"Detailed cell fractionation immunoprecipitation microscopy and immunohistochemical analyses demonstrated that CDCP1 promotes translocation of the key regulators of Wnt signaling b-catenin and E-cadherin to the nucleus. Of functional importance disruption of CDCP1 reduces nuclear localized chromatin-associated b-catenin and nuclear localized E-cadherin increases sequestration of these proteins in cell membranes"xsd:string