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| http://purl.uniprot.org/citations/10047540 | http://www.w3.org/2000/01/rdf-schema#comment | "Fascinating recent discoveries have focused attention on the nonclassical class I molecules. They can exert their function at most levels of the immune response, being part of both innate and adaptive immune systems. They not only have specialized antigen-presentation functions but also play important immunoregulatory roles: HLA-E regulates natural killer cells by interacting with CD94/NKG2 receptors; the MIC (MHC class I chain related) glycoproteins appear crucial to the activation of gammadelta T cells in the gastrointestinal epithelium; HLA-G may play a role in controlling the immune response to the fetus; and CD1 molecules are important in defense against bacterial infections, as well as in the development and regulation of a subset of NKT cells expressing a highly restricted TCR repertoire; however not all nonclassical class I molecules have an immunological function, as demonstrated by HFE which is implicated in iron metabolism."xsd:string |
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| http://purl.uniprot.org/citations/10047540 | http://purl.uniprot.org/core/author | "McMichael A.J."xsd:string |
| http://purl.uniprot.org/citations/10047540 | http://purl.uniprot.org/core/author | "Allan D.S."xsd:string |
| http://purl.uniprot.org/citations/10047540 | http://purl.uniprot.org/core/author | "Braud V.M."xsd:string |
| http://purl.uniprot.org/citations/10047540 | http://purl.uniprot.org/core/date | "1999"xsd:gYear |
| http://purl.uniprot.org/citations/10047540 | http://purl.uniprot.org/core/name | "Curr Opin Immunol"xsd:string |
| http://purl.uniprot.org/citations/10047540 | http://purl.uniprot.org/core/pages | "100-108"xsd:string |
| http://purl.uniprot.org/citations/10047540 | http://purl.uniprot.org/core/title | "Functions of nonclassical MHC and non-MHC-encoded class I molecules."xsd:string |
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