"The S. cerevisiae (Sc) Idp1 Idp2 and Idp3 are highly similar to Homo sapiens (Hs) Idh1 and Idh2 (67 60 and 59% amino acid identity between Sc Idp1 Idp2 and Idp3 and Hs Idh1 respectively) and the arginine residues corresponding to R100 and R132 in Hs Idh1 (Hs Idh2 R140 and R172) are conserved in the corresponding yeast orthologs"xsd:string