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Entry version 157 (16 Oct 2019)
Sequence version 1 (01 May 2000)
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Protein

Coatomer subunit gamma-2

Gene

COPG2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors (By similarity).By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processER-Golgi transport, Protein transport, Transport

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-6807878 COPI-mediated anterograde transport
R-HSA-6811434 COPI-dependent Golgi-to-ER retrograde traffic

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Coatomer subunit gamma-2
Alternative name(s):
Gamma-2-coat protein
Short name:
Gamma-2-COP
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:COPG2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:2237 COPG2

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
604355 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9UBF2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Cytoplasmic vesicle, Golgi apparatus, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
26958

Open Targets

More...
OpenTargetsi
ENSG00000158623

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA26753

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9UBF2

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
COPG2

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001938621 – 871Coatomer subunit gamma-2Add BLAST871

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei594PhosphothreonineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9UBF2

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9UBF2

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9UBF2

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9UBF2

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9UBF2

PeptideAtlas

More...
PeptideAtlasi
Q9UBF2

PRoteomics IDEntifications database

More...
PRIDEi
Q9UBF2

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
83955 [Q9UBF2-1]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9UBF2

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9UBF2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000158623 Expressed in 161 organ(s), highest expression level in right adrenal gland

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9UBF2 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9UBF2 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA045712

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Oligomeric complex. Binds to CDC42.

Interacts with JAGN1.

1 Publication

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
117926, 48 interactors

Protein interaction database and analysis system

More...
IntActi
Q9UBF2, 23 interactors

Molecular INTeraction database

More...
MINTi
Q9UBF2

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000402346

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati64 – 101HEAT 1Add BLAST38
Repeati283 – 320HEAT 2Add BLAST38
Repeati321 – 355HEAT 3Add BLAST35
Repeati356 – 392HEAT 4Add BLAST37
Repeati395 – 430HEAT 5Add BLAST36
Repeati467 – 504HEAT 6Add BLAST38

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the COPG family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1078 Eukaryota
COG5240 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000016313

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9UBF2

KEGG Orthology (KO)

More...
KOi
K17267

Identification of Orthologs from Complete Genome Data

More...
OMAi
RTIVECM

Database of Orthologous Groups

More...
OrthoDBi
255234at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9UBF2

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.10.10, 1 hit
2.60.40.1480, 1 hit
3.30.310.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR002553 Clathrin/coatomer_adapt-like_N
IPR013041 Clathrin_app_Ig-like_sf
IPR009028 Coatomer/calthrin_app_sub_C
IPR032154 Coatomer_g_Cpla
IPR017106 Coatomer_gsu
IPR013040 Coatomer_gsu_app_Ig-like_dom
IPR037067 Coatomer_gsu_app_sf
IPR012295 TBP_dom_sf

