"p21-associated inhibition of early-stage malignant progression and the intense expression in papilloma outgrowths identifies a novel significant antagonism between p21 and ras(Ha)/ROCK2/NF-kappaB signalling in skin carcinogenesis.these data show that ROCK2 activation induces malignancy in ras(Ha)-initiated/promoted papillomas in the context of p53 loss and novel NF-kappaB expression"xsd:string