"The anaphase-promoting complex/cyclosome (APC/C) is suppressed by the small pseudosubstrate inhibitor Acm1. Acm1 D-box extension inhibits reaction processivity by perturbing the normal interaction with Doc1/Apc10. These results reveal a simple elegant mode of pseudosubstrate inhibition that combines high-affinity activator binding with specific disruption of Doc1/Apc10 function in processive ubiquitylation."xsd:string