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Entry version 148 (16 Oct 2019)
Sequence version 2 (07 Feb 2006)
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Protein

Protein roadkill

Gene

rdx

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Involved in segment polarity. In complex with gft/CUL3, promotes ubiquitination of ci and its subsequent degradation by the proteasome, which results in hh signaling attenuation. This regulation may be important during eye formation for proper packing of ommatidia into a hexagonal array.2 Publications

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: protein ubiquitination

This protein is involved in the pathway protein ubiquitination, which is part of Protein modification.
View all proteins of this organism that are known to be involved in the pathway protein ubiquitination and in Protein modification.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDevelopmental protein, Segmentation polarity protein
Biological processUbl conjugation pathway

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-DME-216167 Nuclear CI is degraded
R-DME-5632684 Hedgehog 'on' state

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...
SignaLinki
Q9VFP2

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...
UniPathwayi
UPA00143

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein roadkill
Alternative name(s):
Hh-induced MATH and BTB domain-containing protein
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:rdx
Synonyms:HIB
ORF Names:CG12537
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3R

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0264493 rdx

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002745931 – 829Protein roadkillAdd BLAST829

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9VFP2

PRoteomics IDEntifications database

More...
PRIDEi
Q9VFP2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed near the anterio-posterior compartment boundary of antenna, leg and wing disks.1 Publication

<p>This subsection of the ‘Expression’ section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified ‘at the protein level’.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Expressed maternally in stage 1 embryos. Isoform 1 and isoform 4 are expressed zygotically in stage 4 in pole cells. By stage 8, expressed in 14 segmentally repeating stripes. During stage 9 and 10, expression appears in neuroblasts. After stage 14, expression is restricted to clypeolabrum, anal plate and salivary glands.1 Publication

<p>This subsection of the ‘Expression’ section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

By hh during segmentation.2 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0264493 Expressed in 65 organ(s), highest expression level in egg chamber

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9VFP2 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9VFP2 DM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with ci and gft/CUL3.

1 Publication

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
66781, 50 interactors

Database of interacting proteins

More...
DIPi
DIP-29550N

Protein interaction database and analysis system

More...
IntActi
Q9VFP2, 11 interactors

STRING: functional protein association networks

More...
STRINGi
7227.FBpp0099767

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9VFP2

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini486 – 616MATHPROSITE-ProRule annotationAdd BLAST131
Domaini655 – 722BTBPROSITE-ProRule annotationAdd BLAST68

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi31 – 36Poly-Gln6
Compositional biasi82 – 86Poly-Ser5
Compositional biasi109 – 145Gln-richAdd BLAST37
Compositional biasi156 – 195Ala-richAdd BLAST40
Compositional biasi208 – 395Ser-richAdd BLAST188
Compositional biasi289 – 387His-richAdd BLAST99

<p>This subsection of the ‘Family and domains’ section provides general information on the biological role of a domain. The term ‘domain’ is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The MATH domain interacts with ci.
The BTB (POZ) domain interacts with gft/CUL3.

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the Tdpoz family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1987 Eukaryota
ENOG410XQV8 LUCA

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9VFP2

KEGG Orthology (KO)

More...
KOi
K10523

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9VFP2

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.210.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000210 BTB/POZ_dom
IPR002083 MATH/TRAF_dom
IPR011333 SKP1/BTB/POZ_sf
IPR008974 TRAF-like

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00651 BTB, 1 hit
PF00917 MATH, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00225 BTB, 1 hit
SM00061 MATH, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49599 SSF49599, 1 hit
SSF54695 SSF54695, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50097 BTB, 1 hit
PS50144 MATH, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 4 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1Curated (identifier: Q9VFP2-1) [UniParc]FASTAAdd to basket
Also known as: EImported

