| http://purl.uniprot.org/citations/10094485 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10094485 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10094485 | http://www.w3.org/2000/01/rdf-schema#comment | "Interleukin-18 binding protein is a novel glycoprotein that we successfully cloned and expressed. First, murine interleukin-18 binding protein was purified from the sera of mice with endotoxin shock using ligand affinity chromatography. The murine interleukin-18 binding protein cDNA was cloned after RT-PCR using mixed primer pair sequences based on partial murine interleukin-18 binding protein amino acid sequence analysis. Subsequently, human interleukin-18 binding protein cDNA was cloned from cDNA libraries of normal human liver using murine interleukin-18 binding protein cDNA as a probe. Next, we transiently expressed recombinant human and murine interleukin-18 binding proteins in COS-1 cells and purified them from culture supernatants. Both recombinant interleukin-18 binding proteins did not exhibit species specificity and prevented interleukin-18 binding to its receptor. In addition, they inhibited interleukine-18 dependent IFN-gamma production from KG-1 cells effectively. These results suggest that the interleukin-18 binding protein may possess interleukine-18 antagonist activity."xsd:string |
| http://purl.uniprot.org/citations/10094485 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0014-5793(99)00148-9"xsd:string |
| http://purl.uniprot.org/citations/10094485 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0014-5793(99)00148-9"xsd:string |
| http://purl.uniprot.org/citations/10094485 | http://purl.uniprot.org/core/author | "Ikeda M."xsd:string |
| http://purl.uniprot.org/citations/10094485 | http://purl.uniprot.org/core/author | "Ikeda M."xsd:string |
| http://purl.uniprot.org/citations/10094485 | http://purl.uniprot.org/core/author | "Mori T."xsd:string |
| http://purl.uniprot.org/citations/10094485 | http://purl.uniprot.org/core/author | "Mori T."xsd:string |
| http://purl.uniprot.org/citations/10094485 | http://purl.uniprot.org/core/author | "Kurimoto M."xsd:string |
| http://purl.uniprot.org/citations/10094485 | http://purl.uniprot.org/core/author | "Kurimoto M."xsd:string |
| http://purl.uniprot.org/citations/10094485 | http://purl.uniprot.org/core/author | "Nishida Y."xsd:string |
| http://purl.uniprot.org/citations/10094485 | http://purl.uniprot.org/core/author | "Nishida Y."xsd:string |
| http://purl.uniprot.org/citations/10094485 | http://purl.uniprot.org/core/author | "Taniai M."xsd:string |
| http://purl.uniprot.org/citations/10094485 | http://purl.uniprot.org/core/author | "Taniai M."xsd:string |
| http://purl.uniprot.org/citations/10094485 | http://purl.uniprot.org/core/author | "Torigoe K."xsd:string |
| http://purl.uniprot.org/citations/10094485 | http://purl.uniprot.org/core/author | "Torigoe K."xsd:string |
| http://purl.uniprot.org/citations/10094485 | http://purl.uniprot.org/core/author | "Ikegami H."xsd:string |
| http://purl.uniprot.org/citations/10094485 | http://purl.uniprot.org/core/author | "Ikegami H."xsd:string |
| http://purl.uniprot.org/citations/10094485 | http://purl.uniprot.org/core/author | "Aizawa Y."xsd:string |
| http://purl.uniprot.org/citations/10094485 | http://purl.uniprot.org/core/author | "Aizawa Y."xsd:string |
| http://purl.uniprot.org/citations/10094485 | http://purl.uniprot.org/core/author | "Tanimoto T."xsd:string |
| http://purl.uniprot.org/citations/10094485 | http://purl.uniprot.org/core/author | "Tanimoto T."xsd:string |
| http://purl.uniprot.org/citations/10094485 | http://purl.uniprot.org/core/author | "Akita K."xsd:string |
| http://purl.uniprot.org/citations/10094485 | http://purl.uniprot.org/core/author | "Akita K."xsd:string |