"Observational study of gene-disease association. (HuGE Navigator); 4 new CBS mutations c.451G>A (p.Gly151?) c.740_769del (p.Lys247_Gly256del) c.862G>C (p.Ala288Pro) and c.1135C>T (p.Arg379Trp)were found. The CBS c.1224-2A>C allele confers vitamin B6 nonresponsiveness."xsd:string