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MFEPYVKIKK KRSVNEIYEN ENLEQQQHHL QQQQQQPATS DNCCCENGEP
60 70 80 90 100
QNAPEVATAT VAATSVAATS AAATVATGAA ASSSSSGNCS RLQQLISTPP
110 120 130 140 150
VLLRRSSLQQ QQHQQQQHHP HTPAATATPP QQQQQQQAAP SVLQQHLGHL
160 170 180 190 200
NYESGATAAA AATAAAAAAT VATSRSGSAT LAQHLATPSN ILQAAFGSSN
210 220 230 240 250
LQHILTRSAP SPSSSAISSN NCSSACAGNT HYNGGNSNSG SSSSNSNHHS
260 270 280 290 300
NSIIASRLFG AASSSSSSSS SSASASSSSV AASSSSSSHH LHSHHSALTN
310 320 330 340 350
SITNRINQSI RRHLNQQQHH HPLSASSSSA SASPSASTSS SSSYQQSSVQ
360 370 380 390 400
QQHYNCAHPA QQQQHHHHHH SSSSSSSSSS SSSHHHHNSS SSSNSNNQQQ
410 420 430 440 450
PQQSPLCLVL LVKCPNSKEF CNAAANFCDK RLPVNECQAS QTARVTSNLH
460 470 480 490 500
ASSSTMAVSR VPSPPLPEVN TPVAENWCYT QVKVVKFSYM WTINNFSFCR
510 520 530 540 550
EEMGEVLKSS TFSAGANDKL KWCLRVNPKG LDEESKDYLS LYLLLVSCNK
560 570 580 590 600
SEVRAKFKFS ILNAKREETK AMESQRAYRF VQGKDWGFKK FIRRDFLLDE
610 620 630 640 650
ANGLLPEDKL TIFCEVSVVA DSVNISGQSN IVQFKVPECK LSEDLGNLFD
660 670 680 690 700
NEKFSDVTLS VGGREFQAHK AILAARSDVF AAMFEHEMEE RKLNRVAITD
710 720 730 740 750
VDHEVLKEML RFIYTGKAPN LEKMADDLLA AADKYALEKL KVMCEEALCV
760 770 780 790 800
NLSVETAAET LILADLHSAD QLKAQTIDFI NTHATDVMET SGWQNMITTH
810 820
SHLIAEAFRA LATQQIPPIG PPRKRVKMS
Length:829
Mass (Da):89,667
Last modified:February 7, 2006 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i608D32B45859280E
GO
Isoform 2Curated (identifier: Q9VFP2-2) [UniParc]FASTAAdd to basket
Also known as: BImported

The sequence of this isoform differs from the canonical sequence as follows:
     1-455: Missing.

Show »
Length:374
Mass (Da):42,284
Checksum:i2116548EE64F04C0
GO
Isoform 3Curated (identifier: Q9VFP2-3) [UniParc]FASTAAdd to basket
Also known as: CImported

The sequence of this isoform differs from the canonical sequence as follows:
     1-426: Missing.
     427-430: FCDK → MALA

Show »
Length:403
Mass (Da):45,310
Checksum:i190BB5EC3B108CD8
GO
Isoform 4Curated (identifier: Q9VFP2-4) [UniParc]FASTAAdd to basket
Also known as: AImported, FImported

The sequence of this isoform differs from the canonical sequence as follows:
     1-423: Missing.
     424-430: AANFCDK → MDLIQEP

Show »
Length:406
Mass (Da):45,750
Checksum:i344A5EA7A271D404
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti536K → T in ABG24573 (PubMed:16651542).Curated1
Sequence conflicti716G → D in ABG24573 (PubMed:16651542).Curated1
Sequence conflicti749 – 750CV → WL in ABG24573 (PubMed:16651542).Curated2

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0228251 – 455Missing in isoform 2. 1 PublicationAdd BLAST455
Alternative sequenceiVSP_0228261 – 426Missing in isoform 3. 1 PublicationAdd BLAST426
Alternative sequenceiVSP_0228271 – 423Missing in isoform 4. CuratedAdd BLAST423
Alternative sequenceiVSP_022828424 – 430AANFCDK → MDLIQEP in isoform 4. Curated7
Alternative sequenceiVSP_022829427 – 430FCDK → MALA in isoform 3. 1 Publication4

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
DQ507278 mRNA Translation: ABG24573.1
AE014297 Genomic DNA Translation: AAF55007.3
AE014297 Genomic DNA Translation: AAF55008.2
AE014297 Genomic DNA Translation: AAN14346.1
AE014297 Genomic DNA Translation: AAN14347.2
AE014297 Genomic DNA Translation: AAN14348.1
AY121682 mRNA Translation: AAM52009.1
BT012443 mRNA Translation: AAS93714.1
BT021321 mRNA Translation: AAX33469.1

NCBI Reference Sequences

More...
RefSeqi
NP_650325.1, NM_142068.2 [Q9VFP2-3]
NP_650326.3, NM_142069.4 [Q9VFP2-1]
NP_731875.2, NM_169564.2 [Q9VFP2-4]
NP_731876.2, NM_169565.2 [Q9VFP2-4]
NP_731877.1, NM_169566.2 [Q9VFP2-2]