The PANTHER Classification System

More...
PANTHERi
PTHR10261 PTHR10261, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01602 Adaptin_N, 1 hit
PF16381 Coatomer_g_Cpla, 1 hit
PF08752 COP-gamma_platf, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF037093 Coatomer_gamma_subunit, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48371 SSF48371, 1 hit
SSF49348 SSF49348, 1 hit
SSF55711 SSF55711, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q9UBF2-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MIKKFDKKDE ESGSGSNPFQ HLEKSAVLQE ARIFNETPIN PRRCLHILTK
60 70 80 90 100
ILYLLNQGEH FGTTEATEAF FAMTRLFQSN DQTLRRMCYL TIKEMATISE
110 120 130 140 150
DVIIVTSSLT KDMTGKEDVY RGPAIRALCR ITDGTMLQAI ERYMKQAIVD
160 170 180 190 200
KVSSVSSSAL VSSLHMMKIS YDVVKRWINE AQEAASSDNI MVQYHALGVL
210 220 230 240 250
YHLRKNDRLA VSKMLNKFTK SGLKSQFAYC MLIRIASRLL KETEDGHESP
260 270 280 290 300
LFDFIESCLR NKHEMVIYEA ASAIIHLPNC TARELAPAVS VLQLFCSSPK
310 320 330 340 350
PALRYAAVRT LNKVAMKHPS AVTACNLDLE NLITDSNRSI ATLAITTLLK
360 370 380 390 400
TGSESSVDRL MKQISSFVSE ISDEFKVVVV QAISALCQKY PRKHSVMMTF
410 420 430 440 450
LSNMLRDDGG FEYKRAIVDC IISIVEENPE SKEAGLAHLC EFIEDCEHTV
460 470 480 490 500
LATKILHLLG KEGPRTPVPS KYIRFIFNRV VLENEAVRAA AVSALAKFGA
510 520 530 540 550
QNESLLPSIL VLLQRCMMDT DDEVRDRATF YLNVLQQRQM ALNATYIFNG
560 570 580 590 600
LTVSVPGMEK ALHQYTLEPS EKPFDMKSIP LAMAPVFEQK AEITLVATKP
610 620 630 640 650
EKLAPSRQDI FQEQLAAIPE FLNIGPLFKS SEPVQLTEAE TEYFVRCIKH
660 670 680 690 700
MFTNHIVFQF DCTNTLNDQL LEKVTVQMEP SDSYEVLSCI PAPSLPYNQP
710 720 730 740 750
GICYTLVRLP DDDPTAVAGS FSCTMKFTVR DCDPNTGVPD EDGYDDEYVL
760 770 780 790 800
EDLEVTVSDH IQKVLKPNFA AAWEEVGDTF EKEETFALSS TKTLEEAVNN
810 820 830 840 850
IITFLGMQPC ERSDKVPENK NSHSLYLAGI FRGGYDLLVR SRLALADGVT
860 870
MQVTVRSKER TPVDVILASV G
Length:871
Mass (Da):97,622
Last modified:May 1, 2000 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD361A0E74069CBEB
GO
Isoform 2 (identifier: Q9UBF2-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     717-726: VAGSFSCTMK → GTNPQKGGDT
     727-871: Missing.

Note: No experimental confirmation available.
Show »
Length:726
Mass (Da):81,483
Checksum:i808D4BC052AE37D6
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_060181547I → L. Corresponds to variant dbSNP:rs10128Ensembl.1
Natural variantiVAR_060182626P → L. Corresponds to variant dbSNP:rs17333054Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_055534717 – 726VAGSFSCTMK → GTNPQKGGDT in isoform 2. 1 Publication10
Alternative sequenceiVSP_055535727 – 871Missing in isoform 2. 1 PublicationAdd BLAST145

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF207598 mRNA Translation: AAF19433.1
AF157833 mRNA Translation: AAF14271.1
AB047847 mRNA Translation: BAB17658.1
AK291409 mRNA Translation: BAF84098.1
AC090520 Genomic DNA No translation available.
AC009274 Genomic DNA No translation available.
AC007938 Genomic DNA No translation available.
CH236950 Genomic DNA Translation: EAL24085.1
CH471070 Genomic DNA Translation: EAW83769.1
BC017443 mRNA Translation: AAH17443.2
BC110796 mRNA Translation: AAI10797.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS75662.1 [Q9UBF2-1]
CCDS78275.1 [Q9UBF2-2]

NCBI Reference Sequences

More...
RefSeqi
NP_001276962.1, NM_001290033.1 [Q9UBF2-2]
NP_036265.3, NM_012133.5 [Q9UBF2-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000330992; ENSP00000331218; ENSG00000158623 [Q9UBF2-2]
ENST00000425248; ENSP00000402346; ENSG00000158623 [Q9UBF2-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
26958

