| http://purl.uniprot.org/citations/10023777 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10023777 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10023777 | http://www.w3.org/2000/01/rdf-schema#comment | "An interleukin-18 binding protein (IL-18BP) was purified from urine by chromatography on IL-18 beads, sequenced, cloned, and expressed in COS7 cells. IL-18BP abolished IL-18 induction of interferon-gamma (IFNgamma), IL-8, and activation of NF-kappaB in vitro. Administration of IL-18BP to mice abrogated circulating IFNgamma following LPS. Thus, IL-18BP functions as an inhibitor of the early Th1 cytokine response. IL-18BP is constitutively expressed in the spleen, belongs to the immunoglobulin superfamily, and has limited homology to the IL-1 type II receptor. Its gene was localized on human chromosome 11q13, and no exon coding for a transmembrane domain was found in an 8.3 kb genomic sequence. Several Poxviruses encode putative proteins highly homologous to IL-18BP, suggesting that viral products may attenuate IL-18 and interfere with the cytotoxic T cell response."xsd:string |
| http://purl.uniprot.org/citations/10023777 | http://purl.org/dc/terms/identifier | "doi:10.1016/s1074-7613(00)80013-8"xsd:string |
| http://purl.uniprot.org/citations/10023777 | http://purl.org/dc/terms/identifier | "doi:10.1016/s1074-7613(00)80013-8"xsd:string |
| http://purl.uniprot.org/citations/10023777 | http://purl.org/dc/terms/identifier | "doi:10.1016/S1074-7613(00)80013-8"xsd:string |
| http://purl.uniprot.org/citations/10023777 | http://purl.uniprot.org/core/author | "Kim S.-H."xsd:string |
| http://purl.uniprot.org/citations/10023777 | http://purl.uniprot.org/core/author | "Kim S.-H."xsd:string |
| http://purl.uniprot.org/citations/10023777 | http://purl.uniprot.org/core/author | "Novick D."xsd:string |
| http://purl.uniprot.org/citations/10023777 | http://purl.uniprot.org/core/author | "Novick D."xsd:string |
| http://purl.uniprot.org/citations/10023777 | http://purl.uniprot.org/core/author | "Rubinstein M."xsd:string |
| http://purl.uniprot.org/citations/10023777 | http://purl.uniprot.org/core/author | "Rubinstein M."xsd:string |
| http://purl.uniprot.org/citations/10023777 | http://purl.uniprot.org/core/author | "Dinarello C.A."xsd:string |
| http://purl.uniprot.org/citations/10023777 | http://purl.uniprot.org/core/author | "Dinarello C.A."xsd:string |
| http://purl.uniprot.org/citations/10023777 | http://purl.uniprot.org/core/author | "Fantuzzi G."xsd:string |
| http://purl.uniprot.org/citations/10023777 | http://purl.uniprot.org/core/author | "Fantuzzi G."xsd:string |
| http://purl.uniprot.org/citations/10023777 | http://purl.uniprot.org/core/author | "Reznikov L.L."xsd:string |
| http://purl.uniprot.org/citations/10023777 | http://purl.uniprot.org/core/author | "Reznikov L.L."xsd:string |
| http://purl.uniprot.org/citations/10023777 | http://purl.uniprot.org/core/date | "1999"xsd:gYear |
| http://purl.uniprot.org/citations/10023777 | http://purl.uniprot.org/core/date | "1999"xsd:gYear |
| http://purl.uniprot.org/citations/10023777 | http://purl.uniprot.org/core/name | "Immunity"xsd:string |
| http://purl.uniprot.org/citations/10023777 | http://purl.uniprot.org/core/name | "Immunity"xsd:string |
| http://purl.uniprot.org/citations/10023777 | http://purl.uniprot.org/core/pages | "127-136"xsd:string |
| http://purl.uniprot.org/citations/10023777 | http://purl.uniprot.org/core/pages | "127-136"xsd:string |
| http://purl.uniprot.org/citations/10023777 | http://purl.uniprot.org/core/title | "Interleukin-18 binding protein: a novel modulator of the Th1 cytokine response."xsd:string |