"Function: DJ-1/PARK7 destroys a reactive breakdown product of the glycolytic metabolite 1,3-bisphosphoglycerate. The reactive intermediate modifies amino groups of metabolites and proteins with phosphoglycerate. DJ-1/PARK7 deficiency leads to accumulation of phosphoglycerate and glycerate modifications in several model systems, including human cell lines, mouse brain and Drosophila melanogaster. Disease: Parkinson's disease."xsd:string