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:26958

UCSC genome browser

More...
UCSCi
uc033ahl.2 human [Q9UBF2-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF207598 mRNA Translation: AAF19433.1
AF157833 mRNA Translation: AAF14271.1
AB047847 mRNA Translation: BAB17658.1
AK291409 mRNA Translation: BAF84098.1
AC090520 Genomic DNA No translation available.
AC009274 Genomic DNA No translation available.
AC007938 Genomic DNA No translation available.
CH236950 Genomic DNA Translation: EAL24085.1
CH471070 Genomic DNA Translation: EAW83769.1
BC017443 mRNA Translation: AAH17443.2
BC110796 mRNA Translation: AAI10797.1
CCDSiCCDS75662.1 [Q9UBF2-1]
CCDS78275.1 [Q9UBF2-2]
RefSeqiNP_001276962.1, NM_001290033.1 [Q9UBF2-2]
NP_036265.3, NM_012133.5 [Q9UBF2-1]

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGridi117926, 48 interactors
IntActiQ9UBF2, 23 interactors
MINTiQ9UBF2
STRINGi9606.ENSP00000402346

PTM databases

iPTMnetiQ9UBF2
PhosphoSitePlusiQ9UBF2

Polymorphism and mutation databases

BioMutaiCOPG2

Proteomic databases

EPDiQ9UBF2
jPOSTiQ9UBF2
MassIVEiQ9UBF2
MaxQBiQ9UBF2
PaxDbiQ9UBF2
PeptideAtlasiQ9UBF2
PRIDEiQ9UBF2
ProteomicsDBi83955 [Q9UBF2-1]

Genome annotation databases

EnsembliENST00000330992; ENSP00000331218; ENSG00000158623 [Q9UBF2-2]
ENST00000425248; ENSP00000402346; ENSG00000158623 [Q9UBF2-1]
GeneIDi26958
KEGGihsa:26958
UCSCiuc033ahl.2 human [Q9UBF2-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
26958
DisGeNETi26958

GeneCards: human genes, protein and diseases

More...
GeneCardsi
COPG2
HGNCiHGNC:2237 COPG2
HPAiHPA045712
MIMi604355 gene
neXtProtiNX_Q9UBF2
OpenTargetsiENSG00000158623
PharmGKBiPA26753

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1078 Eukaryota
COG5240 LUCA
GeneTreeiENSGT00390000016313
InParanoidiQ9UBF2
KOiK17267
OMAiRTIVECM
OrthoDBi255234at2759
PhylomeDBiQ9UBF2

Enzyme and pathway databases

ReactomeiR-HSA-6807878 COPI-mediated anterograde transport
R-HSA-6811434 COPI-dependent Golgi-to-ER retrograde traffic

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
COPG2 human

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
COPG2

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
26958
PharosiQ9UBF2

Protein Ontology

More...
PROi
PR:Q9UBF2

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000158623 Expressed in 161 organ(s), highest expression level in right adrenal gland
ExpressionAtlasiQ9UBF2 baseline and differential
GenevisibleiQ9UBF2 HS

Family and domain databases

Gene3Di1.25.10.10, 1 hit
2.60.40.1480, 1 hit
3.30.310.10, 1 hit
InterProiView protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR002553 Clathrin/coatomer_adapt-like_N
IPR013041 Clathrin_app_Ig-like_sf
IPR009028 Coatomer/calthrin_app_sub_C
IPR032154 Coatomer_g_Cpla
IPR017106 Coatomer_gsu
IPR013040 Coatomer_gsu_app_Ig-like_dom
IPR037067 Coatomer_gsu_app_sf
IPR012295 TBP_dom_sf
PANTHERiPTHR10261 PTHR10261, 1 hit
PfamiView protein in Pfam
PF01602 Adaptin_N, 1 hit
PF16381 Coatomer_g_Cpla, 1 hit
PF08752 COP-gamma_platf, 1 hit
PIRSFiPIRSF037093 Coatomer_gamma_subunit, 1 hit
SUPFAMiSSF48371 SSF48371, 1 hit
SSF49348 SSF49348, 1 hit
SSF55711 SSF55711, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCOPG2_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9UBF2
Secondary accession number(s): A6NH74
, Q2NLA0, Q54AC3, Q8WVW8
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 21, 2001
Last sequence update: May 1, 2000
Last modified: October 16, 2019
This is version 157 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. SIMILARITY comments
    Index of protein domains and families
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  5. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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