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UniProtKB - S4RDD6 (S4RDD6_PETMA)

Entry version 28 (31 Jul 2019)
Sequence version 1 (18 Sep 2013)
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Protein
Submitted name:

Nodal modulator

Gene
N/A
Organism
Petromyzon marinus (Sea lamprey)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Nodal modulatorImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPetromyzon marinus (Sea lamprey)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7757 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Cyclostomata › Hyperoartia › Petromyzontiformes › Petromyzontidae › Petromyzon
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000245300 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni640 – 670DisorderedSequence analysisAdd BLAST31

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG1948 Eukaryota
ENOG410XTI0 LUCA

Ensembl GeneTree

More...GeneTreei		ENSGT00390000000089

Identification of Orthologs from Complete Genome Data

More...OMAi		GWSFEPE

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR013784 Carb-bd-like_fold

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF49452 SSF49452, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

S4RDD6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
SSAQIKLYTK QGNLKYQTDC APNNGYFMIP LYDKGDFTLK IEPPLGWSFE 
        60         70         80         90        100
PSSVELHVDG ATDPCSTGDD IDFLFTGFSV AGRVLSRNME SGPAGVLVEL 
       110        120        130        140        150
TVGGDTLQSV HTQPGGRYSF GRVHPGEYEV KASHPTWTLQ PASVAVTVGV 
       160        170        180        190        200
ANGNAGEGLV VAGYQVTGSV RSEDEPVQGV QLLLFSSSVT QQDVAGCSLG 
       210        220        230        240        250
PVKGFSAAST LPAFVCSTTS THAGTFMFPS LPCGSYSLVP FYQGERITFD 
       260        270        280        290        300
VAPARLDFTV EHDSLSLATV FRVMGFSVTG RVLEAVGGNG IPGAVVSLNN 
       310        320        330        340        350
IQAVVTREDG SFRLENMTTG SYTIATSKEH YSFPPVSSKI APSTPTLPDI 
       360        370        380        390        400
VASSFSVCGT VSVDRLPEGG RGGGRRRVTL TPVGGAAPTE ASETDALGAF 
       410        420        430        440        450
CFLAAPGTYG LQVDVSEAES KAGLALQPAL LTVTVTRAPV LGLSFTQLLL 
       460        470        480        490        500
SLSGTVSCLA GCGELALTLQ HAAPQGEKRS LSLSDSGPVA DFFFDRLLLG 
       510        520        530        540        550
RYKVSVGQEE WCWKNRSLEV ELLESGGGGH VEFRQTGFML RCSLSHSIAL 
       560        570        580        590        600
EFYQDEKGPE NVGVYNLTKG MNRFCLSLPG MYKLTPRSCH RFQQDVYTYD 
       610        620        630        640        650
TAHPSVLAMT ATHHLVQGAI VTDKMAADIT LTVHSARGTR GAARVGPRRK 
       660        670        680        690        700
HRSRTCEPES RHRTSASGAV RSQRDYIKMQ PLAVLGCVPL VQQCFLTIVV 
       710        720        730        740        750
SFHFDAGEKV RVEAASRELL FHPASTEAVV QGESCPEQLA AVSGEAGVFV 
       760        770        780        790        800
AGRVEPALPG VVIDVRESGA ADSLVTVLTD EHGSYRVGPL QGHRDYVVSA 
       810        820        830        840        850
AKEGFVLRPV DGRHGHFQAF ALASITLTIT AEDGQPLSGV LLSLSGGQFR 
       860        870        880        890        900
SNRLTQDNGS YKFTNLTPGQ FFFKPMMKEF RFEPSSQVVD VQEGHAVHID 
       910        920        930        940        950
VSAFRVAYRC FGWVWSLSGE AEAGVGVEAV GQGACGTSVE ESATDEEGRF 
       960        970        980        990       1000
RLRGLTPSCT YHVRVKREGN DHVERAIPHY RAVQVDTRDI HDVNIVAFRH 
      1010       1020       1030       1040       1050
MNQFDLSGNI ITPSQELLAT LKVVLYRGEN LDTPFQTLSL TQSSFFHFPP 
      1060       1070       1080       1090       1100
LQRDGESYTM ALESSLPRAL YEFSLPEVSF STAGFHKHVT LSFSPRRKAM 
      1110       1120       1130       1140       1150
EQEASQGSYL ALPLTLLLLI AIYNHDKALP MLWQLGSRVQ AVQAMGPPFG 
      1160       1170
AAPAVEDAKK LLKKPKSRRT
Length:1,170
Mass (Da):126,026
Last modified:September 18, 2013 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i5D90F37F1C386B5A
GO

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSPMAT00000003233; ENSPMAP00000003218; ENSPMAG00000002907

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Genome annotation databases

EnsembliENSPMAT00000003233; ENSPMAP00000003218; ENSPMAG00000002907

Phylogenomic databases

eggNOGiKOG1948 Eukaryota
ENOG410XTI0 LUCA
GeneTreeiENSGT00390000000089
OMAiGWSFEPE

Family and domain databases

InterProiView protein in InterPro
IPR013784 Carb-bd-like_fold
SUPFAMiSSF49452 SSF49452, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiS4RDD6_PETMA
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: S4RDD6
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: September 18, 2013
Last sequence update: September 18, 2013
Last modified: July 31, 2019
This is version 28 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health

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