"Study observed a significant decrease of miRNA-101 intracellular levels in everolimus-resistant clear cell renal cell carcinoma cell line (786-OR) and significant increase of HIF-2alpha in 786-OR. The circulating levels of miRNA-101 may be a potential biomarker of anti-mTOR therapy response and resistance prediction. Moreover the resistance to mTOR inhibitors seems to be related with the overexpression of HIF-2alpha."xsd:string