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0100361; FBpp0099767; FBgn0264493 [Q9VFP2-1]
FBtr0301632; FBpp0290846; FBgn0264493 [Q9VFP2-4]
FBtr0301633; FBpp0290847; FBgn0264493 [Q9VFP2-2]
FBtr0301634; FBpp0290848; FBgn0264493 [Q9VFP2-3]
FBtr0334298; FBpp0306413; FBgn0264493 [Q9VFP2-4]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
41704

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dme:Dmel_CG12537

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ507278 mRNA Translation: ABG24573.1
AE014297 Genomic DNA Translation: AAF55007.3
AE014297 Genomic DNA Translation: AAF55008.2
AE014297 Genomic DNA Translation: AAN14346.1
AE014297 Genomic DNA Translation: AAN14347.2
AE014297 Genomic DNA Translation: AAN14348.1
AY121682 mRNA Translation: AAM52009.1
BT012443 mRNA Translation: AAS93714.1
BT021321 mRNA Translation: AAX33469.1
RefSeqiNP_650325.1, NM_142068.2 [Q9VFP2-3]
NP_650326.3, NM_142069.4 [Q9VFP2-1]
NP_731875.2, NM_169564.2 [Q9VFP2-4]
NP_731876.2, NM_169565.2 [Q9VFP2-4]
NP_731877.1, NM_169566.2 [Q9VFP2-2]

3D structure databases

SMRiQ9VFP2
ModBaseiSearch...

Protein-protein interaction databases

BioGridi66781, 50 interactors
DIPiDIP-29550N
IntActiQ9VFP2, 11 interactors
STRINGi7227.FBpp0099767

Proteomic databases

PaxDbiQ9VFP2
PRIDEiQ9VFP2

Genome annotation databases

EnsemblMetazoaiFBtr0100361; FBpp0099767; FBgn0264493 [Q9VFP2-1]
FBtr0301632; FBpp0290846; FBgn0264493 [Q9VFP2-4]
FBtr0301633; FBpp0290847; FBgn0264493 [Q9VFP2-2]
FBtr0301634; FBpp0290848; FBgn0264493 [Q9VFP2-3]
FBtr0334298; FBpp0306413; FBgn0264493 [Q9VFP2-4]
GeneIDi41704
KEGGidme:Dmel_CG12537

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
5962
FlyBaseiFBgn0264493 rdx

Phylogenomic databases

eggNOGiKOG1987 Eukaryota
ENOG410XQV8 LUCA
InParanoidiQ9VFP2
KOiK10523
PhylomeDBiQ9VFP2

Enzyme and pathway databases

UniPathwayiUPA00143
ReactomeiR-DME-216167 Nuclear CI is degraded
R-DME-5632684 Hedgehog 'on' state
SignaLinkiQ9VFP2

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
rdx fly

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
41704

Protein Ontology

More...
PROi
PR:Q9VFP2

Gene expression databases

BgeeiFBgn0264493 Expressed in 65 organ(s), highest expression level in egg chamber
ExpressionAtlasiQ9VFP2 baseline and differential
GenevisibleiQ9VFP2 DM

Family and domain databases

Gene3Di2.60.210.10, 1 hit
InterProiView protein in InterPro
IPR000210 BTB/POZ_dom
IPR002083 MATH/TRAF_dom
IPR011333 SKP1/BTB/POZ_sf
IPR008974 TRAF-like
PfamiView protein in Pfam
PF00651 BTB, 1 hit
PF00917 MATH, 1 hit
SMARTiView protein in SMART
SM00225 BTB, 1 hit
SM00061 MATH, 1 hit
SUPFAMiSSF49599 SSF49599, 1 hit
SSF54695 SSF54695, 1 hit
PROSITEiView protein in PROSITE
PS50097 BTB, 1 hit
PS50144 MATH, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRDX_DROME
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9VFP2
Secondary accession number(s): A4V2V6
, Q15BT8, Q5BIA3, Q7KSK6, Q8ING4, Q8MRB4, Q9VFP3
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 6, 2007
Last sequence update: February 7, 2006
Last modified: October 16, 2019
This is version 148 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  3. PATHWAY comments
    Index of metabolic and biosynthesis pathways
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