| http://purl.uniprot.org/citations/10079183 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10079183 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10079183 | http://www.w3.org/2000/01/rdf-schema#comment | "BCG-CWS is a therapeutically potent immune activator which improves the prognosis of cancer patients. However, the targeting effector cells and molecules for BCG-CWS in the human immune system have not been determined. Here, we found that BCG-CWS activates human monocytes and concomitantly down-regulates expression of a human homologue of chicken MD-1 in the activated monocytes by differential display. According to a previous study, MD-1 forms a complex with the Toll family protein RP-105 on murine B cell lines to facilitate its stable expression. Thus, MD-1 may participate in regulation of innate immune activation on human monocytes. Our results, taken together with these recent findings regarding Toll family proteins, suggest that BCG-CWS acts on monocytes to modulate the human innate immune system via regulation of Toll family proteins."xsd:string |
| http://purl.uniprot.org/citations/10079183 | http://purl.org/dc/terms/identifier | "doi:10.1006/bbrc.1999.0329"xsd:string |
| http://purl.uniprot.org/citations/10079183 | http://purl.org/dc/terms/identifier | "doi:10.1006/bbrc.1999.0329"xsd:string |
| http://purl.uniprot.org/citations/10079183 | http://purl.uniprot.org/core/author | "Matsumoto M."xsd:string |
| http://purl.uniprot.org/citations/10079183 | http://purl.uniprot.org/core/author | "Matsumoto M."xsd:string |
| http://purl.uniprot.org/citations/10079183 | http://purl.uniprot.org/core/author | "Nomura M."xsd:string |
| http://purl.uniprot.org/citations/10079183 | http://purl.uniprot.org/core/author | "Nomura M."xsd:string |
| http://purl.uniprot.org/citations/10079183 | http://purl.uniprot.org/core/author | "Tsuji S."xsd:string |
| http://purl.uniprot.org/citations/10079183 | http://purl.uniprot.org/core/author | "Tsuji S."xsd:string |
| http://purl.uniprot.org/citations/10079183 | http://purl.uniprot.org/core/author | "Hayashi A."xsd:string |
| http://purl.uniprot.org/citations/10079183 | http://purl.uniprot.org/core/author | "Hayashi A."xsd:string |
| http://purl.uniprot.org/citations/10079183 | http://purl.uniprot.org/core/author | "Azuma I."xsd:string |
| http://purl.uniprot.org/citations/10079183 | http://purl.uniprot.org/core/author | "Azuma I."xsd:string |
| http://purl.uniprot.org/citations/10079183 | http://purl.uniprot.org/core/author | "Toyoshima K."xsd:string |
| http://purl.uniprot.org/citations/10079183 | http://purl.uniprot.org/core/author | "Toyoshima K."xsd:string |
| http://purl.uniprot.org/citations/10079183 | http://purl.uniprot.org/core/author | "Seya T."xsd:string |
| http://purl.uniprot.org/citations/10079183 | http://purl.uniprot.org/core/author | "Seya T."xsd:string |
| http://purl.uniprot.org/citations/10079183 | http://purl.uniprot.org/core/author | "Begum N.A."xsd:string |
| http://purl.uniprot.org/citations/10079183 | http://purl.uniprot.org/core/author | "Begum N.A."xsd:string |
| http://purl.uniprot.org/citations/10079183 | http://purl.uniprot.org/core/author | "Shida K."xsd:string |
| http://purl.uniprot.org/citations/10079183 | http://purl.uniprot.org/core/author | "Shida K."xsd:string |
| http://purl.uniprot.org/citations/10079183 | http://purl.uniprot.org/core/date | "1999"xsd:gYear |
| http://purl.uniprot.org/citations/10079183 | http://purl.uniprot.org/core/date | "1999"xsd:gYear |