"Bioinformatics analysis of protein structure and known mutations in CYP21A2 gene in congenital adrenal hyperplasia demonstrate that most of the SNPs shows no biological implications. However the study proposes a putative pathogenic effect of five novel mutations p.L107Q p.L122R p.R132H p.P335L and p.H466fs found in 21-hydroxylase deficient patients."xsd:string