http://purl.uniprot.org/citations/10051409 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/10051409 | http://www.w3.org/2000/01/rdf-schema#comment | "Severe combined immunodeficiency (scid) mice are deficient in the enzyme DNA-PK (DNA-dependent protein kinase) as a result of the mutation in the gene encoding the catalytic subunit (DNA-PKcs) of this enzyme. DNA-PKcs is a member of the phosphatidylinositol 3-kinase superfamily, which includes the human protein ATM (ataxia telangiectasia mutated) and the yeast protein Tel1. Using Q-FISH (quantitative fluorescence in situ hybridization), we show here that scid mice from four different genetic backgrounds have, on average, 1.5-2 times longer telomeres than those of corresponding wild-type mice. Our results point to the possibility that DNA-PKcs may, directly or indirectly, be involved in telomere length regulation in mammalian cells."xsd:string |
http://purl.uniprot.org/citations/10051409 | http://purl.org/dc/terms/identifier | "doi:10.1006/geno.1998.5668"xsd:string |
http://purl.uniprot.org/citations/10051409 | http://purl.uniprot.org/core/author | "Bryant P."xsd:string |
http://purl.uniprot.org/citations/10051409 | http://purl.uniprot.org/core/author | "Slijepcevic P."xsd:string |
http://purl.uniprot.org/citations/10051409 | http://purl.uniprot.org/core/author | "Silver A."xsd:string |
http://purl.uniprot.org/citations/10051409 | http://purl.uniprot.org/core/author | "Hande P."xsd:string |
http://purl.uniprot.org/citations/10051409 | http://purl.uniprot.org/core/author | "Lansdorp P."xsd:string |
http://purl.uniprot.org/citations/10051409 | http://purl.uniprot.org/core/author | "Bouffler S."xsd:string |
http://purl.uniprot.org/citations/10051409 | http://purl.uniprot.org/core/author | "van Buul P."xsd:string |
http://purl.uniprot.org/citations/10051409 | http://purl.uniprot.org/core/date | "1999"xsd:gYear |
http://purl.uniprot.org/citations/10051409 | http://purl.uniprot.org/core/name | "Genomics"xsd:string |
http://purl.uniprot.org/citations/10051409 | http://purl.uniprot.org/core/pages | "221-223"xsd:string |
http://purl.uniprot.org/citations/10051409 | http://purl.uniprot.org/core/title | "Elongated telomeres in scid mice."xsd:string |
http://purl.uniprot.org/citations/10051409 | http://purl.uniprot.org/core/volume | "56"xsd:string |
http://purl.uniprot.org/citations/10051409 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/10051409 |
http://purl.uniprot.org/citations/10051409 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/10051409 |
http://purl.uniprot.org/uniprot/#_P97313-mappedCitation-10051409 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/10051409 |
http://purl.uniprot.org/uniprot/P97313 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/10051409 |