A51

PTM databases

iPTMnetiQ9QYR7
PhosphoSitePlusiQ9QYR7

Proteomic databases

jPOSTiQ9QYR7
PaxDbiQ9QYR7
PRIDEiQ9QYR7

Genome annotation databases

EnsembliENSMUST00000021653; ENSMUSP00000021653; ENSMUSG00000021228 [Q9QYR7-1]
ENSMUST00000120927; ENSMUSP00000112678; ENSMUSG00000021228 [Q9QYR7-2]
GeneIDi171281
KEGGimmu:171281
UCSCiuc007oef.1 mouse [Q9QYR7-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
171281
MGIiMGI:2159619 Acot3

Phylogenomic databases

eggNOGiENOG410II3X Eukaryota
COG1073 LUCA
GeneTreeiENSGT00950000182784
HOGENOMiHOG000116219
InParanoidiQ9QYR7
KOiK01068
OrthoDBi1260385at2759
PhylomeDBiQ9QYR7
TreeFamiTF314911

Enzyme and pathway databases

UniPathwayiUPA00199
ReactomeiR-MMU-77289 Mitochondrial Fatty Acid Beta-Oxidation
R-MMU-9033241 Peroxisomal protein import
SABIO-RKiQ9QYR7

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q9QYR7

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000021228 Expressed in 77 organ(s), highest expression level in liver
ExpressionAtlasiQ9QYR7 baseline and differential
GenevisibleiQ9QYR7 MM

Family and domain databases

Gene3Di2.60.40.2240, 1 hit
3.40.50.1820, 1 hit
InterProiView protein in InterPro
IPR029058 AB_hydrolase
IPR016662 Acyl-CoA_thioEstase_long-chain
IPR014940 BAAT_C
IPR006862 Thio_Ohase/aa_AcTrfase
IPR042490 Thio_Ohase/BAAT_N
PfamiView protein in Pfam
PF08840 BAAT_C, 1 hit
PF04775 Bile_Hydr_Trans, 1 hit
PIRSFiPIRSF016521 Acyl-CoA_hydro, 1 hit
SUPFAMiSSF53474 SSF53474, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiACOT3_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9QYR7
Secondary accession number(s): Q6Q2Z7
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 8, 2000
Last sequence update: May 1, 2000
Last modified: November 13, 2019
This is version 141 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  3. PATHWAY comments
    Index of metabolic and biosynthesis pathways
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