"NCAPD2 and NCAPD3 expression levels have been confirmed to be significantly up-regulated in the intestinal mucosa of patients with active ulcerative colitis. In vitro the data suggested that silencing NACPD2 and NACPD3 could depress the expression of IL-1beta IL-6 and TNF-alpha. Further knockdown of NACPD2 and NACPD3 could remarkably suppress IKK nucleation and NF-kappaB volume."xsd:string