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http://purl.uniprot.org/citations/10047538 | http://www.w3.org/2000/01/rdf-schema#comment | "The principal pathway of antigen processing that is associated with MHC class I involves three main steps: cytosolic peptide generation, peptide transport into the endoplasmic reticulum and peptide assembly with class I molecules. Recent advances suggest that additional cytosolic proteases complement the proteasome as a source of antigenic peptides. Peptide assembly involves several novel cofactors - including the proteins tapasin and ERp57, which may be important for stabilisation of empty class I molecules as well as quality control after peptide binding. Finally, genetic evidence suggests an important influence of an unidentified gene, in the MHC complex, on MHC class I processing."xsd:string |
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http://purl.uniprot.org/citations/10047538 | http://purl.uniprot.org/core/author | "van Endert P.M."xsd:string |
http://purl.uniprot.org/citations/10047538 | http://purl.uniprot.org/core/date | "1999"xsd:gYear |
http://purl.uniprot.org/citations/10047538 | http://purl.uniprot.org/core/name | "Curr Opin Immunol"xsd:string |
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http://purl.uniprot.org/citations/10047538 | http://purl.uniprot.org/core/title | "Genes regulating MHC class I processing of antigen."xsd:string |
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