"Study in ApoE-/- transgenic mice expressing alpha-def-1 revealed that alpha-def-1 lowers total plasma cholesterol and decreases lesion size. However lesion size was larger than in mice with total plasma cholesterol lowered to the same extent by inhibiting its adsorption or by ingesting a low-fat diet. alpha-def-1 levels correlated independently with lesion size in ApoE-/- mice. alpha-def-1 has competing effects on ath..."xsd:string