"We conclude that DOCK8 protein is expressed in resting human neutrophils and DOCK8 expression is increased after stimulation with either phorbol 12-myristate 13-acetate or N-Formylmethionyl-leucyl-phenylalanine. Most patients with a disease-causing mutation in DOCK8 have normal neutrophil functions while a minority showed a mild to moderate chemotactic defect."xsd:string