"pros-1 deletion mutants exhibited larval lethality pros-1 and human Prox1 transgenes were able to rescue the larval lethal phenotype. the structure and functions of sensory neurons such as the morphology of sensory endings sensory behavior and sensory-mediated cold tolerance appeared to be affected by the pros-1 RNAi. Together our results show that the C. elegans PROS-1 is a transcriptional regulator in the glia"xsd:string