"Following an intratracheal challenge with S. pneumoniae Zcchc6 deficiency led to a modest but significant increase in the expression of select cytokines including IL-6 CXCL1 and CXCL5. These findings were recapitulated in vitro whereby Zcchc6-deficient macrophages exhibited similar increases in cytokine expression due to bacterial stimulation"xsd:string