"Data report a novel noncanonical function of WARS in antiviral defense. WARS is rapidly secreted in response to viral infection and primes the innate immune response by inducing the secretion of proinflammatory cytokines and type I IFNs resulting in the inhibition of virus replication both in vitro and in vivo. These results suggest that WARS is a member of the antiviral innate immune response."xsd:string