"treatment downregulated the expression of JAK1 JAK3 and STAT3 and upregulated cytosolic nuclear factor (NF)kappaB p65 and IkappaB. In conclusion the results of the present study indicated that curculigoside exhibited significant antiarthritic effects in vivo and in vitro and the molecular mechanism may be associated with the JAK/STAT/NFkappaB signaling pathway."xsd:string