"In this study we found that the levels of sSEMA4A were significantly elevated in patients with CRSwNPs and asthma and that SEMA4A was especially highly expressed in eosinophils in nasal polyps. We also demonstrated that SEMA4A in eosinophils can be cleaved by ADAMTS4 suggesting that eosinophils are a major source of SEMA4A in serum from these patients."xsd:string