"Here we show that succinate accumulation induced by SDHB loss of function increased the expression of zinc finger protein 148 (ZNF148 also named ZBP-89) in astrointestinal stromal tumor (GIST) cells. Meanwhile ZNF148 is found to be phosphorylated by ERK at Ser306 and this phosphorylation results in ZNF148 binding to Forkhead box M1 (FOXM1)."xsd:string