"We identified 32 compound heterozygous mutations and 9 homozygous mutations in IL10 receptor subunit alpha and 1 homozygous mutation in IL10 receptor subunit beta. Among these mutations 10 novel mutations were identified and 6 pathogenic mutations had been previously described. In patients with IL10 receptor subunit alpha mutations c.301C>T (p.R101RW) and c.537 G>A (p.T179T) were the most common mutations."xsd:string