http://purl.uniprot.org/citations/10021768 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/10021768 | http://www.w3.org/2000/01/rdf-schema#comment | "The genes encoding the three major targets of conventional insecticides are: Rdl, which encodes a gamma-aminobutyric acid receptor subunit (RDL); para, which encodes a voltage-gated sodium channel (PARA); and Ace, which encodes insect acetylcholinesterase (AChE). Interestingly, despite the complexity of the encoded receptors or enzymes, very few amino acid residues are replaced in different resistant insects: one within RDL, two within PARA and three or more within AChE. Here we examine the possible reasons underlying this extreme conservation by looking at the aspects of receptor and/or enzyme function that may constrain replacements to such a limited number of residues."xsd:string |
http://purl.uniprot.org/citations/10021768 | http://purl.org/dc/terms/identifier | "doi:10.1098/rstb.1998.0319"xsd:string |
http://purl.uniprot.org/citations/10021768 | http://purl.uniprot.org/core/author | "ffrench-Constant R.H."xsd:string |
http://purl.uniprot.org/citations/10021768 | http://purl.uniprot.org/core/author | "Pittendrigh B."xsd:string |
http://purl.uniprot.org/citations/10021768 | http://purl.uniprot.org/core/author | "Vaughan A."xsd:string |
http://purl.uniprot.org/citations/10021768 | http://purl.uniprot.org/core/author | "Anthony N."xsd:string |
http://purl.uniprot.org/citations/10021768 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
http://purl.uniprot.org/citations/10021768 | http://purl.uniprot.org/core/name | "Philos Trans R Soc Lond B Biol Sci"xsd:string |
http://purl.uniprot.org/citations/10021768 | http://purl.uniprot.org/core/pages | "1685-1693"xsd:string |
http://purl.uniprot.org/citations/10021768 | http://purl.uniprot.org/core/title | "Why are there so few resistance-associated mutations in insecticide target genes?"xsd:string |
http://purl.uniprot.org/citations/10021768 | http://purl.uniprot.org/core/volume | "353"xsd:string |
http://purl.uniprot.org/citations/10021768 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/10021768 |
http://purl.uniprot.org/citations/10021768 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/10021768 |
http://purl.uniprot.org/uniprot/#_A0A0B4KGI5-mappedCitation-10021768 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/10021768 |
http://purl.uniprot.org/uniprot/#_E1JIJ8-mappedCitation-10021768 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/10021768 |
http://purl.uniprot.org/uniprot/#_B7Z0Z2-mappedCitation-10021768 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/10021768 |
http://purl.uniprot.org/uniprot/#_M9MSE6-mappedCitation-10021768 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/10021768 |
http://purl.uniprot.org/uniprot/#_M9MSE7-mappedCitation-10021768 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/10021768 |
http://purl.uniprot.org/uniprot/#_M9MSE9-mappedCitation-10021768 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/10021768 |
http://purl.uniprot.org/uniprot/#_M9MSF1-mappedCitation-10021768 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/10021768 |
http://purl.uniprot.org/uniprot/#_M9MSF2-mappedCitation-10021768 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/10021768 |
http://purl.uniprot.org/uniprot/#_M9MSP1-mappedCitation-10021768 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/10021768 |
http://purl.uniprot.org/uniprot/#_M9MSP2-mappedCitation-10021768 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/10021768 |
http://purl.uniprot.org/uniprot/#_M9MSP3-mappedCitation-10021768 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/10021768 |