"Deleting the Prkca gene which encodes PKCalpha reverses diabetes-induced autophagy impairment cellular organelle stress and apoptosis leading to an NTD reduction. PKCalpha increases the expression of miR-129-2 which is a negative regulator of autophagy. miR-129-2 represses autophagy by directly targeting PGC-1alpha a positive regulator for mitochondrial function which is disturbed by maternal diabetes."xsd:string