"We found that pro-inflammatory cytokines IL-6 and CCL2 suppressed PER2 gene expression. Mechanistic studies further revealed that IL-6/STAT3/NFkappaB p50 and CCL2/PI3K/AKT signaling pathways suppressed PER2 gene expression in both phenotypically normal MCF-10A cells as well as MCF-7 breast cancer cells."xsd:string