| http://purl.uniprot.org/citations/10023771 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10023771 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10023771 | http://www.w3.org/2000/01/rdf-schema#comment | "Two synthetic O-GlcNAc-bearing peptides that elicit H-2Db-restricted glycopeptide-specific cytotoxic T cells (CTL) have been shown to display nonreciprocal patterns of cross-reactivity. Here, we present the crystal structures of the H-2Db glycopeptide complexes to 2.85 A resolution or better. In both cases, the glycan is solvent exposed and available for direct recognition by the T cell receptor (TCR). We have modeled the complex formed between the MHC-glycopeptide complexes and their respective TCRs, showing that a single saccharide residue can be accommodated in the standard TCR-MHC geometry. The models also reveal a possible molecular basis for the observed cross-reactivity patterns of the CTL clones, which appear to be influenced by the length of the CDR3 loop and the nature of the immunizing ligand."xsd:string |
| http://purl.uniprot.org/citations/10023771 | http://purl.org/dc/terms/identifier | "doi:10.1016/s1074-7613(00)80007-2"xsd:string |
| http://purl.uniprot.org/citations/10023771 | http://purl.org/dc/terms/identifier | "doi:10.1016/s1074-7613(00)80007-2"xsd:string |
| http://purl.uniprot.org/citations/10023771 | http://purl.uniprot.org/core/author | "Edwards J."xsd:string |
| http://purl.uniprot.org/citations/10023771 | http://purl.uniprot.org/core/author | "Edwards J."xsd:string |
| http://purl.uniprot.org/citations/10023771 | http://purl.uniprot.org/core/author | "Jones E.Y."xsd:string |
| http://purl.uniprot.org/citations/10023771 | http://purl.uniprot.org/core/author | "Jones E.Y."xsd:string |
| http://purl.uniprot.org/citations/10023771 | http://purl.uniprot.org/core/author | "Elliott T."xsd:string |
| http://purl.uniprot.org/citations/10023771 | http://purl.uniprot.org/core/author | "Elliott T."xsd:string |
| http://purl.uniprot.org/citations/10023771 | http://purl.uniprot.org/core/author | "Dwek R.A."xsd:string |
| http://purl.uniprot.org/citations/10023771 | http://purl.uniprot.org/core/author | "Dwek R.A."xsd:string |
| http://purl.uniprot.org/citations/10023771 | http://purl.uniprot.org/core/author | "Tormo J."xsd:string |
| http://purl.uniprot.org/citations/10023771 | http://purl.uniprot.org/core/author | "Tormo J."xsd:string |
| http://purl.uniprot.org/citations/10023771 | http://purl.uniprot.org/core/author | "Arsequell G."xsd:string |
| http://purl.uniprot.org/citations/10023771 | http://purl.uniprot.org/core/author | "Arsequell G."xsd:string |
| http://purl.uniprot.org/citations/10023771 | http://purl.uniprot.org/core/author | "Glithero A."xsd:string |
| http://purl.uniprot.org/citations/10023771 | http://purl.uniprot.org/core/author | "Glithero A."xsd:string |
| http://purl.uniprot.org/citations/10023771 | http://purl.uniprot.org/core/author | "Haurum J.S."xsd:string |
| http://purl.uniprot.org/citations/10023771 | http://purl.uniprot.org/core/author | "Haurum J.S."xsd:string |
| http://purl.uniprot.org/citations/10023771 | http://purl.uniprot.org/core/author | "Pao Y.L."xsd:string |
| http://purl.uniprot.org/citations/10023771 | http://purl.uniprot.org/core/author | "Pao Y.L."xsd:string |
| http://purl.uniprot.org/citations/10023771 | http://purl.uniprot.org/core/author | "Springer S."xsd:string |
| http://purl.uniprot.org/citations/10023771 | http://purl.uniprot.org/core/author | "Springer S."xsd:string |