"CC genotype of rs3816527 had an obviously higher frequency in cases than in controls and had a positive effect on AS occurrence and the same was true of the C allele in rs3816527. For rs3845978 CT genotype showed a significant frequency difference between the case and control groups (P=0.03) and people with genotypes carrying the T allele developed AS earlier ) and the same was found in the analysis of the T allele."xsd:string