"Here we highlight our recent study of a novel RPA-binding protein Regulator of Ty1 transposition 105 (Rtt105) in Saccharomyces cerevisiae which regulates the RPA-ssDNA platform assembly at replication forks. We propose that Rtt105 functions as an "RPA chaperone" during DNA replication likely also promoting the assembly of RPA-ssDNA platform in other processes in which RPA plays a critical role."xsd:string