"Inhibition of chaperone ATPase (Hsp104) by gadolinium chloride (GdHCl) leads to reduced aggregation of the protein. Under in vitro conditions trehalose is able to restore the GdHCl-induced loss of ATPase activity of recombinant Hsp104 to its original level. Inactivation of Hsp104 at the stage when oligomers have already been formed increases the rate of formation of aggregates by inhibiting disaggregation of oligomers."xsd:string